Výsledky vyhledávání - "Lazar, Iuliana M."

Autor: Tenga, Milagros J., Lazar, Iuliana M.

Publikováno v: BMC Cancer. 14(1)

Background: Cancer cells are characterized by a deregulated cell cycle that facilitates abnormal proliferation by allowing cells to by-pass tightly regulated molecular checkpoints such as the G1/S restriction point. To facilitate early diagnosis and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::57a833f9ce65540013468c87e7a175b7

Zobrazit plný text záznamu

Investigation of in-situ nanoimprinting of cell surface receptors: potential of a novel technique in biomarker research

Autor: Ahmed, Sadia

Biomarkers are biological characteristics that can be observed or measured during disease conditions, and compared to the healthy state. Biomarkers have been used in medical history to study disease progression, to develop drugs, or to predict drug e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2485::d4f863dee792381be6c33612b17c2b17
https://hdl.handle.net/10919/98406

Zobrazit plný text záznamu

Microfluidic Approaches for Probing Protein Phosphorylation in Cells

Autor: Deng, Jingren

Protein phosphorylation plays critical roles in diverse cellular functions, including cell cycle, growth, differentiation, and apoptosis. Deregulated phospho-signaling is often associated with many human diseases and cancers. Despite tremendous effor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2485::7e44b2a49d26b9b3a0f76f96ab83eea6
https://hdl.handle.net/10919/96545

Zobrazit plný text záznamu

Use of Kinase Inhibitors to Illuminate Signaling Pathways in Breast Cancer

Autor: Smith, Nicole R.

In the United States, breast cancer is the most commonly diagnosed cancer and is the second most common cause of cancer-related deaths among women. Among the various subtypes of breast cancer, 25-30% of diagnoses present themselves as human epidermal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2485::77d6a06b92d74a5e2cd9b9478f4800f9
https://hdl.handle.net/10919/92002

Zobrazit plný text záznamu

Exploring Protein-Protein Interactions as Drug Targets for Anti-cancer Therapy with In Silico Workflows

Autor: Alexander Goncearenco, Minghui Li, Benjamin A. Shoemaker, Franco L. Simonetti, Anna R. Panchenko

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Methods in Molecular Biology ISBN: 9781493972005
Proteomics for Drug Discovery: Methods and Protocols

We describe a computational protocol to aid the design of small molecule and peptide drugs that target protein-protein interactions, particularly for anti-cancer therapy. To achieve this goal, we explore multiple strategies, including finding binding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c963740ecfb0e307b5a7c7d79c921a
https://pubmed.ncbi.nlm.nih.gov/28809006

Zobrazit plný text záznamu

Assembly, characterization and evaluation of a 3rd generation nanoparticle based drug carrier for metastatic breast cancer treatment

Autor: Huang, Wei

Cancer is one of the leading causes of death in the world. For women in the U.S. and the European countries, breast cancer is the most common type and it continuously threatens the lives of the patients and causes huge economic losses. Chemotherapy a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2485::7cbeadc7e623230c9884ce1f2ee2b6b1
https://hdl.handle.net/10919/50932

Zobrazit plný text záznamu

Circadian modulation of the estrogen receptor alpha transcription

Autor: Villa, Linda Monique

The circadian clock is a molecular mechanism that synchronizes physiological changes with environmental variations. Disruption of the circadian clock has been linked to increased risk in diseases and a number of disorders (e.g. jet lag, insomnia, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2485::1ed83916a388f996a73bbc81166b9d13
https://hdl.handle.net/10919/77146

Zobrazit plný text záznamu

Proteomic Map of ER+ Breast Cancer Cell Cycle

Autor: Tenga, Milagros Jannet

Cancer is characterized by a deregulation of the cell cycle resulting in abnormal proliferation of cells that can bypass tightly regulated molecular checkpoints. Breast cancer is the most common cancer diagnosed in women, ~70% of cases displaying an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2485::8b8f946a37cbdbf606b4f13a24208221
https://hdl.handle.net/10919/77066

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání