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Human articular cartilage and chondrocytes produce hemopoietic colony-stimulating factors in culture in response to IL-1

Autor: Campbell, I. K., Novak, U., Cebon, J., Layton, J. E., John A Hamilton

Publikováno v: Scopus-Elsevier

The hemopoietic CSF, granulocyte-macrophage CSF (GM-CSF) and granulocyte CSF (G-CSF), are cytokines that mediate the clonal proliferation and differentiation of progenitor cells into mature macrophages and/or granulocytes. We have employed an all-hum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ec452e690325f8890c9c18f23b2dee
https://doi.org/10.4049/jimmunol.147.4.1238

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Ligand-specific utilization of the extracellular membrane-proximal region of the gp130-related signalling receptors

Autor: Hammacher, A, Wijdenes, J, Hilton, D J, Nicola, N A, Simpson, R J, Layton, J E

The receptor gp130 is used by the interleukin-6 (IL-6)-type cytokines, which include IL-6 and leukaemia-inhibitory factor (LIF). To investigate the role of the three extracellular membrane-proximal fibronectin-type-III-like (FNIII) modules of gp130 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3a1bf1b0a35d7cc601cc1a458140be2
https://europepmc.org/articles/PMC1220726/

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Interleukin-4 suppresses granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor levels in stimulated human monocytes

Autor: John A Hamilton, Whitty, G. A., Royston, A. K. M., Cebon, J., Layton, J. E.

Publikováno v: Scopus-Elsevier

Granulocyte colony-stimulating factor (G-CSF) was quantitated in the supernatants of lipopolysaccharide (LPS)-treated human monocytes by ELISA. Unlike previous reports, the lymphokines, interleukin-4 (IL-4) and interferon-gamma (IFN-gamma), were unab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9052d68be634689bc8b771afd6030496
https://europepmc.org/articles/PMC1421558/

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