Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Laylan Hamid"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 2, Pp 496-510 (2022)
Genetic variation in apolipoprotein E (APOE) influences Alzheimer's disease (AD) risk. APOE ε4 alleles are the strongest genetic risk factor for late onset sporadic AD. The AD risk is dose dependent, as those carrying one APOE ε4 allele have a 2–
Externí odkaz:
https://doaj.org/article/c613d0afe542406d814cd27e0b00d475
Autor:
Benjamin R. Troutwine, Taylor A. Strope, Edziu Franczak, Colton R. Lysaker, Laylan Hamid, Clayton Mansel, Julia A. Stopperan, Cynthia M. Gouvion, Mohammad Haeri, Russell H. Swerdlow, Heather M. Wilkins
Publikováno v:
Neurobiology of Disease, Vol 171, Iss , Pp 105781- (2022)
Introduction: Mitochondrial dysfunction is observed in Alzheimer's disease (AD). However, the relationship between functional mitochondrial deficits and AD pathologies is not well established in human subjects. Methods: Post-mortem human brain tissue
Externí odkaz:
https://doaj.org/article/582d0d131aae48a1957bd062e00a2945
Publikováno v:
Acta pharmaceutica Sinica. B. 12(2)
Genetic variation in apolipoprotein E (APOE) influences Alzheimer's disease (AD) risk. APOE e4 alleles are the strongest genetic risk factor for late onset sporadic AD. The AD risk is dose dependent, as those carrying one APOE e4 allele have a 2–3-