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of 6
pro vyhledávání: '"Layla Kawarada"'
Autor:
Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006355 (2016)
Reversible infantile liver failure (RILF) is a unique heritable liver disease characterized by acute liver failure followed by spontaneous recovery at an early stage of life. Genetic mutations in MTU1 have been identified in RILF patients. MTU1 is a
Externí odkaz:
https://doaj.org/article/93f732f5c91e411a9053a7be405206e9
Publikováno v:
FEBS lettersReferences. 595(12)
AlkB homolog 1 (ALKBH1) is responsible for the biogenesis of 5-formylcytidine (f5 C) on mitochondrial tRNAMet and essential for mitochondrial protein synthesis. The brain, especially the hippocampus, is highly susceptible to mitochondrial dysfunction
Publikováno v:
Nucleic Acids Research
ALKBH1 is a 2-oxoglutarate- and Fe2+-dependent dioxygenase responsible for multiple cellular functions. Here, we show that ALKBH1 is involved in biogenesis of 5-hydroxymethyl-2΄-O-methylcytidine (hm5Cm) and 5-formyl-2΄-O-methylcytidine (f5Cm) at th
Autor:
Yoshihiro Komohara, Atsushi Fujimura, Yuichi Oike, Takeo Suzuki, Kazuhito Tomizawa, Tsutomu Suzuki, Layla Kawarada, Fan Yan Wei, Motohiro Takeya, Taku Kaitsuka, Yong Wu, Kimi Araki
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006355 (2016)
PLoS Genetics
PLoS Genetics
Reversible infantile liver failure (RILF) is a unique heritable liver disease characterized by acute liver failure followed by spontaneous recovery at an early stage of life. Genetic mutations in MTU1 have been identified in RILF patients. MTU1 is a
Publikováno v:
Nature chemical biology. 12(7)
In human mitochondria, the AUA codon encodes methionine via a mitochondrial transfer RNA for methionine (mt-tRNA(Met)) that contains 5-formylcytidine (f(5)C) at the first position of the anticodon (position 34). f(5)C34 is required for deciphering th
Publikováno v:
Nucleic Acids Research; 7/7/2017, Vol. 45 Issue 12, p7401-7415, 15p