Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Layal El Hajjar"'
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 24, Iss 12, p 354 (2023)
Background: Cardiovascular disease that is caused by atherosclerosis is the leading cause of death worldwide. Atherosclerosis is primarily triggered by endothelial dysfunction and the accumulation of modified low-density lipoprotein (LDL) particles i
Externí odkaz:
https://doaj.org/article/1618bf548046496ea6446307c90b62e2
Autor:
Ghada Chamandi, Layal El-Hajjar, Abdallah El Kurdi, Morgane Le Bras, Rihab Nasr, Jacqueline Lehmann-Che
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2300 (2023)
Breast cancer (BC), the most prevalent cancer in women, is a heterogenous disease. Despite advancements in BC diagnosis, prognosis, and therapeutics, survival rates have drastically decreased in the metastatic setting. Therefore, BC still remains a m
Externí odkaz:
https://doaj.org/article/428a574f79ec45d986156d60b706487b
Autor:
Layal EL-Hajjar, Abdullah Shaito, Nour Jalaleddine, Kazem Zibara, Jalal M. Kazan, Jamal El-Saghir, Marwan El-Sabban
Publikováno v:
Data in Brief, Vol 22, Iss , Pp 635-638 (2019)
Bevacizumab or Avastin® (Av), the recombinant antibody targeting VEGF, improves progression-free but not overall survival of metastatic breast cancer patients due to development of Av resistance. We showed that Av-therapy-induced inflammatory microe
Externí odkaz:
https://doaj.org/article/33e7114a9460458e83134242ea4591c2
Autor:
Mohammad El-Harakeh, Jessica Saliba, Kawthar Sharaf Aldeen, May Haidar, Layal El Hajjar, Mireille Kallassy Awad, Jana G Hashash, Margret Shirinian, Marwan El-Sabban
Publikováno v:
World Journal of Gastroenterology. 28:5845-5864
Inflammatory bowel disease (IBD) constitutes a substantial risk factor for colorectal cancer. Connexin 43 (Cx43) is a protein that forms gap junction (GJ) complexes involved in intercellular communication, and its expression is altered under patholog
Publikováno v:
Current Protocols. 3
Autor:
Layal El-Hajjar, Jessica Saliba, Mario Karam, Abdullah Shaito, Hiba El Hajj, Marwan El-Sabban
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2958
Volume 24
Issue 3
Pages: 2958
Gap-junction-forming connexins are exquisitely regulated by post-translational modifications (PTMs). In particular, the PTM of connexin 43 (Cx43), a tumor suppressor protein, regulates its turnover and activity. Here, we investigated the interaction
Autor:
Leila Jaafar, Isabelle Fakhoury, Wassim Abou-Kheir, Mirvat El-Sibai, Layal El-Hajjar, Sahar Saab
Publikováno v:
Human Cell. 34:607-623
Prostate cancer is the second most commonly diagnosed cancer in men and one of the main leading causes of cancer deaths among men worldwide. Rapid uncontrolled growth and the ability to metastasize to other sites are key hallmarks in cancer developme
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2837
Cardiovascular disease as a result of atherosclerosis is a leading cause of death worldwide. Atherosclerosis is primarily caused by the dysfunction of vascular endothelial cells and the subendothelial accumulation of oxidized forms of low-density lip
Autor:
Layal El-Hajjar, Kazem Zibara, Jamal El-Saghir, Jalal M. Kazan, Marwan El-Sabban, Abdullah Shaito, Nour Jalaleddine
Publikováno v:
Cellular Signalling. 53:400-412
Background Bevacizumab or Avastin® (Av) is an anti-vascular endothelial growth factor agent. It does not improve survival of breast cancer patients due to development of refractoriness. Av treatment was shown to increase inflammation in a diabetic m