Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Lay Teng, Ang"'
Autor:
Ivet A. Yordanova, Angelika Lander, Annette Wahlbrink, Jonathan S. Towner, César G. Albariño, Lay Teng Ang, Joseph B. Prescott
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-11 (2024)
Abstract Marburg virus (MARV) is a highly pathogenic filovirus and a causative agent of sporadic zoonotic viral hemorrhagic fever outbreaks with high case fatality rates. In humans, filoviruses like MARV and Zaire Ebola virus (EBOV) target, among oth
Externí odkaz:
https://doaj.org/article/fdcbc1dc0bdd43508a53587205bc6850
Autor:
Sivakamasundari Vijayakumar, Roberta Sala, Gugene Kang, Angela Chen, Michelle Ann Pablo, Abidemi Ismail Adebayo, Andrea Cipriano, Jonas L. Fowler, Danielle L. Gomes, Lay Teng Ang, Kyle M. Loh, Vittorio Sebastiano
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Generating primordial germ cell-like cells (PGCLCs) from human pluripotent stem cells (hPSCs) advances studies of human reproduction and development of infertility treatments, but often entails complex 3D aggregates. Here we develop a simpli
Externí odkaz:
https://doaj.org/article/8e8d0192fda64084872f8d3b27e40339
Autor:
Kai-Qian Kam, Koh Cheng Thoon, Wen Sim Nancy Tee, Michelle Lay Teng Ang, Natalie Woon Hui Tan, Kee Thai Yeo, Jiahui Li, Chia Yin Chong
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background The current group B streptococcal (GBS) preventive measures had reduced invasive GBS early onset disease (EOD) incidences worldwide, but the late onset disease (LOD) incidences had remained unchanged. Administration of a safe and
Externí odkaz:
https://doaj.org/article/d211c89c14dd4f03bb006a000f24f878
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 273-290 (2021)
Epithelial cells in the liver (known as hepatocytes) are high-performance engines of myriad metabolic functions and versatile responders to liver injury. As hepatocytes metabolize amino acids, alcohol, drugs, and other substrates, they produce and ar
Externí odkaz:
https://doaj.org/article/8cbd639ed031408ca7c8ee10358e1593
Autor:
Lay Teng Ang, Antson Kiat Yee Tan, Matias I. Autio, Su Hua Goh, Siew Hua Choo, Kian Leong Lee, Jianmin Tan, Bangfen Pan, Jane Jia Hui Lee, Jen Jen Lum, Christina Ying Yan Lim, Isabelle Kai Xin Yeo, Chloe Jin Yee Wong, Min Liu, Jueween Ling Li Oh, Cheryl Pei Lynn Chia, Chet Hong Loh, Angela Chen, Qingfeng Chen, Irving L. Weissman, Kyle M. Loh, Bing Lim
Publikováno v:
Cell Reports, Vol 22, Iss 8, Pp 2190-2205 (2018)
Summary: How are closely related lineages, including liver, pancreas, and intestines, diversified from a common endodermal origin? Here, we apply principles learned from developmental biology to rapidly reconstitute liver progenitors from human pluri
Externí odkaz:
https://doaj.org/article/18dfda95bb854672b8638aaa6e3a3810
Autor:
Alana Nguyen, Karen M. Gonzalez, Yue Zhang, Kristy Red-Horse, Brian C. Raftrey, Robert Roth, Andrew H. Chang, Mingming Zhao, Xiaochen Fan, Ian M. Williams, Lay Teng Ang, Pamela E. Rios Coronado, Kyle M. Loh, Ragini Phansalkar, Timothy Chai, Gaetano D'Amato, Emily Trimm, Daniel Bernstein, Raquel Racelis
Publikováno v:
Circulation research. 129(7)
Rationale: Coronary artery disease is the leading cause of death worldwide, but there are currently no methods to stimulate artery growth or regeneration in diseased hearts. Studying how arteries are built during development could illuminate strategi
Autor:
Lay Teng Ang, Alana T. Nguyen, Kevin J. Liu, Angela Chen, Xiaochen Xiong, Matthew Curtis, Renata M. Martin, Brian C. Raftry, Chun Yi Ng, Uwe Vogel, Angelika Lander, Benjamin J. Lesch, Jonas L. Fowler, Alyssa R. Holman, Timothy Chai, Siva Vijayakumar, Fabian P. Suchy, Toshinobu Nishimura, Joydeep Bhadury, Matthew H. Porteus, Hiromitsu Nakauchi, Christine Cheung, Steven C. George, Kristy Red-Horse, Joseph B. Prescott, Kyle M. Loh
Publikováno v:
Cell
Stem cell research endeavors to generate specific subtypes of classically defined "cell types." Here, we generate90% pure human artery or vein endothelial cells from pluripotent stem cells within 3-4 days. We specified artery cells by inhibiting vein
Autor:
Jonas L Fowler, Angela Chen, Sivakamasundari Vijayakumar, Abidemi Adebayo, Roberta Sala, Lay Teng Ang, Vittorio Sebastiano, Kyle M. Loh, Andrea Cipriano, Gugene Kang
Generating primordial germ cells (PGCs) from human pluripotent stem cells (hPSCs) advances studies of human reproduction and development of infertility treatments, but currently entails complex 3D aggregates. Here we develop a simplified, monolayer m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc2fc1299d7ccfe23ee3f748357bf60f
https://doi.org/10.21203/rs.3.rs-113078/v1
https://doi.org/10.21203/rs.3.rs-113078/v1
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 273-290 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 273-290 (2021)
Epithelial cells in the liver (known as hepatocytes) are high-performance engines of myriad metabolic functions and versatile responders to liver injury. As hepatocytes metabolize amino acids, alcohol, drugs, and other substrates, they produce and ar
Publikováno v:
Wiley Interdiscip Rev Dev Biol
Too many choices can be problematic. This is certainly the case for human pluripotent stem cells (hPSCs): they harbor the potential to differentiate into hundreds of cell types; yet it is highly challenging to exclusively differentiate hPSCs into a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b07a85ecaf8a686cfa7a7324ea3a78c
https://europepmc.org/articles/PMC7397816/
https://europepmc.org/articles/PMC7397816/