Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Lay Khoon Too"'
Autor:
Lay Khoon Too, Weiyong Shen, Dario A. Protti, Atomu Sawatari, Dylan A. Black, Catherine A. Leamey, Jin Y. Huang, So-Ra Lee, Ashish E. Mathai, Leszek Lisowski, John Y. Lin, Mark C. Gillies, Matthew P. Simunovic
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract The common final pathway to blindness in many forms of retinal degeneration is the death of the light-sensitive primary retinal neurons. However, the normally light-insensitive second- and third-order neurons persist optogenetic gene therapy
Externí odkaz:
https://doaj.org/article/e6ac0f842ad64bb388befe61565632fa
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/241123a881e4438dae9e6274be71b3dd
Autor:
Lay Khoon Too, Matthew P. Simunovic
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Over the past two decades, progress in our understanding of glial function has been revolutionary. Within the retina, a subset of glial cells termed the “Müller glia (MG),” have been demonstrated to play key roles in retinal homeostasis, structu
Externí odkaz:
https://doaj.org/article/ad82ade212f042aab1dcaec1e8fdb528
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Age-related neurodegenerative diseases, such as Alzheimer disease (AD) and age-related macular degeneration (AMD), are multifactorial and have diverse genetic and environmental risk factors. Despite the complex nature of the diseases, there is long-s
Externí odkaz:
https://doaj.org/article/2b9e03dc20b74eeaaa906b02f18e4733
Autor:
Roger Pamphlett, Svetlana Cherepanoff, Lay Khoon Too, Stephen Kum Jew, Philip A Doble, David P Bishop
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0241054 (2020)
ObjectiveToxic metals are suspected to play a role in the pathogenesis of age-related macular degeneration. However, difficulties in detecting the presence of multiple toxic metals within the intact human retina, and in separating primary metal toxic
Externí odkaz:
https://doaj.org/article/3c6d0da30c6e487fae45465cfcd1e3cd
Autor:
Lay Khoon Too, Andrew Mitchell
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 1, Pp 125-126 (2021)
Externí odkaz:
https://doaj.org/article/3df0afeb6ecb4eb8a43ff50f44b6a3ea
Autor:
Lay Khoon Too, Kong M. Li, Cacang Suarna, Ghassan J. Maghzal, Roland Stocker, Iain S. McGregor, Nicholas H. Hunt
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 275-287 (2016)
This article demonstrates behavioral changes in mice in response to free adaptation and drinking session adaptation modules implemented in their social home environment, the IntelliCage. These data complement the study “Deletion of TDO2, IDO-1 and
Externí odkaz:
https://doaj.org/article/f350cec6827a4a8ba5b378fdeaac196c
Publikováno v:
Retina. 43:158-161
Purpose There is renewed interest in subretinal drug delivery as the result of novel and emerging treatments for retinal diseases, including retinal gene therapy. However, our knowledge of the distribution of subretinally delivered drugs is incomplet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbb57825e2b8a8c3d991338a0dd1e9c
https://doi.org/10.1097/iae.0000000000002800
https://doi.org/10.1097/iae.0000000000002800
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f88a4247b1dee27e48698073fadb0d
https://pubmed.ncbi.nlm.nih.gov/35185475
https://pubmed.ncbi.nlm.nih.gov/35185475
Autor:
Fred K. Chen, Lawrence A. Yannuzzi, K. Bailey Freund, Christine A. Curcio, Sarah Mrejen, Rosa Dolz-Marco, Orly Gal-Or, Murray C. Killingsworth, Svetlana Cherepanoff, Lay Khoon Too, Chandrakumar Balaratnasingam, Randev Mendis
Publikováno v:
Ophthalmology. 125:100-118
Purpose To define the range and life cycles of cuticular drusen phenotypes using multimodal imaging and to review the histologic characteristics of cuticular drusen. Design Retrospective, observational cohort study and experimental laboratory study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b362da2f9b3a1968c77850f024fc836c
https://doi.org/10.1016/j.ophtha.2017.08.033
https://doi.org/10.1016/j.ophtha.2017.08.033