Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Laxminarayanan, Krishnan"'
Autor:
Hannah A. Strobel, Steven A. LaBelle, Laxminarayanan Krishnan, Jacob Dale, Adam Rauff, A. Marsh Poulson, Nathan Bader, Jason E. Beare, Klevis Aliaj, Jeffrey A. Weiss, James B. Hoying
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Vascular connectivity between adjacent vessel beds within and between tissue compartments is essential to any successful neovascularization process. To establish new connections, growing neovessels must locate other vascular elements during angiogene
Externí odkaz:
https://doaj.org/article/8a72ba4d88b4439a9ce3072157f7c678
Autor:
Lauren B. Priddy, Laxminarayanan Krishnan, Marian H. Hettiaratchi, Sukhita Karthikeyakannan, Nikhil Gupte, Robert E. Guldberg
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 41(1)
Treatment of large bone defects with supraphysiological doses of bone morphogenetic protein-2 (BMP-2) has been associated with complications including heterotopic ossification (HO), inflammation, and pain, presumably due to poor spatiotemporal contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ac81e462a53e22bdcba8c5ee4fd382
https://pubmed.ncbi.nlm.nih.gov/35340049
https://pubmed.ncbi.nlm.nih.gov/35340049
Autor:
Laxminarayanan Krishnan, Robert E. Guldberg, Amelia Yin, Anita E. Qualls, Nathan T. Jenkins, William M. Southern, Anna S. Nichenko, Jarrod A. Call, Melissa J. McGranahan, Sarah M. Greising, Hang Yin, Luke J. Mortensen, Kayvan Forouhesh Tehrani
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
Volumetric muscle loss (VML) injury is characterized by a non-recoverable loss of muscle fibers due to ablative surgery or severe orthopaedic trauma, that results in chronic functional impairments of the soft tissue. Currently, the effects of VML on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9d3fd8fc9c1f8ccbac8c5052a85eec
http://link.springer.com/article/10.1038/s41598-019-40606-6
http://link.springer.com/article/10.1038/s41598-019-40606-6
Autor:
Levi B. Wood, Krishnendu Roy, Laxminarayanan Krishnan, Theresa Kotanchek, Robert E. Guldberg, Albert Cheng, Casey E. Vantucci, Marissa A. Ruehle
Publikováno v:
Proc Natl Acad Sci U S A
Severe traumatic injuries are a widespread and challenging clinical problem, and yet the factors that drive successful healing and restoration of function are still not well understood. One recently identified risk factor for poor healing outcomes is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa63301935a5e519c0ae0355fd9bba4
https://doi.org/10.1073/pnas.2017889118
https://doi.org/10.1073/pnas.2017889118
Autor:
Marissa A. Ruehle, Jeffrey A. Weiss, James B. Hoying, Robert E. Guldberg, Steven A. LaBelle, Laxminarayanan Krishnan
Publikováno v:
Vascularization for Tissue Engineering and Regenerative Medicine ISBN: 9783319210568
Vascularization for Tissue Engineering and Regenerative Medicine
Vascularization for Tissue Engineering and Regenerative Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3300e491f012a038a01495d6e0d87ee
https://doi.org/10.1007/978-3-319-54586-8_19
https://doi.org/10.1007/978-3-319-54586-8_19
Autor:
Joel D. Boerckel, Laxminarayanan Krishnan, Nick J. Willett, Jeffrey A. Weiss, Marissa A. Ruehle, Levi B. Wood, Robert E. Guldberg, Steven A. LaBelle, E. A. Eastburn
Publikováno v:
Science Advances
Extracellular matrix deformation temporally regulates angiogenesis and upstream angiogenic and mechanosensitive pathways.
Mechanical cues influence tissue regeneration, and although vasculature is known to be mechanically sensitive, little is kn
Mechanical cues influence tissue regeneration, and although vasculature is known to be mechanically sensitive, little is kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09adcf8b746e3b8f4868f9978e0cdd3
http://europepmc.org/articles/PMC7442478
http://europepmc.org/articles/PMC7442478
Akademický článek
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Autor:
Robert E. Guldberg, Krishnendu Roy, Levi B. Wood, Laxminarayanan Krishnan, Laura D. Weinstock, Albert Cheng, Pallab Pradhan
Publikováno v:
J Orthop Res
Delayed union and nonunion are a significant concern in long bone fractures and spinal fusions. Treatment of nonunion often entails multiple revision surgeries that further increase the financial, physical, and emotional burden on patients. The optim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34545cbba4fd78ca8a2b87cfe520a062
https://doi.org/10.1002/jor.24186
https://doi.org/10.1002/jor.24186
Autor:
Robert E. Guldberg, Lisa Tran, Hazel Y. Stevens, Camden Esancy, Laxminarayanan Krishnan, Brett S. Klosterhoff, Lauren B. Priddy
Publikováno v:
Acta Biomaterialia. 49:101-112
Bone morphogenetic protein-2 (BMP-2), delivered on absorbable collagen sponge, is frequently used to treat bone defects. However, supraphysiological BMP-2 doses are common and often associated with complications such as heterotopic ossification and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28cf14f50919fb928b86e74ba3f6c690
https://doi.org/10.1016/j.actbio.2016.12.012
https://doi.org/10.1016/j.actbio.2016.12.012
Autor:
Jeffrey A. Weiss, Laxminarayanan Krishnan, Levi B. Wood, Nick J. Willett, Marissa A. Ruehle, Robert E. Guldberg, Joel D. Boerckel, Emily A. Eastburn, Steven A. LaBelle
Neovascularization is a critical early step toward successful tissue regeneration during wound healing. While vasculature has long been recognized as highly mechanosensitive (to fluid shear, pulsatile luminal pressure, etc.), the effects of extracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5d9d799ff77b2d61b0a646cfb6db2d
https://doi.org/10.1101/2020.01.14.906354
https://doi.org/10.1101/2020.01.14.906354