Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laxmikant G. Gadhe"'
Autor:
Rakesh Kumar, Murali Sastry, Pradeep Kadu, Samir K. Maji, Suditi Neekhra, Satyaprakash Pandey, Laxmikant G. Gadhe, Rohit Srivastava
Publikováno v:
The Journal of Physical Chemistry Letters. 11:10489-10496
Photothermal effects of metal nanoparticles (NPs) are used for various biotechnological applications. Although NPs have been used in a polymerase chain reaction (PCR), the effects of shape on the photothermal properties and its efficiency on PCR are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea3c7461df600fa65f36a63d811af0d
https://doi.org/10.1021/acs.jpclett.0c02708
https://doi.org/10.1021/acs.jpclett.0c02708
Autor:
Rakesh Kumar, Namrata Singh, Per Nilsson, Samir K. Maji, Ambuja Navalkar, Pardeep Kumar, Ganesh M. Mohite, Ashutosh Kumar, Maheswaran Shanmugam, Makoto Shimozawa, Rajlaxmi Panigrahi, Shalini Tripathi, Shaffi Manchanda, Jan Johansson, Laxmikant G. Gadhe, Narayanaperumal Pravin
Publikováno v:
Journal of Neurochemistry. 156:1003-1019
Protein aggregation into amyloid fibrils is a key feature of a multitude of neurodegenerative diseases such as Alzheimer's, Parkinson's, and Prion disease. To detect amyloid fibrils, fluorophores with high sensitivity and better efficiency coupled wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8387100a929fd69d90fe3b7917d7523
https://doi.org/10.1111/jnc.15138
https://doi.org/10.1111/jnc.15138
Publikováno v:
Analytical Chemistry. 92:10336-10341
The misfolding and aggregation of proteins leading to amyloid formation has been linked to numerous diseases, necessitating the development of tools to monitor the fibrillation process. Here, we report an intramolecular charge transfer (ICT) dye, DMN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366005ca6743430133624eaabaff014e
https://doi.org/10.1021/acs.analchem.0c00379
https://doi.org/10.1021/acs.analchem.0c00379
Autor:
Sandhya Bhatia, Amrendra K. Singh, Jaladhar Mahato, Soumik Ray, Ranjith Padinhateeri, Samir K. Maji, Laxmikant G. Gadhe, Siddhartha Maiti, Ambuja Navalkar, Roland Riek, Debdeep Chatterjee, Rajlaxmi Panigrahi, G. Krishnamoorthy, Nitu Singh, Sushil Kumar Pandey, Rakesh Kumar, Arindrajit Chowdhury, Komal Patel, Surabhi Mehra, Juan Gerez, Debalina Datta, Ashutosh Kumar
Publikováno v:
Nature Chemistry. 12:705-716
α-Synuclein (α-Syn) aggregation and amyloid formation is directly linked with Parkinson's disease pathogenesis. However, the early events involved in this process remain unclear. Here, using the in vitro reconstitution and cellular model, we show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99e38a0de7a31a39f7e078238d31ac9d
https://doi.org/10.1038/s41557-020-0465-9
https://doi.org/10.1038/s41557-020-0465-9
Publikováno v:
Biomolecules
Biomolecules, Vol 11, Iss 1419, p 1419 (2021)
Biomolecules, Vol 11, Iss 1419, p 1419 (2021)
Abnormal accumulation of aggregated α-synuclein (α-Syn) is seen in a variety of neurodegenerative diseases, including Parkinson’s disease (PD), multiple system atrophy (MSA), dementia with Lewy body (DLB), Parkinson’s disease dementia (PDD), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0144e6f8784059172356300a2261854f
http://europepmc.org/articles/PMC8533119
http://europepmc.org/articles/PMC8533119
Autor:
Debalina Datta, Namrata Singh, Laxmikant G. Gadhe, Samir K. Maji, Ambuja Navalkar, A. Paul, Pradeep Kadu, Santosh Kumar, Reeba S. Jacob, Shantibhushan Senapati, Chinmai Pindi, Shinjinee Sengupta, Soumik Ray, Debdeep Chatterjee, Praful S. Singru
Synergistic-aggregation and cross-seeding by two different amyloid proteins/peptides are well evident in various neurological disorders. However, this phenomenon is not well studied in functional amyloid aggregation. Here, we show Prolactin (PRL) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f9d8c4671e24ce90515514c99c47ebb
https://doi.org/10.1101/2021.08.31.458467
https://doi.org/10.1101/2021.08.31.458467
Autor:
Surabhi Mehra, Aishwarya Ramakrishnan, Rakesh Kumar, Ganesh M. Mohite, Vikas Chandrawanshi, Dhiman Ghosh, Samir K. Maji, Ambuja Navalkar, Laxmikant G. Gadhe, Basil Alias, Subhadeep Das, Sarika Mehra
Publikováno v:
Biochemistry. 57:5014-5028
Amyloid formation of α-synuclein (α-Syn) and its familial mutations are directly linked with Parkinson's disease (PD) pathogenesis. Recently, a new familial α-Syn mutation (A53E) was discovered, associated with an early onset aggressive form of PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639e848cd70c033440195b280fbce962
https://doi.org/10.1021/acs.biochem.8b00321
https://doi.org/10.1021/acs.biochem.8b00321
Autor:
Jaladhar Mahato, Rakesh Kumar, Soumik Ray, Sushil Kumar Pandey, Siddhartha Maiti, Ranjith Padinhateeri, Amrendra K. Singh, Samir K. Maji, G. Krishnamoorthy, Juan Gerez, Debalina Datta, Ambuja Navalkar, Laxmikant G. Gadhe, Rajlaxmi Panigrahi, Surabhi Mehra, Ashutosh Kumar, Debdeep Chatterjee, Komal Patel, Nitu Singh, Sandhya Bhatia, Roland Riek, Arindrajit Chowdhury
SUMMARYα-Synuclein (α-Syn) aggregation and amyloid formation is directly linked with Parkinson’s disease (PD) pathogenesis. However, the early events involved in this process remain unclear. Here, using in vitro reconstitution and cellular model,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc13e24524b2e0424e74a620fd3467a
https://doi.org/10.1101/619858
https://doi.org/10.1101/619858
Autor:
Laxmikant G. Gadhe, Dhiman Ghosh, Ashutosh Kumar, Debdeep Chatterjee, A. Anoop, Nitu Singh, Narendra Nath Jha, Mrityunjoy Mondal, Rakesh Kumar, Reeba S. Jacob, Soumik Ray, Surabhi Mehra, Samir K. Maji, Subhadeep Das
Parkinson's disease is mainly a sporadic disorder in which both environmental and cellular factors play a major role in the initiation of this disease. Glycosaminoglycans (GAG) are integral components of the extracellular matrix and are known to infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e68205d2a4feaadc6ba7627492cd94
https://europepmc.org/articles/PMC6109935/
https://europepmc.org/articles/PMC6109935/
Autor:
Subhadeep Das, Debdeep Chatterjee, Samir K. Maji, Namrata Singh, Ambuja Navalkar, Rajlaxmi Panigrahi, Nitu Singh, Rakesh Kumar, Soumik Ray, Debalina Datta, Surabhi Mehra, Ashutosh Kumar, Laxmikant G. Gadhe, Ganesh M. Mohite
Publikováno v:
Biochemistry. 57(35)
The involvement of α-synuclein (α-Syn) amyloid formation in Parkinson's disease (PD) pathogenesis is supported by the discovery of α-Syn gene (SNCA) mutations linked with familial PD, which are known to modulate the oligomerization and aggregation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410f6b60456e51561790e75d7162cbdd
https://pubmed.ncbi.nlm.nih.gov/29771508
https://pubmed.ncbi.nlm.nih.gov/29771508