Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Laxmi Sunuwar"'
Autor:
Jennifer Foulke-Abel, Huimin Yu, Laxmi Sunuwar, Ruxian Lin, James M. Fleckenstein, James B. Kaper, Mark Donowitz
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
Diarrhea caused by enterotoxigenic Escherichia coli (ETEC) has a continuing impact on residents and travelers in underdeveloped countries. Both heat-labile (LT) and heat-stable (ST) enterotoxins contribute to pathophysiology via induction of cyclic n
Externí odkaz:
https://doaj.org/article/16f91fadd30948fb9fd01350ba13a021
Autor:
Laxmi Sunuwar, Azra Frkatović, Sodbo Sharapov, Qinchuan Wang, Heather M. Neu, Xinqun Wu, Talin Haritunians, Fengyi Wan, Sarah Michel, Shaoguang Wu, Mark Donowitz, Dermot McGovern, Gordan Lauc, Cynthia Sears, Joanna Melia
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
ZIP8 is a metal transporter with a role in manganese (Mn) homeostasis. A common genetic variant in ZIP8 (rs13107325; A391T) ranks in the top 10 of pleiotropic SNPs identified in GWAS; A391T has associations with an increased risk of schizophrenia, ob
Externí odkaz:
https://doaj.org/article/c8a8d7250ef44726afdebb8c100fb512
Autor:
Magdalena Kasendra, Raymond Luc, Jianyi Yin, Dimitris V Manatakis, Gauri Kulkarni, Carolina Lucchesi, Josiah Sliz, Athanasia Apostolou, Laxmi Sunuwar, Jenifer Obrigewitch, Kyung-Jin Jang, Geraldine A Hamilton, Mark Donowitz, Katia Karalis
Publikováno v:
eLife, Vol 9 (2020)
Induction of intestinal drug metabolizing enzymes can complicate the development of new drugs, owing to the potential to cause drug-drug interactions (DDIs) leading to changes in pharmacokinetics, safety and efficacy. The development of a human-relev
Externí odkaz:
https://doaj.org/article/d50dcbcf666140a997178741be620615
Publikováno v:
bioRxiv
Manganese is a diet−derived micronutrient that is essential for critical cellular processes like redox homeostasis, protein glycosylation, and lipid and carbohydrate metabolism. Control of Mn availability, especially at the local site of infection,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9a504e07851d4340658f5bf1ed5d28
https://europepmc.org/articles/PMC10055399/
https://europepmc.org/articles/PMC10055399/
Autor:
Katia Karalis, Chung-Ming Tse, Jianyi Yin, Magdalena Kasendra, C. Conover Talbot, Laxmi Sunuwar, Huimin Yu, Robert N. Cole, Mark Donowitz, Tatiana Boronina
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
There is increasing evidence that the study of normal human enteroids duplicates many known aspects of human intestinal physiology. However, this epithelial cell-only model lacks the many nonepithelial intestinal cells present in the gastrointestinal
Autor:
Laxmi Sunuwar, Joanna P. Melia
Publikováno v:
Gastroenterology. 162:S-958
Autor:
Fengyi Wan, Sarah L. J. Michel, Shaoguang Wu, Joanna M.P. Melia, Talin Haritunians, Xinqun Wu, Cynthia L. Sears, Sodbo Zh Sharapov, Laxmi Sunuwar, Heather M. Neu, Azra Frkatović, Mark Donowitz, Gordan Lauc, Qinchuan Wang, Dermot P.B. McGovern
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
JCI Insight
JCI Insight
ZIP8 is a metal transporter with a role in manganese (Mn) homeostasis. A common genetic variant in ZIP8 (rs13107325; A391T) ranks in the top 10 of pleiotropic SNPs identified in GWAS; A391T has associations with an increased risk of schizophrenia, ob
Autor:
Laxmi Sunuwar, James M. Fleckenstein, Mark Donowitz, James B. Kaper, Katia Karalis, Magdalena Kasendra, Jianyi Yin
Publikováno v:
Infect Immun
Modeling host-pathogen interactions with human intestinal epithelia using enteroid monolayers on permeable supports (such as Transwells) represents an alternative to animal studies or use of colon cancer-derived cell lines. However, the static monola
Autor:
Athanasia Apostolou, Geraldine A. Hamilton, Laxmi Sunuwar, Carolina Lucchesi, Katia Karalis, Josiah Sliz, Dimitris V. Manatakis, Mark Donowitz, Jenifer Obrigewitch, Gauri Kulkarni, Raymond Luc, Kyung-Jin Jang, Jianyi Yin, Magdalena Kasendra
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Induction of intestinal drug metabolizing enzymes can complicate the development of new drugs, owing to the potential to cause drug-drug interactions (DDIs) leading to changes in pharmacokinetics, safety and efficacy. The development of a human-relev
Autor:
Geraldine A. Hamilton, Laxmi Sunuwar, Carolina Lucchesi, Katia Karalis, Raymond Luc, Mark Donowitz, Josiah Sliz, Magdalena Kasendra, Jenifer Obrigewitch, Dimitris V. Manatakis, Jianyi Yin, Kyung-Jin Jang, Gauri Kulkarni, Athanasia Apostolou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::607cc0d10cb3c7eb05ba0ff324ea495d
https://doi.org/10.7554/elife.50135.sa2
https://doi.org/10.7554/elife.50135.sa2