Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Laxmi Silwal-Pandit"'
Autor:
Thomas Fleischer, Mads Haugland Haugen, Jørgen Ankill, Laxmi Silwal‐Pandit, Anne‐Lise Børresen‐Dale, Ingrid Hedenfalk, Thomas Hatschek, Jörg Tost, Olav Engebraaten, Vessela N. Kristensen
Publikováno v:
Molecular Oncology, Vol 18, Iss 8, Pp 2042-2059 (2024)
Treatment with the anti‐angiogenic drug bevacizumab in addition to chemotherapy has shown efficacy for breast cancer in some clinical trials, but better biomarkers are needed to optimally select patients for treatment. Here, we present an omics app
Externí odkaz:
https://doaj.org/article/943a77752b1e4da48443c28cd3393e9f
Autor:
Stina Margrethe Stålberg, Laxmi Silwal-Pandit, Nasser Ezzatkhah Bastani, Daniel Johan Hammer Nebdal, Ole Christian Lingjærde, Bjørn Steen Skålhegg, Elin Hegland Kure
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Periampullary cancers, including pancreatic ductal adenocarcinoma, ampullary-, cholangio-, and duodenal carcinoma, are frequently diagnosed in an advanced stage and are associated with poor overall survival. They are difficult to differentia
Externí odkaz:
https://doaj.org/article/4cdb6aa097204ee583950af228302561
Autor:
Kristi Krüger, Laxmi Silwal-Pandit, Elisabeth Wik, Oddbjørn Straume, Ingunn M. Stefansson, Elin Borgen, Øystein Garred, Bjørn Naume, Olav Engebraaten, Lars A. Akslen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract A subset of breast cancer patients benefits from preoperative bevacizumab and chemotherapy, but validated predictive biomarkers are lacking. Here, we aimed to evaluate tissue-based angiogenesis markers for potential predictive value regardin
Externí odkaz:
https://doaj.org/article/c8a2b3892eea4e2a921d64ce837fe2d4
Autor:
Anand Khadse, Vilde D. Haakensen, Laxmi Silwal-Pandit, Julian Hamfjord, Patrick Micke, Johan Botling, Odd Terje Brustugun, Ole Christian Lingjærde, Åslaug Helland, Elin H. Kure
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Lung cancer is a common disease with a poor prognosis. Genomic alterations involving the KRAS gene are common in lung carcinomas, although much is unknown about how different mutations, deletions, and expressions influence the disease course. The fir
Externí odkaz:
https://doaj.org/article/add8e489bc4c4fa9b31afcd0d783f3bf
Autor:
Elen Kristine Höglander, Silje Nord, David C. Wedge, Ole Christian Lingjærde, Laxmi Silwal-Pandit, Hedda vdL Gythfeldt, Hans Kristian Moen Vollan, Thomas Fleischer, Marit Krohn, Ellen Schlitchting, Elin Borgen, Øystein Garred, Marit M. Holmen, Erik Wist, Bjørn Naume, Peter Van Loo, Anne-Lise Børresen-Dale, Olav Engebraaten, Vessela Kristensen
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-14 (2018)
Abstract Background Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular endothelial growth factor A (VEGFA) and inhibits its receptor interaction,
Externí odkaz:
https://doaj.org/article/5f928dd9e5634710814d56c306a83202
Autor:
Laxmi Silwal-Pandit, Hege Russnes, Elin Borgen, Veronica Skarpeteig, Hans Kristian Moen Vollan, Ellen Schlichting, Rolf Kåresen, Bjørn Naume, Anne-Lise Børresen-Dale, Marianne Farnebo, Anita Langerød
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139965 (2015)
WRAP53 protein controls intracellular trafficking of DNA repair proteins, the telomerase enzyme, and splicing factors. Functional loss of the protein has been linked to carcinogenesis, premature aging and neurodegeneration. The aim of this study was
Externí odkaz:
https://doaj.org/article/5bfd01a0e3c14f52bbb28cfffa97aba6
Autor:
Elin H. Kure, Janne Lehtiö, Bjørn S. Skålhegg, Knut Jørgen Labori, Ole Christian Lingjærde, Åslaug Helland, Daniel J. H. Nebdal, Astrid Marie Dalsgaard, Martina L. Skrede, Inger Marie B. Lothe, Georgios Mermelekas, Henrik J. Johansson, Stina M. Stålberg, Laxmi Silwal-Pandit
Pancreatic cancer remains a disease with unmet clinical needs and inadequate diagnostic, prognostic, and predictive biomarkers. In-depth characterization of the disease proteome is limited. This study thus aims to define and describe protein networks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377afbc6d590aa92c3ca9e611464e751
https://doi.org/10.1158/2767-9764.c.6550742
https://doi.org/10.1158/2767-9764.c.6550742
Autor:
Elin H. Kure, Janne Lehtiö, Bjørn S. Skålhegg, Knut Jørgen Labori, Ole Christian Lingjærde, Åslaug Helland, Daniel J. H. Nebdal, Astrid Marie Dalsgaard, Martina L. Skrede, Inger Marie B. Lothe, Georgios Mermelekas, Henrik J. Johansson, Stina M. Stålberg, Laxmi Silwal-Pandit
Supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001f7e5f61e0439d20aa20c2050e3b20
https://doi.org/10.1158/2767-9764.22544777.v1
https://doi.org/10.1158/2767-9764.22544777.v1
Autor:
Elin H. Kure, Janne Lehtiö, Bjørn S. Skålhegg, Knut Jørgen Labori, Ole Christian Lingjærde, Åslaug Helland, Daniel J. H. Nebdal, Astrid Marie Dalsgaard, Martina L. Skrede, Inger Marie B. Lothe, Georgios Mermelekas, Henrik J. Johansson, Stina M. Stålberg, Laxmi Silwal-Pandit
Univariate cox regression analysis (left) including clinical, pathological, and molecular variables. Multivariate cox regression analysis (right) including the variables with significant or trending association with patient survival in the univariate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a59666f24a88fb8e3e624d4266545f
https://doi.org/10.1158/2767-9764.22544762.v1
https://doi.org/10.1158/2767-9764.22544762.v1
Autor:
Elin H. Kure, Janne Lehtiö, Bjørn S. Skålhegg, Knut Jørgen Labori, Ole Christian Lingjærde, Åslaug Helland, Daniel J. H. Nebdal, Astrid Marie Dalsgaard, Martina L. Skrede, Inger Marie B. Lothe, Georgios Mermelekas, Henrik J. Johansson, Stina M. Stålberg, Laxmi Silwal-Pandit
Differential expression analysis of M2 and M4 proteins between PDAC and tumor adjacent tissue samples (Wilcoxon-rank sum test)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9110ce81ddd93a162b65b4421c4ad6
https://doi.org/10.1158/2767-9764.22544768
https://doi.org/10.1158/2767-9764.22544768