Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Laxmi Kumar Parajuli"'
Autor:
Laxmi Kumar Parajuli, Masato Koike
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2021)
Electron microscopy (EM)-based synaptology is a fundamental discipline for achieving a complex wiring diagram of the brain. A quantitative understanding of synaptic ultrastructure also serves as a basis to estimate the relative magnitude of synaptic
Externí odkaz:
https://doaj.org/article/c2339b645fc349ec8264b804940cc306
Publikováno v:
Cell Reports, Vol 10, Iss 2, Pp 162-169 (2015)
Competition between synapses contributes to activity-dependent refinement of the nervous system during development. Does local competition between neighboring synapses drive circuit remodeling during experience-dependent plasticity in the cerebral co
Externí odkaz:
https://doaj.org/article/6cca7c3ab7134e7187adc9759d59c518
Autor:
Usman Haider, Muhammad Hanif, Hiroki Kobayashi, Laxmi Kumar Parajuli, Daisuke Shimotoku, Ahmar Rashid, Sonia Safeer
Publikováno v:
2023 15th International Conference on Computer and Automation Engineering (ICCAE).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5980eb563b06558cb2c8c23a3584314a
https://doi.org/10.1109/iccae56788.2023.10111384
https://doi.org/10.1109/iccae56788.2023.10111384
Autor:
Tomoyuki Taguchi, Masanori Sawamura, Ryosuke Takahashi, Masashi Ikuno, Norihito Uemura, Jun Ueda, Junko Hara, Masato Koike, Shuichi Matsuzawa, Laxmi Kumar Parajuli, Katsutoshi Taguchi, Shinya Okuda, Etsuro Nakanishi, Masaki Tanaka, Takashi Ayaki, Maiko T. Uemura, Mari Hondo, Masashi Yanagisawa, Yusuke Hatanaka, Omar M. A. El-Agnaf, Hodaka Yamakado
Publikováno v:
Brain. 143:249-265
Parkinson’s disease is one of the most common movement disorders and is characterized by dopaminergic cell loss and the accumulation of pathological α-synuclein, but its precise pathogenetic mechanisms remain elusive. To develop disease-modifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79227075868fc1b4496b1fb2fee932fb
https://doi.org/10.1093/brain/awz380
https://doi.org/10.1093/brain/awz380
Autor:
Bruce E. Cohen, Parashar Thapa, Sebastian Fletcher-Taylor, Oscar Vivas, Rebecka J. Sepela, Robert Stewart, Mark Lillya, Laxmi Kumar Parajuli, Jon T. Sack, Karen Zito
Publikováno v:
Journal of General Physiology. 153
A primary goal of molecular physiology is to understand how conformational changes of proteins affect the function of cells, tissues, and organisms. Here, we describe an imaging method for measuring the conformational changes of the voltage sensors o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfaa3a88c4259d703f14ce68e0d5ea8a
https://doi.org/10.1085/jgp.202012858
https://doi.org/10.1085/jgp.202012858
Autor:
Laxmi Kumar Parajuli, Norihito Uemura, Yusuke Hatanaka, Masaki Tanaka, Hisako Akiyama, Kousaku Ohno, Masato Koike, Yoshio Hirabayashi, Katsumi Higaki, Ryosuke Takahashi, Hodaka Yamakado, Masashi Ikuno, Junko Hara, Katsutoshi Taguchi
Publikováno v:
Human Molecular Genetics. 28:1894-1904
Parkinson's disease (PD) is characterized by dopaminergic (DA) cell loss and the accumulation of pathological alpha synuclein (asyn), but its precise pathomechanism remains unclear, and no appropriate animal model has yet been established. Recent stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a034154215b484b2d7204c1a9bc58db5
https://doi.org/10.1093/hmg/ddz030
https://doi.org/10.1093/hmg/ddz030
Autor:
Laxmi Kumar Parajuli, Ken Wako, Soichiro Kakuta, Masato Koike, Masashi Ikuno, Hodaka Yamakado, Tomoyuki Taguchi, Ryosuke Takahashi, Suiki Maruo
Publikováno v:
eNeuro
The aging process is accompanied by various neurophysiological changes, and the severity of neurodegenerative disorders such as Parkinson’s disease increases with aging. However, the precise neuroanatomical changes that accompany the aging process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694e05947821940efcc2bb88262447f1
http://europepmc.org/articles/PMC7470930
http://europepmc.org/articles/PMC7470930
Publikováno v:
Biochemical and biophysical research communications. 530(1)
Neurons in the central nervous system display a great diversity of synaptic architecture. While much of our knowledge on the excitatory synapse morphology derives from the prototypical asymmetric synapses, little has been studied about the atypical c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbef5dbe2db99ca8db5dfc8b5820c48f
https://pubmed.ncbi.nlm.nih.gov/32828274
https://pubmed.ncbi.nlm.nih.gov/32828274
Autor:
Laxmi Kumar Parajuli
Publikováno v:
Juntendo Medical Journal. 64:386-391
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e95df5f755d99ede66a24c08081dcaa
https://doi.org/10.14789/jmj.2018.64.jmj18-ln03
https://doi.org/10.14789/jmj.2018.64.jmj18-ln03
Publikováno v:
Brain Research Bulletin. 129:3-11
Principal neurons in multiple brain regions receive a vast majority of excitatory synaptic contacts on the tiny dendritic appendages called dendritic spines. These structures are believed to be the locus of memory storage in the brain. Indeed, neurol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c1bb2548de5bddf22a4e5601d9c813
https://doi.org/10.1016/j.brainresbull.2016.07.014
https://doi.org/10.1016/j.brainresbull.2016.07.014