Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Laxmi Adhikary"'
Autor:
Subhankar P. Mandal, Aakriti Garg, P. Prabitha, Ashish D. Wadhwani, Laxmi Adhikary, B. R. Prashantha Kumar
Publikováno v:
Chemistry Central Journal, Vol 12, Iss 1, Pp 1-21 (2018)
Abstract Background An alarming requirement for finding newer antidiabetic glitazones as agonists to PPARγ are on its utmost need from past few years as the side effects associated with the available drug therapy is dreadful. In this context, herein
Externí odkaz:
https://doaj.org/article/2c1e7dfb84b048c799bb6b36fb235684
Autor:
Stefano Colombo, Alicia Alonso, Rebeca Real, Roshan Goswami, Maria Carmen Suarez, Samuel Ogueta, Margarida Almeida, Laxmi Adhikary, Mónica G. Malmierca, Ivan S. de Melo
Publikováno v:
Process Biochemistry. 125:130-140
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebf6a1a0cce0ecc06a2a1b7fd3803fe4
https://doi.org/10.1016/j.procbio.2022.12.013
https://doi.org/10.1016/j.procbio.2022.12.013
Autor:
Arnab Bera, Jeffrey Smith, Bhavesh Vats, Daniel J. Ranayhossaini, Rajesh Ullanat, H. Pai, Gaurav R Mehta, Pradeep Kabadi, Ankita Singh, Praveen Reddy Moole, Abhilashi Sahu, Ramakrishnan Melarkode, Maninder Kaur, Malini Subbarao, Parag Goyal, Laxmi Adhikary, Jyoti Iyer, Shankara Gouda, Arindam Saha, Ashwani Marwah
Publikováno v:
Future Medicinal Chemistry. 13:1531-1557
Aims: Preclinical comparative similarity studies of trastuzumab-dkst, a Herceptin® biosimilar, are reported. Materials & methods: Primary sequence and higher order structure and pharmacological mechanisms of action were compared using multiple techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8564398914d00ad5e5deb9eb84a59c3f
https://doi.org/10.4155/fmc-2021-0113
https://doi.org/10.4155/fmc-2021-0113
Autor:
Praveen Kallamvalliillam Sankaran, Dinesh V. Palanivelu, Chethan Gejjalagere Honnappa, Laxmi Adhikary, Pradeep Kabadi, H. Pai, Malini Subbarao
Publikováno v:
Journal of Chromatography B. :83-95
Modern analytical ion-exchange chromatography is one of the conventional tools used for assessment of product-related quality attributes in bio-therapeutic monoclonal antibodies (mAbs). Here, we present an approach to resolve, identify, and quantify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28385c61a40bdacd0bb185019a8d7eb
https://doi.org/10.1016/j.jchromb.2018.10.019
https://doi.org/10.1016/j.jchromb.2018.10.019
Autor:
Laxmi Adhikary, Ashish Wadhwani, Subhankar P. Mandal, Aakriti Garg, B. R. Prashantha Kumar, P. Prabitha
Publikováno v:
Chemistry Central Journal, Vol 12, Iss 1, Pp 1-21 (2018)
Chemistry Central Journal
Chemistry Central Journal
Background An alarming requirement for finding newer antidiabetic glitazones as agonists to PPARγ are on its utmost need from past few years as the side effects associated with the available drug therapy is dreadful. In this context, herein, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef88db01b0fa58e149b0f490d9ca631
http://link.springer.com/article/10.1186/s13065-018-0508-0
http://link.springer.com/article/10.1186/s13065-018-0508-0
Autor:
Clea Solís, Koen Sandra, Daniel Sacristán, Laxmi Adhikary, Isabel Vandenheede, Marie-Elise Beydon, Alexia Ortiz, Isabel Ruppen
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 77
The majority of recombinant mAb products contain heterogeneous charge variants, commonly the result of post-translational modifications occurring during cell culture and accumulated during production, formulation and storage. MB02 is a biosimilar mAb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7afee8362edcd1b2ceaa07ac12ffd5f1
https://pubmed.ncbi.nlm.nih.gov/35667958
https://pubmed.ncbi.nlm.nih.gov/35667958
Autor:
Merugumolu Vijay Kumar, Laxmi Adhikary, T. Ashok, Antony Justin, Revanasiddappa Bistuvalli Chandrashekarappa, Syed Faizan, Nulgumnalli Manjunathaiah Raghavendra, Namburu Lalitha Naishima, B. R. Prashantha Kumar, Pradeep Kabadi
Publikováno v:
Bioorganic Chemistry. 117:105462
Biginelli 1,4-dihydropyrimidines are extensively screened for their potential anticancer activity in the last decade. In this context, a series of Biginelli 1,4-dihydropyrimidines were designed and synthesised using PTSA as an efficient catalyst. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa91262705625217115ecbf0431f793
https://doi.org/10.1016/j.bioorg.2021.105462
https://doi.org/10.1016/j.bioorg.2021.105462
Autor:
Praveen Kallamvalliillam Sankaran, Dinesh V. Palanivelu, Anand Khedkar, Pradeep Kabadi, Amarnath Chatterjee, Laxmi Adhikary
Publikováno v:
Journal of the American Society for Mass Spectrometry. 27:1677-1685
We present here extensive mass spectrometric studies on the formation of a Tris conjugate with a therapeutic monoclonal antibody. The results not only demonstrate the reactive nature of the Tris molecule but also the sequence and reaction conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7f24664483c76280fee82f08e21b16
https://doi.org/10.1007/s13361-016-1447-4
https://doi.org/10.1007/s13361-016-1447-4
Publikováno v:
Synthetic Communications. 42:3089-3096
We report facile and efficient conversion of the amino functional group of amino acids such a s L-tyrosine, DL-phenylalanine, and glycine to the corresponding (±)-2-thioxo-thiazolidine-4-ones (rhodanines). Stereospecific synthesis of amino acid–in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85227ad21cb65cbf9443b2209240f973
https://doi.org/10.1080/00397911.2011.576322
https://doi.org/10.1080/00397911.2011.576322
Autor:
B. R. Prashantha Kumar, Laxmi Adhikary, Mukesh Soni, R. B. Nasir Baig, Mohan Patil, Sudershan Kumar, Kuldeep Singh
Publikováno v:
European Journal of Medicinal Chemistry. 46:835-844
Three series of novel glitazones were designed and prepared by using appropriate synthetic schemes to incorporate glycine, aromatic and alicyclic amines via two carbon linker. Compounds were synthesized both under conventional and microwave methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35664888e44f7482355bccabbd9f389
https://doi.org/10.1016/j.ejmech.2010.12.019
https://doi.org/10.1016/j.ejmech.2010.12.019