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of 11
pro vyhledávání: '"Laxman J. Patel"'
Autor:
Mehul M. Patel, Laxman J. Patel
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
Objective. Quinolone moiety is an important class of nitrogen containing heterocycles widely used as key building blocks for medicinal agents. It exhibits a wide spectrum of pharmacophores and has bactericidal, antiviral, antimalarial, and anticancer
Externí odkaz:
https://doaj.org/article/0b78e3a8774e438f972e0ead9bf9a2dc
Autor:
Pratik G. Modh, Laxman J. Patel
Publikováno v:
Research Journal of Pharmacy and Technology. :4226-4229
Diabetes mellitus is a metabolic condition characterised by chronic hyperglycaemia, and type II diabetes is the most common type, accounting for 90% of cases globally. Hyperglycaemia is major complication of Diabetes mellitus. Postprandial hyperglyca
Publikováno v:
Journal of Pharmaceutical Research International. :68-79
Aim: Novel quinazolin-4(3H)-one heterocycles were synthesized and assessed for their anti-diabetic activity. Non-enzymatic glycosylation of haemoglobin assay was carried out to identify their potential as anti-diabetic. The cyclization of quinazolino
Autor:
Laxman J. Patel, Suleman S. Khoja
Publikováno v:
Journal of Pharmaceutical Research International. :194-204
Ertugliflozin and Sitagliptin is combination of Antidiabetic drug in tablet Steglujan 15 mg/100 mg film-coated tablets®, a member Antidiabetic drug, is a recent drug developed by Merck Sharp and Dohme Company for the treatment of Type 2 diabetes. Er
Autor:
Laxman J. Patel, Pratik G. Modh
Publikováno v:
Journal of Pharmaceutical Research International. :81-92
Aim: A series of novel quinazolinone derivates was synthesized and assessed for their ability to inhibitory action on pancreatic lipase. The cyclization of quinazolinone-4(3H)-one derivatives was achieved, whereas carbon-carbon cross coupling reactio
Autor:
Laxman J. Patel, Suleman S. Khoja
Publikováno v:
Indo Global Journal of Pharmaceutical Sciences. 11:62-69
Autor:
Laxman J. Patel, Mehul Patel
Publikováno v:
Current drug discovery technologies. 14(4)
BACKGROUND Quinolone scaffolds are widely used for the synthesis of a number of medicinal compounds with variety of biological activity. In view of the reported antimicrobial activity of various fluoroquinolones, the structure activity studies of var
Autor:
Laxman J. Patel, Mehul Patel
Publikováno v:
The Scientific World Journal
The Scientific World Journal, Vol 2014 (2014)
The Scientific World Journal, Vol 2014 (2014)
Objective. Quinolone moiety is an important class of nitrogen containing heterocycles widely used as key building blocks for medicinal agents. It exhibits a wide spectrum of pharmacophores and has bactericidal, antiviral, antimalarial, and anticancer
Autor:
Laxman J. Patel, Rasikkumar M. Ravani
Publikováno v:
International Journal of Pharmaceutical Sciences and Drug Research. 8
Synthesis of novel quinazoline derivatives was performed from reaction of N-benzoyl substituted piperazine-1carbothioamide with 4-(2-chlormethyl) quinazoline-4-yloxy phenyl benzamide derivatives and screened for their in vitro cytotoxic activity by M
Publikováno v:
Journal of AOAC INTERNATIONAL. 90:1242-1249
A simple, precise, and rapid stability-indicating reversed-phase column liquid chromatographic (RP-LC) method has been developed and subsequently validated for simultaneous estimation of simvastatin (SIM) and ezetimibe (EZE) from their combination dr