Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Lawrence Weir"'
Publikováno v:
BMJ. :n340
Angus Howard Weir Bain was the son and brother of general practitioners. He was educated at Epsom College. On qualifying he completed national service as a captain in the Royal Army Medical Corps in Egypt. He did house physician and house surgeon rol
Autor:
Bain, Lawrence Weir
Publikováno v:
The British Medical Journal, 1938 Feb . 1(4025), 484-484.
Externí odkaz:
https://www.jstor.org/stable/25369061
Autor:
Mike Pyne, Paul B. Robbins, Robert R. Becklin, Kartika Widjaja, Shuping Lai, Sam Thompson, Lawrence Weir, J. Jay Boniface, Yew-Seng J. Ho, John M. Peltier, Moritz von Rechenberg, Cindy Lou Chepanoske, Peter J. Sheffield, Srdjan Askovic, Yuejun Zhen, Justin Savage, Vladimir Kery, Bonnie Richardson, Nafei Xu, Tahmina Mujtaba
Publikováno v:
International Journal of Mass Spectrometry. 238:119-130
Proteomics-based technologies have the potential to accelerate the development of drugs, but such technologies must be well integrated in order to have a positive impact. We describe, herein, a multi-step process for the discovery of protein–protei
Autor:
J M Isner, Sigrid Nikol, Marianne Kearney, Berthold Höfling, J G Pickering, N Murakami, Guy Leclerc, Lawrence Weir
Publikováno v:
Atherosclerosis. 130:71-85
Intimal proliferation and functional changes involving vascular smooth muscle cells are key events in the development of atherosclerosis, including restenosis after percutaneous transluminal angioplasty. Nonmuscle myosin (NMM) is required for cytokin
Autor:
Ann Pieczek, Jeffrey M. Isner, Jason A. Lowry, Kenneth Walsh, Edi Brogi, James F. Symes, Satoshi Takeshita, Kenneth Rosenfield, Lawrence Weir, Dan Jurayj
Publikováno v:
Human Gene Therapy. 7:959-988
The age-adjusted prevalence of peripheral arterial disease (PAD) in the U.S. population has been estimated to approach 12%. The clinical consequences of occlusive peripheral arterial disease (PAD) include pain on walking (claudication), pain at rest,
Autor:
Kenneth Walsh, Robert M. Schainfeld, Jason A. Lowry, Satoshi Takeshita, Lawrence Weir, Jeffrey M. Isner, Edi Brogi, Susan Rossow, Kenneth Rosenfield, Ann Pieczek, James F. Symes
Publikováno v:
Circulation. 91:2687-2692
Peripheral Artery Disease: Primary Pharmacological Therapy Is Ineffective for Patients With Critical Limb Ischemia The prognosis for patients with chronic critical leg ischemia, ie, rest pain and/or established lesions that jeopardize the integrity o
Autor:
Douglas W. Losordo, Guy Leclerc, Jeffrey M. Isner, Satoshi Takeshita, Lawrence Weir, J G Pickering, J Jekanowski, Marianne Kearney, Dov Gal
Publikováno v:
Circulation. 89:785-792
BACKGROUND The development of molecular strategies for the treatment of restenosis has been hindered by low efficiencies of in vivo arterial transfection. Expression of intracellular marker proteins is generally evident in < 1% of vascular smooth mus
Autor:
J. Geoffrey Pickering, Marianne Kearney, Lawrence Weir, Christophe Bauters, Sigrid Nikol, Jeffrey M. Isner, Guy Leclerc, Reimer Riessen
Publikováno v:
Trends in cardiovascular medicine. 4(5)
Directional atherectomy has provided the opportunity to study the pathology of restenosis in human tissue specimens from live patients. The restenosis lesion is characterized by two distinctive features: a focus of hypercellularity, comprised of cell
Autor:
Lawrence Weir, Donald S. Baim, Jeffrey M. Isner, Michael Simons, Guy Leclerc, Robert D. Safian
Publikováno v:
New England Journal of Medicine. 328:608-613
Neointimal proliferation leading to restenosis frequently develops after coronary angioplasty. This process is associated with a change in vascular smooth-muscle cells from a contractile (quiescent) phenotype to a synthetic or proliferating (activate
Publikováno v:
Journal of Clinical Investigation. 91:724-729
Smooth muscle cell proliferation in the intima of arteries is a principal event associated with vascular narrowing after balloon angioplasty and bypass surgery. Techniques for limiting smooth muscle cell proliferation, however, have not as yet yielde