Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lawrence Wayne Torley"'
Autor:
Michael P. Trova, Suresh S. Kerwar, Walter C. Pickett, Constance Kohler, Robert E. Schaub, Allan Wissner, Lawrence Wayne Torley, Marion L. Carroll
Publikováno v:
Journal of Medicinal Chemistry. 36:580-590
A series of platelet activating factor (PAF) antagonists containing a quaternary pyridinium ring connected through an amide, imide, or carbamate linkage to a substituted aromatic ring was prepared. Of these compounds, those containing a branched imid
Autor:
James Joseph Gibbons, Susan Quinn Dejoy, Narendra R. Desai, Lawrence Wayne Torley, Walter C. Pickett, S. S. Kerwar, Arnold L. Oronsky
Publikováno v:
Critical Care Medicine. 20:1448-1453
Background and methods In murine models of endotoxemia, large amounts of lipopolysaccharide have to be administered to induce mortality. If mice are pretreated with D-galactosamine, the amount of lipopolysaccharide required to induce mortality is sig
Autor:
Suresh S. Kerwar, Lawrence Wayne Torley, Constance Kohler, Marion L. Carroll, Allan Wissner, Walter C. Pickett, S Wrenn, Robert E. Schaub, K E Green
Publikováno v:
Journal of Medicinal Chemistry. 35:1650-1662
A series of aryl phosphoglyceride (3, 19-61) and bis-aryl phosphate (67-135) antagonists of platelet activating factor (PAF) were prepared. A group of four bifunctional phosphorus reagents (5a-c and 7) were developed that allowed the preparation of t
Autor:
Kenneth H. Grabstein, Robert Jeyaseelan, Michael M. Wick, Susan Quinn Dejoy, Lawrence Wayne Torley, June Eisenmann, William E. Munger, Ray Paxton, S. S. Kerwar, Tom Cox
Publikováno v:
Cellular immunology. 165(2)
Interleukin-15 is a new cytokine that stimulates the proliferation of T cells and other cells of the immune system. Some of the biological properties of interleukin-15 overlap that of interleukin-2. Using murine models, the present studies have shown
Autor:
Michael P. Trova, Allan Wissner, Bernard Dean Johnson, Walter C. Pickett, Lawrence Wayne Torley, Robert E. Schaub, Marion L. Carroll, Suresh S. Kerwar, Constance Kohler
Publikováno v:
Journal of medicinal chemistry. 35(26)
A series of bis-aryl amide (13-57 and 66-81) and bis-aryl urea (58 and 85) antagonists of platelet-activating factor (PAF) was prepared that contain, separating the two aromatic rings, linear amide linkages of the form -(CH2)nCONH- (n = 0-2), -OCH2CO