Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lawrence W. Kaler"'
Autor:
Lawrence W. Kaler, William B. Neaves
Publikováno v:
The Anatomical Record. 192:513-518
Existing evidence suggests that the aging human male experiences a gradual decline in testosterone production, a phenomenon that should be reflected in the Leydig cell population of the testis. It has been proposed that Leydig cells diminish in numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34626f050dab79d96a9b1f511700c174
https://doi.org/10.1002/ar.1091920405
https://doi.org/10.1002/ar.1091920405
Publikováno v:
Neuroendocrinology. 41:357-362
The purpose of this study was to determine the effects of destroying somatostatin (SRIF) neurons of the periventricular (PV) nucleus of the hypothalamus on the pulsatile pattern of growth hormone (GH) secretion in female rats. At 6-10 days after plac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d50178541734a336c6d9446fa7010a9
https://doi.org/10.1159/000124202
https://doi.org/10.1159/000124202
Publikováno v:
Endocrinology. 119:566-571
Whether the rhesus male experiences changes in the dynamics of testosterone (T) and LH secretion with age was investigated in six young (6-8 yr old; 7-12 kg) and six aged (22+ yr old; 9-11 kg) intact rhesus males. Each male was fitted with an indwell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a76e1b4bf0c628c3fe1f55da071c969
https://doi.org/10.1210/endo-119-2-566
https://doi.org/10.1210/endo-119-2-566
Publikováno v:
Brain Research. 311:370-374
These studies examined the effects of surgical interruption of anterolateral neural connections of the medial basal hypothalamus (MBH) on the subsequent ability of the perifused anterior pituitary (AP) to release prolactin (Prl). Anterolateral MBH cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad07ad8a6f9d0e7db84da25684ca066
https://doi.org/10.1016/0006-8993(84)90103-3
https://doi.org/10.1016/0006-8993(84)90103-3
Publikováno v:
Endocrinology. 119:1281-1284
Enhanced nocturnal release of GH is decreased with aging in man, a change that may implicate GH in a general decline in anabolic metabolism associated with aging. The aim of this study was to determine whether nonhuman primates experience an age-rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219e2c86325cc0d353c86245436d5af5
https://doi.org/10.1210/endo-119-3-1281
https://doi.org/10.1210/endo-119-3-1281
Publikováno v:
Neurobiology of Aging. 7:121-125
We studied the capability of hypothalamic tissue from young (3–4 months) and old (22–24 months) male rats to aromatize androgens to estrogens. Aromatase activity was measured in homogenates of brain tissue by using a radiometric assay that quanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab032f325b1ec4ad1d5ed659b4b314c0
https://doi.org/10.1016/0197-4580(86)90150-8
https://doi.org/10.1016/0197-4580(86)90150-8
Autor:
Lawrence W. Kaler, Vaughn Critchlow
Publikováno v:
Mechanisms of Ageing and Development. 25:103-115
The possibility that the gonadotrope population of the anterior pituitary experiences an age-related alteration in function was investigated by in vivo and in vitro methods in young (4- to 6-month) and old (18- to 20-month) male Sprague-Dawley rats.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88dab6def746cc29a3529f66488a08a
https://doi.org/10.1016/0047-6374(84)90133-7
https://doi.org/10.1016/0047-6374(84)90133-7
Autor:
William B. Neaves, Lawrence W. Kaler
Publikováno v:
Endocrinology. 108(2)
In male Sprague-Dawley rats between 3-24 months of age, plasma concentrations of testosterone declined by more than 50% while concentrations of LH in plasma remained relatively constant. During the same interval, body weight rose almost 50%, suggesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f49df302da56296ad658838c7d9f48
https://pubmed.ncbi.nlm.nih.gov/7449746
https://pubmed.ncbi.nlm.nih.gov/7449746
Publikováno v:
Brain research. 386(1-2)
Hypothalamic periventricular (PV) nucleus lesions reduce median eminence (ME) SRIF content by approximately equal to 80% without affecting non-stress plasma growth hormone (GH) levels or the GH response to stress. Our aim was to study the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0bf4455208d27c5511bcf3ac1f4a4ee
https://pubmed.ncbi.nlm.nih.gov/2877715
https://pubmed.ncbi.nlm.nih.gov/2877715
Autor:
William B. Neaves, Lawrence W. Kaler
Publikováno v:
Journal of gerontology. 36(4)
Factors bearing on the steroidogenic capacity of the aging testis have been examined in Sprague-Dawley rats between 3 and 24 months of age. Neither the number nor the binding affinity of testicular receptors for 125I-hCG changed with age. The ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988b6cad95e7866de65b32dc53e78750
https://pubmed.ncbi.nlm.nih.gov/7252069
https://pubmed.ncbi.nlm.nih.gov/7252069