Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Lawrence T. Sennello"'
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 571:199-208
A sensitive method for the simultaneous high-performance liquid chromatographic determination of clarithromycin and its active metabolite in plasma and urine is described. Alkalinized samples were coextracted with an internal standard and analyzed on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3989053ac3d47a76328d988429fcf5f
https://doi.org/10.1016/0378-4347(91)80446-j
https://doi.org/10.1016/0378-4347(91)80446-j
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 229:149-157
A simple and very precise high-performance liquid chromatographic procedure has been developed for the determination of cefmenoxime, a new broad spectrum cephalosporin antibiotic, in plasma. The workup procedure involves ultrafiltration of samples wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2174e508fce6aad5214514b1ebe264b6
https://doi.org/10.1016/s0378-4347(00)86046-6
https://doi.org/10.1016/s0378-4347(00)86046-6
Publikováno v:
Journal of International Medical Research. 7:253-262
Two clinical studies were conducted to study the pharmacokinetics of alclofenac in healthy adult male volunteers when the drug was administered in both single and multiple dosing regimens. The first study involved the participation of thirty-two subj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0573881c5f62311d08bdaa7b75c9e85f
https://doi.org/10.1177/030006057900700401
https://doi.org/10.1177/030006057900700401
Autor:
Lawrence T. Sennello, Fred E. Kohn
Publikováno v:
Analytical Chemistry. 46:752-755
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712fbbc88a060aac8a42664328dca036
https://doi.org/10.1021/ac60342a051
https://doi.org/10.1021/ac60342a051
Publikováno v:
Journal of Pharmaceutical Sciences. 70:990-994
Abstract A radioimmunoassay for the direct measurement of carteolol, a new @-adrenoreceptor blocker, in human plasma was developed. Car- teolol was acylated to form 0-glutarylcarteolol, which was conjugated to bovine serum albumin to provide the immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b38b8bc1e12c3f459b537da877dc56f
https://doi.org/10.1002/jps.2600700905
https://doi.org/10.1002/jps.2600700905
Autor:
Elizabeth W Thomas, Robert C. Sonders, G. Richard Granneman, Lawrence T. Sennello, Beverly Wynne
Publikováno v:
Clinical Pharmacology and Therapeutics. 31:95-103
We evaluated cefsulodin kinetics in normal subjects after 250-, 500-, and 1,000-mg, intramuscular injections and 500-, 1,000-, and 2,000-mg 30-min intravenous infusions. Twelve plasma and four urine samples were collected in the first 12 and 24 hr. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bde266d5b4ad956cfea7e703ec0dd0
https://doi.org/10.1038/clpt.1982.15
https://doi.org/10.1038/clpt.1982.15
Publikováno v:
Clinical Pharmacology & Therapeutics. 23:414-420
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fad1ffcbc35d0aad09c1aff3ed1842
https://doi.org/10.1002/cpt1978234414
https://doi.org/10.1002/cpt1978234414
Autor:
Lawrence T. Sennello
Publikováno v:
Biochemical Medicine. 8:345-351
A gas chromatographic procedure is described which permits quantification of dichloroacetic acid in urine or plasma to a lower limit of about 0.04 μg/ml. Preliminary data are given to suggest that the method should be equally applicable to the deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c06465ce3d08ec4fbd691d3c2a3eff
https://doi.org/10.1016/0006-2944(73)90039-2
https://doi.org/10.1016/0006-2944(73)90039-2
Publikováno v:
Clinical Pharmacology and Therapeutics. 31:602-608
Cefsulodin kinetics were determined after a 500-mg dose to normal subjects and patients with varying degrees of renal insufficiency, including those requiring hemodialysis. Elimination kinetics were described by a two-compartment model. Steady-state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e6a539c84f3458f8ed725e8783bb90d
https://doi.org/10.1038/clpt.1982.84
https://doi.org/10.1038/clpt.1982.84
Publikováno v:
Journal of Pharmaceutical Sciences. 71:1112-1115
A simple and precise high-performance liquid chromatographic (HPLC) procedure was developed for the determination of cefsulodin, a new antipseudomonal cephalosporin antibiotic, in plasma. The analytical procedure involved ultrafiltration of samples t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0223cd8c2e0793afd781bdc03674632
https://doi.org/10.1002/jps.2600711008
https://doi.org/10.1002/jps.2600711008