Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lawrence T. Park"'
Autor:
Ruin Moaddel, Cristan A. Farmer, Mani Yavi, Bashkim Kadriu, Min Zhu, Jinshui Fan, Qinghua Chen, Elin Lehrmann, Giovanna Fantoni, Supriyo De, Caio H. Mazucanti, Elia E. Acevedo-Diaz, Peixiong Yuan, Todd D. Gould, Lawrence T. Park, Josephine M. Egan, Luigi Ferrucci, Carlos A. Zarate, Jr.
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108527- (2023)
Summary: Ketamine is a treatment for both refractory depression and chronic pain syndromes. In order to explore ketamine’s potential mechanism of action and whether ketamine or its metabolites cross the blood brain barrier, we examined the pharmaco
Externí odkaz:
https://doaj.org/article/dd7ad1b3a925423d97ebe742d4f5433a
Autor:
Ruin Moaddel, Panos Zanos, Cristan A. Farmer, Bashkim Kadriu, Patrick J. Morris, Jacqueline Lovett, Elia E. Acevedo-Diaz, Grace W. Cavanaugh, Peixiong Yuan, Mani Yavi, Craig J. Thomas, Lawrence T. Park, Luigi Ferrucci, Todd D. Gould, Carlos A. Zarate
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Subanesthetic-dose racemic (R,S)-ketamine (ketamine) produces rapid, robust, and sustained antidepressant effects in major depressive disorder (MDD) and bipolar disorder (BD) and has also been shown to effectively treat neuropathic pain, com
Externí odkaz:
https://doaj.org/article/a822b41b1e6245a389bcef25692869af
Publikováno v:
BMC Psychiatry, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Despite decades of research, the rate of death from suicide is rising in the United States. Suicide is a complex and multifactorial phenomenon and, to date, no validated biomarkers that predict suicidal behavior have been identifi
Externí odkaz:
https://doaj.org/article/26da532345c144b28af233ce0d3ca8c7
Autor:
Brandi Quintanilla, Gustavo C. Medeiros, Dede Greenstein, Peixiong Yuan, Jenessa N. Johnston, Lawrence T. Park, Fernando S. Goes, Todd D. Gould, Carlos A. Zarate
Publikováno v:
Journal of Clinical Psychopharmacology. 43:89-96
Autor:
Jenessa N. Johnston, Maximillian S. Greenwald, Ioline D. Henter, Christoph Kraus, Anahit Mkrtchian, Neil G. Clark, Lawrence T. Park, Philip Gold, Carlos A. Zarate, Bashkim Kadriu
Publikováno v:
Drug Discovery Today. 28:103518
Publikováno v:
Discover Mental Health. 2
This manuscript reviews the clinical evidence regarding single-dose intravenous (IV) administration of the novel glutamatergic modulator racemic (R,S)-ketamine (hereafter referred to as ketamine) as well as its S-enantiomer, intranasal esketamine, fo
Autor:
Ruin Moaddel, Panos Zanos, Cristan A. Farmer, Bashkim Kadriu, Patrick J. Morris, Jacqueline Lovett, Elia E. Acevedo-Diaz, Grace W. Cavanaugh, Peixiong Yuan, Mani Yavi, Craig J. Thomas, Lawrence T. Park, Luigi Ferrucci, Todd D. Gould, Carlos A. Zarate
Publikováno v:
Translational psychiatry. 12(1)
Subanesthetic-dose racemic (R,S)-ketamine (ketamine) produces rapid, robust, and sustained antidepressant effects in major depressive disorder (MDD) and bipolar disorder (BD) and has also been shown to effectively treat neuropathic pain, complex regi
Publikováno v:
CNS drugs. 36(2)
Autor:
Nadia S. Hejazi, Cristan A. Farmer, Mark Oppenheimer, Tolulope B. Falodun, Lawrence T. Park, Wallace C. Duncan, Carlos A. Zarate
Publikováno v:
J Psychiatr Res
The Hamilton Depression Rating Scale (HDRS), which includes several insomnia-related items, is potentially valuable in evaluating both depressive and sleep symptoms. However, the HDRS insomnia items have not been fully assessed by objective measures.
Autor:
Elizabeth D. Ballard, Cristan A. Farmer, Jessica Gerner, Bartholt Bloomfield-Clagett, Lawrence T. Park, Carlos A. Zarate
Publikováno v:
J Affect Disord
BACKGROUND: Early markers preceding suicide ideation (SI) may provide valuable information for both assessment and treatment. The glutamatergic modulator ketamine has rapid, transient effects on SI, creating an opportunity to observe potential antece