Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Lawrence T. McGrath"'
Autor:
Lana J. Dixon, G. Dennis Johnston, Lawrence T. McGrath, Naglaa A. El-Sherbeeny, Paul Hamilton, William J. Leahey, C G Hanratty, David R. Morgan, Gary E. McVeigh
Publikováno v:
The American Journal of Cardiology. 97:547-551
We investigated the effects of omega-3 fatty acids administration on endothelium-dependent vasodilation in patients > or =65 years old who received treatment for chronic heart failure (CHF). Twenty patients (mean age 73 years; 15 men) with grade II a
Publikováno v:
Annals of the New York Academy of Sciences. 1019:392-395
Glutathione and glutathione peroxidase activity are important components in the complex body defense against oxidative damage. In this study, we have measured malondialdehyde (MDA) as a marker of oxidative stress, the antioxidant glutathione (GSH), a
Autor:
Adrian Devine, David R. Morgan, William J. Leahey, Naglaa A. El-Sherbeeny, Sinead M. Hughes, G. Dennis Johnston, Gary E. McVeigh, Lana J. Dixon, Richard Plumb, Lawrence T. McGrath
Publikováno v:
Circulation. 107:1725-1728
Background— Impaired endothelium-mediated vasodilatation (EMVD) in congestive cardiac failure (CCF) has been linked to decreased nitric oxide (NO) bioavailability because of its interaction with vascular superoxide (O 2 ·− ), derived predominant
Autor:
Adrian Devine, C G Hanratty, Lawrence T. McGrath, David G.A. Morgan, Lana J. Dixon, Martin Wilson, Gary E. McVeigh, Paul Hamilton, William J. Leahey
Publikováno v:
Circulation. 106:208-213
Background — The therapeutic benefits that accompany the continuous administration of organic nitrates are attenuated by the development of tolerance to the compounds. Altered superoxide production and NO bioavailability have been implicated in con
Publikováno v:
Heart. 85:326-330
BACKGROUND—Raised homocysteine is a risk factor for vascular disease. Homocysteine is formed from methionine, and dietary manipulation of homocysteine in primates and humans with oral methionine is associated with endothelial dysfunction. A cause-e
Publikováno v:
Clinica Chimica Acta. 264:1-12
The major cause of death following transplantation is cardiovascular disease. Among the many processes involved in atherogenesis, oxidative stress and modification of low density lipoprotein has been assigned a major role. This in turn may be affecte
Publikováno v:
Irish Journal of Medical Science. 164:289-292
Two fluorescent probes were used for the measurement of membrane fluidity in patients on haemodialysis and continuous ambulatory peritoneal dialysis. 1,6-Diphenyl-1,3,5-hexatriene (DPH) anisotropy gives an indication of lipid order and pyrene measure
Autor:
A F Douglas, E. McClean, G. P. R. Archbold, G. D. Johnston, Lawrence T. McGrath, J. H. Brown, C. C. Doherty
Publikováno v:
Clinica Chimica Acta. 235:179-188
Oxidative damage due to free radical production is increased in uraemic patients and has been suggested as a possible factor contributing to the anaemia of chronic renal failure (CRF) and the pathogenesis of atherosclerosis. Oxidative stress was asse
Autor:
J. R. Hayes, W. R. Henry, Lawrence T. McGrath, G D Johnston, Geraldine M. Brennan, B. J. McDermott, Gary E. McVeigh, J. W. Andrews
Publikováno v:
Diabetologia. 35:771-776
The endothelium plays a pivotal role in modulating the reactivity of vascular smooth muscle through the formation of several vasoactive substances. We examined the effects of endothelium-dependent and independent vasodilators on forearm blood flow in
Autor:
Robert J. Elliott, Lawrence T. McGrath
Publikováno v:
Atherosclerosis. 87:211-220
The smooth muscle cell invasion and macrophage stimulation within the intima during prolonged exposure to high blood levels of cholesterol esters contribute to increased production of connective tissue matrix. The thickened intima in turn immobilisin