Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lawrence T, Park"'
Autor:
Ruin Moaddel, Cristan A. Farmer, Mani Yavi, Bashkim Kadriu, Min Zhu, Jinshui Fan, Qinghua Chen, Elin Lehrmann, Giovanna Fantoni, Supriyo De, Caio H. Mazucanti, Elia E. Acevedo-Diaz, Peixiong Yuan, Todd D. Gould, Lawrence T. Park, Josephine M. Egan, Luigi Ferrucci, Carlos A. Zarate, Jr.
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108527- (2023)
Summary: Ketamine is a treatment for both refractory depression and chronic pain syndromes. In order to explore ketamine’s potential mechanism of action and whether ketamine or its metabolites cross the blood brain barrier, we examined the pharmaco
Externí odkaz:
https://doaj.org/article/dd7ad1b3a925423d97ebe742d4f5433a
Autor:
Ruin Moaddel, Panos Zanos, Cristan A. Farmer, Bashkim Kadriu, Patrick J. Morris, Jacqueline Lovett, Elia E. Acevedo-Diaz, Grace W. Cavanaugh, Peixiong Yuan, Mani Yavi, Craig J. Thomas, Lawrence T. Park, Luigi Ferrucci, Todd D. Gould, Carlos A. Zarate
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Subanesthetic-dose racemic (R,S)-ketamine (ketamine) produces rapid, robust, and sustained antidepressant effects in major depressive disorder (MDD) and bipolar disorder (BD) and has also been shown to effectively treat neuropathic pain, com
Externí odkaz:
https://doaj.org/article/a822b41b1e6245a389bcef25692869af
Publikováno v:
BMC Psychiatry, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Despite decades of research, the rate of death from suicide is rising in the United States. Suicide is a complex and multifactorial phenomenon and, to date, no validated biomarkers that predict suicidal behavior have been identifi
Externí odkaz:
https://doaj.org/article/26da532345c144b28af233ce0d3ca8c7
Autor:
Brandi Quintanilla, Gustavo C. Medeiros, Dede Greenstein, Peixiong Yuan, Jenessa N. Johnston, Lawrence T. Park, Fernando S. Goes, Todd D. Gould, Carlos A. Zarate
Publikováno v:
Journal of Clinical Psychopharmacology. 43:89-96
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efe5ee2894d57866712e6dd111c8a6f8
https://doi.org/10.1097/jcp.0000000000001663
https://doi.org/10.1097/jcp.0000000000001663
Autor:
Jenessa N. Johnston, Maximillian S. Greenwald, Ioline D. Henter, Christoph Kraus, Anahit Mkrtchian, Neil G. Clark, Lawrence T. Park, Philip Gold, Carlos A. Zarate, Bashkim Kadriu
Publikováno v:
Drug Discovery Today. 28:103518
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08c0746d20a9e843062d8f69f431f337
https://doi.org/10.1016/j.drudis.2023.103518
https://doi.org/10.1016/j.drudis.2023.103518
Publikováno v:
Discover Mental Health. 2
This manuscript reviews the clinical evidence regarding single-dose intravenous (IV) administration of the novel glutamatergic modulator racemic (R,S)-ketamine (hereafter referred to as ketamine) as well as its S-enantiomer, intranasal esketamine, fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba37bbdaf97ed2a0b15ab3c8dfea6d80
https://doi.org/10.1007/s44192-022-00012-3
https://doi.org/10.1007/s44192-022-00012-3
Autor:
Ruin Moaddel, Panos Zanos, Cristan A. Farmer, Bashkim Kadriu, Patrick J. Morris, Jacqueline Lovett, Elia E. Acevedo-Diaz, Grace W. Cavanaugh, Peixiong Yuan, Mani Yavi, Craig J. Thomas, Lawrence T. Park, Luigi Ferrucci, Todd D. Gould, Carlos A. Zarate
Publikováno v:
Translational psychiatry. 12(1)
Subanesthetic-dose racemic (R,S)-ketamine (ketamine) produces rapid, robust, and sustained antidepressant effects in major depressive disorder (MDD) and bipolar disorder (BD) and has also been shown to effectively treat neuropathic pain, complex regi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17bc3b4aaf79ba9c4b6a4e582498302
https://pubmed.ncbi.nlm.nih.gov/35501309
https://pubmed.ncbi.nlm.nih.gov/35501309
Publikováno v:
CNS drugs. 36(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcae694859a193eaca9d019405291b44
https://pubmed.ncbi.nlm.nih.gov/35015265
https://pubmed.ncbi.nlm.nih.gov/35015265
Autor:
Nadia S. Hejazi, Cristan A. Farmer, Mark Oppenheimer, Tolulope B. Falodun, Lawrence T. Park, Wallace C. Duncan, Carlos A. Zarate
Publikováno v:
J Psychiatr Res
The Hamilton Depression Rating Scale (HDRS), which includes several insomnia-related items, is potentially valuable in evaluating both depressive and sleep symptoms. However, the HDRS insomnia items have not been fully assessed by objective measures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e677f0335a037f94863363f7317046
https://pubmed.ncbi.nlm.nih.gov/35092868
https://pubmed.ncbi.nlm.nih.gov/35092868
Autor:
Elizabeth D. Ballard, Cristan A. Farmer, Jessica Gerner, Bartholt Bloomfield-Clagett, Lawrence T. Park, Carlos A. Zarate
Publikováno v:
J Affect Disord
BACKGROUND: Early markers preceding suicide ideation (SI) may provide valuable information for both assessment and treatment. The glutamatergic modulator ketamine has rapid, transient effects on SI, creating an opportunity to observe potential antece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce2f68baba8520b5a61c3dfb517e95a
https://pubmed.ncbi.nlm.nih.gov/35429526
https://pubmed.ncbi.nlm.nih.gov/35429526