Výsledky vyhledávání - "Lawrence Stennett"

Supplementary Table 1 from ON 01910.Na Is Selectively Cytotoxic for Chronic Lymphocytic Leukemia Cells through a Dual Mechanism of Action Involving PI3K/AKT Inhibition and Induction of Oxidative Stress

Autor: Adrian Wiestner, Patricia Pérez-Galán, Diane Arthur, Federica Gibellini, Lawrence Stennett, Mohamed Farooqui, Georg Aue, Mark Roschewski, Xiameng Sun, Colby M. Chapman

PDF file - 71K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98dbaf5a421bda2cd5bc8e0fedd0a18
https://doi.org/10.1158/1078-0432.22443299

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Supplementary Figure 1 from ON 01910.Na Is Selectively Cytotoxic for Chronic Lymphocytic Leukemia Cells through a Dual Mechanism of Action Involving PI3K/AKT Inhibition and Induction of Oxidative Stress

Autor: Adrian Wiestner, Patricia Pérez-Galán, Diane Arthur, Federica Gibellini, Lawrence Stennett, Mohamed Farooqui, Georg Aue, Mark Roschewski, Xiameng Sun, Colby M. Chapman

PDF file - 69K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a9843e2adf29b08857202ee231091b
https://doi.org/10.1158/1078-0432.22443305.v1

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Data from ON 01910.Na Is Selectively Cytotoxic for Chronic Lymphocytic Leukemia Cells through a Dual Mechanism of Action Involving PI3K/AKT Inhibition and Induction of Oxidative Stress

Autor: Adrian Wiestner, Patricia Pérez-Galán, Diane Arthur, Federica Gibellini, Lawrence Stennett, Mohamed Farooqui, Georg Aue, Mark Roschewski, Xiameng Sun, Colby M. Chapman

Purpose: Chronic lymphocytic leukemia (CLL), a malignancy of mature B cells, is incurable with chemotherapy. Signals from the microenvironment support leukemic cell survival and proliferation and may confer chemotherapy resistance. ON 01910.Na (Rigos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e681846ac95553ee79cf1d1c73a9b7
https://doi.org/10.1158/1078-0432.c.6519764

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Supplementary Figure S1 from Proteasome Inhibitors Trigger NOXA-Mediated Apoptosis in Melanoma and Myeloma Cells

Autor: Brian J. Nickoloff, Lucio Miele, Paola Rizzo, Mary J.C. Hendrix, Jeffrey M. Trent, Pamela M. Pollock, Frank Bennett, Vijaya Chaturvedi, Brian K. Bonish, Barbara Bodner, Lawrence Stennett, Jeffrey Ziffra, Jian-Zhong Qin

Supplementary Figure S1 from Proteasome Inhibitors Trigger NOXA-Mediated Apoptosis in Melanoma and Myeloma Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b131fa0666d4f0f323257372b8cc7fcd
https://doi.org/10.1158/0008-5472.22363743

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Supplementary Figure S2 from Proteasome Inhibitors Trigger NOXA-Mediated Apoptosis in Melanoma and Myeloma Cells

Supplementary Figure S2 from Proteasome Inhibitors Trigger NOXA-Mediated Apoptosis in Melanoma and Myeloma Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b1b5d75cb89489016d9b0c313e8540
https://doi.org/10.1158/0008-5472.22363740.v1

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Supplementary Figure S3 from Proteasome Inhibitors Trigger NOXA-Mediated Apoptosis in Melanoma and Myeloma Cells

Supplementary Figure S3 from Proteasome Inhibitors Trigger NOXA-Mediated Apoptosis in Melanoma and Myeloma Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062b051ec793acb2def88c2353f3b70c
https://doi.org/10.1158/0008-5472.22363737

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Data from Proteasome Inhibitors Trigger NOXA-Mediated Apoptosis in Melanoma and Myeloma Cells

Patients with metastatic melanoma or multiple myeloma have a dismal prognosis because these aggressive malignancies resist conventional treatment. A promising new oncologic approach uses molecularly targeted therapeutics that overcomes apoptotic resi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c572f709c2e0bc468cef9171630e8db
https://doi.org/10.1158/0008-5472.c.6493863

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p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas

Autor: Jian-Zhong Qin, Lawrence Stennett, Patricia Bacon, Barbara Bodner, Mary J.C. Hendrix, Richard E.B. Seftor, Elisabeth A. Seftor, Naira V. Margaryan, Pamela M. Pollock, Amy Curtis, Jeffrey M. Trent, Frank Bennett, Lucio Miele, Brian J. Nickoloff

Publikováno v: Molecular Cancer Therapeutics. 3:895-902

Once melanoma metastasizes, no effective treatment modalities prolong survival in most patients. This notorious refractoriness to therapy challenges investigators to identify agents that overcome melanoma resistance to apoptosis. Whereas many surviva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ca9a48b204106a19ba164fc49e63b5e
https://doi.org/10.1158/1535-7163.895.3.8

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