Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Lawrence S. Mathews"'
Autor:
Masayuki Funaba, Lawrence S. Mathews
Publikováno v:
Protein Expression and Purification. 20:507-513
Smads transduce intracellular signals initiated by members of the transforming growth factor beta (TGF beta) family, including activins, TGF betas, and bone morphogenetic proteins. Recently, various models concerning the mechanism of Smad action have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa269641957127e1dface290fa640b08
https://doi.org/10.1006/prep.2000.1315
https://doi.org/10.1006/prep.2000.1315
Publikováno v:
Journal of Biological Chemistry. 273:677-680
The Smad family of intracellular proteins mediates signals generated by activin and other transforming growth factor beta-related proteins via specific heteromeric complexes of transmembrane receptor serine kinases (1, 2). xSmad2 has been implicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127d390f8ac2742a9789dcc69a07fc38
https://doi.org/10.1074/jbc.273.2.677
https://doi.org/10.1074/jbc.273.2.677
Publikováno v:
Development. 124:827-837
Activins and other ligands in the TGFb superfamily signal through a heteromeric complex of receptors. Disruption of signaling by a truncated type II activin receptor, XActRIIB (previously called XAR1), blocks mesoderm induction and promotes neuraliza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a8089b881c897c81445f2c17f967ee
https://doi.org/10.1242/dev.124.4.827
https://doi.org/10.1242/dev.124.4.827
Publikováno v:
Molecular Endocrinology. 10:367-379
Activin is a protein growth and differentiation factor that initiates intracellular events through the activation of a complex of transmembrane protein serine kinases. Two subfamilies of receptor serine kinases, type I and type II, have been identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc165dda0c8f211fea3044d1e887be1
https://doi.org/10.1210/mend.10.4.8721982
https://doi.org/10.1210/mend.10.4.8721982
Autor:
Ronald M. Evans, Wylie Vale, Claudio D. Stern, Kazuhiko Umesono, Akira Kakizuka, Chris Kintner, Ruth T. Yu, Lawrence S. Mathews
Publikováno v:
Developmental Biology. 172:192-205
We have cloned chick homologues of the type-II activin receptor, which we have designated cActR-IIA and -IIB. Binding assays show that the two receptors are indistinguishable in their ability to bind activin-A, with comparablekds. Injection of mRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9a2a1154c126df3c1e2a74f9fdbd3f
https://doi.org/10.1006/dbio.1995.0015
https://doi.org/10.1006/dbio.1995.0015
Publikováno v:
Endocrinology. 134:799-808
We have studied the distribution of activin receptor gene expression in the brain, pituitary, ovary, and testis of the adult rat by in situ hybridization, using probes complementary to the mRNAs encoding the mouse activin receptor subtypes II and IIB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c5de05e6fa8f05c5bc33d7499f2563
https://doi.org/10.1210/endo.134.2.8299574
https://doi.org/10.1210/endo.134.2.8299574
Publikováno v:
Biochemical and Biophysical Research Communications. 191:790-795
A cDNA encoding the rat transforming growth factor-beta (TGF-beta) type II receptor was isolated by hybridization from a rat pituitary gland cDNA library. The rat TGF-beta type II receptor comprises 567 amino acid residues with a cysteine-rich extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8c25fc05c1fddfd80d45ac0d1f360b
https://doi.org/10.1006/bbrc.1993.1286
https://doi.org/10.1006/bbrc.1993.1286
Publikováno v:
Science. 255:1702-1705
A complementary DNA coding for a second type of activin receptor (ActRIIB) has been cloned from Xenopus laevis that fulfills the structural criteria of a transmembrane protein serine kinase. Ectodermal explants from embryos injected with activin rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fa34a2141ecb68245e92b26987d902
https://doi.org/10.1126/science.1313188
https://doi.org/10.1126/science.1313188
Autor:
Joan Vaughan, Alice L. Yu, John Yu, Li-en Shao, Normand L. Frigon, Arlene L. Young, Lawrence S. Mathews, Wylie Vale
Publikováno v:
Blood. 79:773-781
The regulatory control of human erythropoiesis through a purified protein, activin A, was examined. Previous studies using mixed populations of bone marrow cells suggested that activin A has an indirect effect on cellular proliferation and DNA synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a23845906a8e719b44502b98a59558f
https://doi.org/10.1182/blood.v79.3.773.773
https://doi.org/10.1182/blood.v79.3.773.773
Autor:
Lawrence S. Mathews
Publikováno v:
Trends in Endocrinology & Metabolism. 2:176-180
Growth hormone (GH), synthesized in and secreted from the anterior pituitary lobe, has multiple effects at both the cellular and the organismal levels, including promotion of body growth, stimulation of intermediary metabolism, and transcriptional re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb17f492307246d14316da0447be497e
https://doi.org/10.1016/1043-2760(91)90015-f
https://doi.org/10.1016/1043-2760(91)90015-f