Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Lawrence S. Lamb"'
Autor:
Lawrence S. Lamb, Larisa Pereboeva, Samantha Youngblood, G. Yancey Gillespie, L. Burton Nabors, James M. Markert, Anindya Dasgupta, Catherine Langford, H. Trent Spencer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Chemotherapeutic drugs such as the alkylating agent Temozolomide (TMZ), in addition to reducing tumor mass, can also sensitize tumors to immune recognition by transient upregulation of multiple stress induced NKG2D ligands (NKG2DL). However,
Externí odkaz:
https://doaj.org/article/c28e1cc2e93d4747993b3ae118687a18
Autor:
Chia-Wei Chang, Yi-Shin Lai, Erik Westin, Alireza Khodadadi-Jamayran, Kevin M. Pawlik, Lawrence S. Lamb Jr., Frederick D. Goldman, Tim M. Townes
Publikováno v:
Cell Reports, Vol 12, Iss 10, Pp 1668-1677 (2015)
Mutations of the Janus family kinase JAK3 gene cause severe combined immunodeficiency (SCID). JAK3 deficiency in humans is characterized by the absence of circulating T cells and natural killer (NK) cells with normal numbers of poorly functioning B c
Externí odkaz:
https://doaj.org/article/f510a4d63ea34ca2b43e008990411074
Autor:
David F. Bauer, Larisa Pereboeva, G. Yancey Gillespie, Gretchen A. Cloud, Osama Elzafarany, Catherine Langford, James M. Markert, Lawrence S. Lamb Jr.
Publikováno v:
Journal of Immunology Research, Vol 2016 (2016)
We designed multimodal tumor vaccine that consists of irradiated tumor cells infected with the oncolytic IL-12-expressing HSV-1 virus, M002. This vaccine was tested against the syngeneic neuroblastoma mouse model Neuro 2a injected into the right caud
Externí odkaz:
https://doaj.org/article/482a3519db234a9f8b57d03cc14f9f3b
Publikováno v:
Frontiers in Pharmacology, Vol 5 (2014)
Adoptive T-cell therapy can involve donor lymphocyte infusion (DLI) after allogeneic hematopoietic stem cell transplantation, the administration of tumor infiltrating lymphocyte (TILs) expanded ex-vivo, or more recently the use of T cell receptor (TC
Externí odkaz:
https://doaj.org/article/d44bb9725362462d88b6f6d4c8eed308
Autor:
Joseph P. McGuirk, Sunil H Abhyankar, Trishna Goswami, Rupal Soder, Mariska ter Haak, Tyce Bruns, Samantha Langford Youngblood, Lawrence S. Lamb
Publikováno v:
Blood. 140:7464-7465
Autor:
Lawrence S. Lamb, Lei Ding
Publikováno v:
Neuro Oncol
While recent advances in immunotherapies have shown promise in extracranial tumors, Glioblastoma Multiforme (GBM) has remained challenging. We have previously developed a novel approach to the treatment of primary GBM by combining simultaneous intrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2352b2a52bdaa79fabf2239482c64e98
https://europepmc.org/articles/PMC8598488/
https://europepmc.org/articles/PMC8598488/
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundCellular Immunotherapies, which have been transformative in the treatment of liquid tumors, have had extremely limited efficacy in solid tumors to-date, in part due to the challenges of efficiently targeting the tumor heterogeneity. Gamma-d
Autor:
Larisa Pereboeva, Catherine P. Langford, L. Burton Nabors, G. Yancey Gillespie, Anindya Dasgupta, Samantha Youngblood, Lawrence S. Lamb, H. Trent Spencer, James M. Markert
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Scientific Reports
Chemotherapeutic drugs such as the alkylating agent Temozolomide (TMZ), in addition to reducing tumor mass, can also sensitize tumors to immune recognition by transient upregulation of multiple stress induced NKG2D ligands (NKG2DL). However, the pote
Autor:
Ruby F. Meredith, Lawrence S. Lamb, Ayman Saad, Omer Jamy, Donna Salzman, Luciano J. Costa, Kentaro Minagawa, Susan Bal, Raquel Innis-Shelton, Shin Mineishi, Antonio Di Stasi, Ravi Kumar Paluri
Publikováno v:
American Journal of Hematology. 96
Autor:
Lawrence S. Lamb, Hemalatha G. Rangarajan, Ran Reshef, Rodrigo Martino, Mahmoud Aljurf, Parinda A. Mehta, Sachiko Seo, Aleksandr Lazaryan, Hisham Abdel-Azim, Miguel Angel Diaz, Vijaya Raj Bhatt, Jean-Yves Cahn, Olle Ringdén, Robert Peter Gale, Jean A. Yared, Shatha Farhan, Usama Gergis, Daniel R. Couriel, Sagar S. Patel, Peiman Hematti, Betty K. Hamilton, Paul Castillo, Mukta Arora, Bipin N. Savani, Lolie C. Yu, Muna Qayed, Leo F. Verdonck, Abraham S. Kanate, Shahinaz M. Gadalla, David Buchbinder, Manish J. Gandhi, Rammurti T. Kamble, Saurabh Chhabra, Mitchell S. Cairo, Tao Wang, Takanori Teshima, Stephen R. Spellman, Kirk R. Schultz, Hadar A. Frangoul, Vaibhav Agrawal, Taiga Nishihori, Yngvar Fløisand, Amer Beitinjaneh, Michael T. Hemmer, Baldeep Wirk, Pooja Khandelwal, Gerhard C. Hildebrandt, Michael Byrne, Shahrukh K. Hashmi, Ravi Vij, Alvaro Urbano-Ispizua, James Gajewski, Richard F. Olsson, Ayman Saad, Joseph Pidala, Harry C. Schouten, Margaret L. MacMillan, Brian C. Shaffer, Basem M. William, Amin M. Alousi, Edmund K. Waller, David I. Marks, Melhem Solh
Publikováno v:
Biology of Blood and Marrow Transplantation, 25(9), 1875-1883. Elsevier Science
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Data on whether the T cell dose of allogeneic peripheral blood stem cell (PBSC) products influences transplantation outcomes are conflicting. Using the Center for International Blood and Marrow Transplant Research database, we identified 2736 adult p