Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lawrence R. Shiow"'
Autor:
Lucas Schirmer, Wiebke Möbius, Chao Zhao, Andrés Cruz-Herranz, Lucile Ben Haim, Christian Cordano, Lawrence R Shiow, Kevin W Kelley, Boguslawa Sadowski, Garrett Timmons, Anne-Katrin Pröbstel, Jackie N Wright, Jung Hyung Sin, Michael Devereux, Daniel E Morrison, Sandra M Chang, Khalida Sabeur, Ari J Green, Klaus-Armin Nave, Robin JM Franklin, David H Rowitch
Publikováno v:
eLife, Vol 7 (2018)
Glial support is critical for normal axon function and can become dysregulated in white matter (WM) disease. In humans, loss-of-function mutations of KCNJ10, which encodes the inward-rectifying potassium channel KIR4.1, causes seizures and progressiv
Externí odkaz:
https://doaj.org/article/08a072ddc3c447a1bdecec41fc96cfc9
Autor:
Jordan E. Bisanz, Edwina B. Tran, Patrick Barba, Ryan Baumann, Jennifer L. Gommerman, Michael R. Wilson, Lawrence R. Shiow, Jürgen Schlegel, Michael Kutza, Sergio E. Baranzini, Johanna Oechtering, James Landefeld, Jeffrey M. Gelfand, Jennifer Graves, Ryan D. Schubert, Friederike Liesche-Starnecker, Valeria Ramaglia, Lucas Schirmer, Kelsey C. Zorn, Kicheol Kim, Karin Forsberg, Stephen L. Hauser, Xiaoyuan Zhou, Jens Kuhle, Katrin Sellrie, Roland G. Henry, Khashayar Khaleghi, Akshaya Ramesh, Stephanie Vistnes, Bruce A.C. Cree, Peter M. Andersen, Peter J. Turnbaugh, Gina Kirkish, Peter H. Seeberger, Sven Wischnewski, Olga L. Rojas, Ariele L. Greenfield, Anne-Katrin Pröbstel, Ravi Dandekar, Sneha Singh, Antje Bischof
Publikováno v:
Science Immunology. 5
Changes in gut microbiota composition and a diverse role of B cells have recently been implicated in multiple sclerosis (MS), a central nervous system (CNS) autoimmune disease. Immunoglobulin A (IgA) is a key regulator at the mucosal interface. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::800a2771ca9f520b72d86f2e52d86f5b
https://doi.org/10.1126/sciimmunol.abc7191
https://doi.org/10.1126/sciimmunol.abc7191
Autor:
Maike Steindel, Dorothy P. Schafer, Omer Ali Bayraktar, Jan Broder Engler, Dmitry Velmeshev, Lawrence R. Shiow, Aparna Bhaduri, Richard Reynolds, David H. Rowitch, John H. Stockley, Maximilian Haeussler, Max Kaufmann, Brian Tung, Nitasha Goyal, Stephanie Vistnes, Arnold R. Kriegstein, Robin J.M. Franklin, Diane Jung, Manuel A. Friese, Simone Mayer, Sebastian Werneburg, Staffan Holmqvist, Lucas Schirmer, Adam Young
Publikováno v:
Nature, vol 573, iss 7772
Nature
Nature
Multiple sclerosis (MS) is a neuroinflammatory disease with a relapsing-remitting disease course at early stages, distinct lesion characteristics in cortical grey versus subcortical white matter and neurodegeneration at chronic stages. Here we used s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340b3c64f631133e1768fea137d0d953
https://escholarship.org/uc/item/3zw1916g
https://escholarship.org/uc/item/3zw1916g
Autor:
Khalida Sabeur, Chao Zhao, Jackie N Wright, Christian Cordano, David H. Rowitch, Garrett Timmons, Ari J. Green, Kevin W. Kelley, Boguslawa Sadowski, Lawrence R. Shiow, Jung Hyung Sin, Robin J.M. Franklin, Lucas Schirmer, Wiebke Möbius, Lucile Ben Haim, Michael Devereux, Andrés Cruz-Herranz, Klaus-Armin Nave, Daniel E Morrison, Sandra Chang, Anne-Katrin Pröbstel
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Glial support is critical for normal axon function and can become dysregulated in white matter (WM) disease. In humans, loss-of-function mutations of KCNJ10, which encodes the inward-rectifying potassium channel KIR4.1, causes seizures and progressiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57aaf153571d1777f432d67bf0c4fe1e
Autor:
Michael Devereux, Garrett Timmons, Kevin W. Kelley, Andrés Cruz-Herranz, Jackie N Wright, Boguslawa Sadowski, Christian Cordano, Wiebke Möbius, Lucas Schirmer, Ari J. Green, Robin J.M. Franklin, Jung Hyung Sin, Khalida Sabeur, Klaus-Armin Nave, Lucile Ben Haim, Lawrence R. Shiow, David H. Rowitch, Daniel E Morrison, Sandra Chang, Anne-Katrin Pröbstel, Chao Zhao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00905c368f965ce6afbb2d38eb6c3033
https://doi.org/10.7554/elife.36428.020
https://doi.org/10.7554/elife.36428.020
Autor:
Hiroko Nobuta, Bobbi Fleiss, Christian R. Andres, Géraldine Favrais, Lucas Schirmer, Pierre Gressens, David H. Rowitch, Lawrence R. Shiow, Anne Laure Schang, Sara Cipriani, Jackie N Wright
Inflammation is a major risk factor for neonatal white matter injury (NWMI), which is associated with later development of cerebral palsy. Although recent studies have demonstrated maturation arrest of oligodendrocyte progenitor cells (OPCs) in NWMI,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da41c3bfc3af099b757cef0afdb7005e
https://europepmc.org/articles/PMC5753598/
https://europepmc.org/articles/PMC5753598/
Autor:
Eric J. Huang, David H. Rowitch, John C. Silbereis, Lawrence R. Shiow, Tracy J. Yuen, Stavros Lomvardas, Stephen P.J. Fancy, Sergio E. Baranzini, Emily P. Harrington
Publikováno v:
Nature neuroscience
Nature neuroscience, vol 17, iss 4
Nature neuroscience, vol 17, iss 4
In colon cancer, mutation of the Wnt repressor APC (encoding adenomatous polyposis coli) leads to a state of aberrant and unrestricted high-activity signaling. However, the relevance of high Wnt tone in non-genetic human disease is unknown. Here we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9904bce61b52fff25547603025ec0f64
http://europepmc.org/articles/PMC3975168
http://europepmc.org/articles/PMC3975168
Autor:
David W. Roadcap, Ricardo U. Sorensen, Christopher C. Goodnow, Jason G. Cyster, Tonya Lebet, Susan R. Watson, Craig N. Jenne, Jennifer M. Puck, Ying Xu, Lawrence R. Shiow, James E. Bear, Kenneth Paris, Irina L. Grigorova, Jinping An, Niko Föger
Publikováno v:
Nature immunology, vol 9, iss 11
Mice carrying the recessive locus for peripheral T cell deficiency (Ptcd) have a block in thymic egress, but the mechanism responsible is undefined. Here we found that Ptcd T cells had an intrinsic migration defect, impaired lymphoid tissue trafficki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2963b97969eb97437027c9e3e073f566
https://doi.org/10.1038/ni.1662
https://doi.org/10.1038/ni.1662
Autor:
Lorenzo Berti, Jennifer Tom, George F. Sensabaugh, Igor L. Medintz, Wendy W. Wong, James R. Scherer, Richard A. Mathies, Lawrence R. Shiow
Publikováno v:
Genome Research. 11:413-421
An assay is described for high-throughput single nucleotide polymorphism (SNP) genotyping on a microfabricated capillary array electrophoresis (CAE) microchip. The assay targets the three common variants at the HFE locus associated with the genetic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75aaa49437f68f99767acccbbc8de1b
https://doi.org/10.1101/gr.164701
https://doi.org/10.1101/gr.164701
Publikováno v:
Primary Immunodeficiency Diseases: A Molecular and Genetic Approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1375a81d0454a1ea977fcf112cd87509
https://doi.org/10.1093/med/9780195389838.003.0023
https://doi.org/10.1093/med/9780195389838.003.0023