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pro vyhledávání: '"Lawrence R. Freedman"'
Autor:
Lawrence R. Freedman
The most important example of intravascular infection is infective endocarditis (IE), a common and serious disorder in man. In the past, these infections were uniformly fatal, but since the development of potent antimicrobial agents, bac teriologic
Autor:
Alan L. Bisno, Donald Kaye, David N. Gilbert, Walter R. Wilson, Craig R. Smith, George L. Drusano, Lawrence R. Freedman
Publikováno v:
Clinical Infectious Diseases. 15:S89-S95
These guidelines describe the design and implementation of clinical trials to assess the safety and efficacy of anti-infective drugs for the treatment of infective endocarditis. Identification and enrollment of patients in clinical trials is based on
Autor:
Lawrence R. Freedman
Publikováno v:
The Journal of Infectious Diseases. 179:S291-S293
I was deeply honored to be invited to speak of the history of this esteemed society. As I reflected upon it, the subject that at first seemed simple took on a deeper and more complex meaning. An important quest for me, in giving a talk about any subj
Autor:
Lawrence R. Freedman
Publikováno v:
Clinical Infectious Diseases. 17:195-197
Autor:
Andrew D. Lipman, Lawrence R. Freedman
Publikováno v:
Alternatives to the High Cost of Litigation. 14:123-124
Autor:
Lawrence R. Freedman
Publikováno v:
New England Journal of Medicine. 328:143-144
Autor:
Lawrence R. Freedman
Publikováno v:
Annals of Internal Medicine. 126:921
Autor:
Lawrence R. Freedman
Publikováno v:
The Sciences. 22:22-25
HIROSHIMA AND NAGASAKI: The Physical, Medical, and Social Effects of the Atomic Bombings Edited by the Committee for the Compilation of Materials on Damage Caused by the Atomic Bombs in Hiroshima and Nagasaki
Autor:
Lawrence R. Freedman
Publikováno v:
Journal of Antimicrobial Chemotherapy. 20:1-6
Three aspects of our current understanding of the pathogenesis of infective endocarditis are reviewed: the size of the infected vegetation, host defence mechanisms and conditions which determine the outcome of experimental infection. Animal studies h
Autor:
James Valone, Lawrence R. Freedman
Publikováno v:
Progress in Cardiovascular Diseases. 22:169-180
I T WAS about 100 yr ago that bacteria were identified as the cause of infective endocarditis. Subsequently, there was a long period of clinical observation, during which time the natural history and secondary manifestations of the disease were defin