Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lawrence M. Zaccaro"'
Autor:
Lee A. Morehouse, Faan-Wen Bangerter, Michael P. DeNinno, Philip B. Inskeep, Peter A. McCarthy, Judith L. Pettini, Yvette E. Savoy, Eliot D. Sugarman, Robert W. Wilkins, Theresa C. Wilson, Heidi A. Woody, Lawrence M. Zaccaro, Charles E. Chandler
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 3, Pp 464-474 (1999)
The hypocholesterolemic activities of pamaqueside and tiqueside, two structurally similar saponins, were evaluated in cholesterol-fed rabbits. The pharmacological profiles of the saponins were virtually identical: both dose-dependently decreased the
Externí odkaz:
https://doaj.org/article/54949688d31149199b023ce42391549f
Autor:
Lawrence M. Zaccaro, Theresa C. Wilson, Mccarthy Peter A, Faan-Wen Bangerter, Charles E. Chandler, Michael P. DeNinno, R.W. Wilkins, Heidi A. Woody, Lee A. Morehouse, Judith L. Pettini, Yvette E. Savoy, Philip B. Inskeep, Eliot Sugarman
Publikováno v:
Journal of Lipid Research. 40:464-474
The hypocholesterolemic activities of pamaqueside and tiqueside, two structurally similar saponins, were evaluated in cholesterol-fed rabbits. The pharmacological profiles of the saponins were virtually identical: both dose-dependently decreased the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b43d4f032357a817090b9979fccd35df
https://doi.org/10.1016/s0022-2275(20)32451-2
https://doi.org/10.1016/s0022-2275(20)32451-2
Autor:
Charles E. Chandler, Michael P. Zawistoski, R.W. Wilkins, Heidi A. Woody, Michael P. DeNinno, Eliot Sugarman, John B. Etienne, Cynthia Eller, Kimberly C. Duplantier, Mccarthy Peter A, Lawrence M. Zaccaro, F.W. Bangerter, Lee A. Morehouse
Publikováno v:
Journal of Medicinal Chemistry. 40:2547-2554
We have explored the use of steroidal glycosides as cholesterol absorption inhibitors which act through an unknown mechanism. The lead for this program was tigogenin cellobioside (1, tiqueside) which is a weak inhibitor (ED50 = 60 mg/kg) as measured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8bf6347bb2d2ceba68223277c4f5158
https://doi.org/10.1021/jm9702600
https://doi.org/10.1021/jm9702600
Autor:
John P. O'Donnell, Walinsky Stanley W, R.W. Wilkins, Mccarthy Peter A, Michael P. Zawistoski, Kimberly C. Duplantier, Lee A. Morehouse, Charles E. Chandler, Theresa C. Wilson, F.W. Bangerter, Susan L. Pezzullo, John B. Etienne, Lambert John F, Watson Harry A, Frank J. Urban, Michael P. DeNinno, Patricia G. Cosgrove, Michael A. Fowler, Lawrence M. Zaccaro
Publikováno v:
Journal of Medicinal Chemistry. 39:1935-1937
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67dc0168fe43f33e1c1cc90dfabd323
https://doi.org/10.1021/jm960123n
https://doi.org/10.1021/jm960123n
Autor:
William H. Martin, Victor F. Soliman, Lawrence M. Zaccaro, Lorraine D. Shelly, Diane M. Hargrove, Stephen F. Petras, H. James Harwood, Deepak Dalvie, Mularski Christian J, W. Ross Tracey, Michael Raymond Makowski, William P. Magee, Justin Chapman, Kelly A. Martin, Shane A. Eisenbeis, David Austen Perry
Publikováno v:
The Journal of biological chemistry. 278(39)
Inhibition of acetyl-CoA carboxylase (ACC), with its resultant inhibition of fatty acid synthesis and stimulation of fatty acid oxidation, has the potential to favorably affect the multitude of cardiovascular risk factors associated with the metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb98042320064c52c59d1309eac8aab
https://pubmed.ncbi.nlm.nih.gov/12842871
https://pubmed.ncbi.nlm.nih.gov/12842871
Publikováno v:
Alcohol (Fayetteville, N.Y.). 5(3)
Fluorescent probes were used to compare the physical properties of membranes from mice selected for sensitivity (LS) and insensitivity (SS) to the hypnotic action of ethanol. Brain synaptic plasma membranes (SPM) from LS mice were more sensitive to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef1074a9727f976034133e9a418af93
https://pubmed.ncbi.nlm.nih.gov/3415769
https://pubmed.ncbi.nlm.nih.gov/3415769