Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Lawrence Kilham"'
Autor:
Clare Wilcox, Maxwell Finland, Manson Meads, Roderick Murray, Lawrence Kilham, H. William Harris
Publikováno v:
Journal of the American Medical Association. 132
The early laboratory and clinical experiences with streptomycin have already indicated that the problem of acquired resistance may be of considerably greater importance with this agent than with the sulfonamides or with penicillin. 1 The rapid develo
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 63(2)
ConclusionsIt was possible to increase the resistance of Gram-negative bacilli to over 50,000 units per ml, in all cases studied, by passage through increasing concentrations of streptomycin in bro...
Autor:
Lawrence Kilham, George Margolis
Publikováno v:
Teratology. 13:179-184
Pregnant and lactating hamsters were inoculated with reovirus type 3 and H-1 virus to determine whether they had any special susceptibility as compared with nonpregnant controls; whole blood, liver, and uterus were tested for virus on successive days
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 33:13-28
Recent studies by Johnson and Johnson have provided new insights into encephalitis complicating mumps and the pathogenicity of mumps virus for the developing brain. Upon inoculation into suckling hamsters mumps virus induces a destructive ependymitis
Autor:
George Margolis, Lawrence Kilham
Publikováno v:
Experimental and Molecular Pathology. 27:235-248
We describe induction of obstructive hydrocephalus by intra-amniotic inoculation of parainfluenza type 2 virus into 10- to 12-day pregnant hamsters. As determined by cytoplasmic inclusions, specific immunofluorescence, cytopathic effects, inflammatio
Autor:
George Margolis, Lawrence Kilham
Publikováno v:
Experimental and Molecular Pathology. 29:44-54
This report describes a spectrum of cytotoxic and teratogenic effects induced in late stage fetal and early suckling hamsters and rats with the antiviral drug Ribavirin. The adverse effects include granuloprival cerebellar hypoplasia, epidermal defec
Autor:
Paul N. Baer, Lawrence Kilham
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology. 37:385-389
Cementomas and odontomas were found in the jaws of 18-month-old hamsters which had been infected with minute virus of mice (MVM) at 5 days of age.
Publikováno v:
Experimental and Molecular Pathology. 23:228-244
This report describes the investigation of the pathogenesis of an unusual sequel of reovirus encephalitis in suckling rats. Intracerebral inoculation of reovirus types 1, 2, and 3 into suckling rats induced, in addition to viral cytoplasmic inclusion
Publikováno v:
Teratology. 17:93-101
Ribavirin, a synthetic nucleoside with marked antiviral activity, induced developmental malformations when administered to pregnant hamsters by oral, intraperitoneal or intravenous routes. Abnormalities of the limbs, eyes and brain were the most comm
Autor:
Lawrence Kilham
Publikováno v:
The Auk. 90:597-609