Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Lawrence K. Low"'
Autor:
Lawrence K. Low, Joo Y. Song
Publikováno v:
Surgical Pathology Clinics. 9:55-77
The diagnosis of lymphoproliferative disorders associated with immunodeficiency can be challenging because many of these conditions have overlapping clinical and pathologic features and share similarities with their counterparts in the immunocompeten
Publikováno v:
Developmental Neuroscience. 29:6-13
During early development of the central nervous system (CNS), there is an exuberant outgrowth of projections which later need to be refined to achieve precise connectivity. One widely used strategy for this refinement is axon pruning. Axon pruning ha
Autor:
Hwai-Jong Cheng, Lawrence K. Low
Publikováno v:
Current Opinion in Neurobiology. 15:549-556
While building the nervous system, regions of some developing axons are eliminated; this can also happen as a result of axonal injury. During development, many axon branches that are formed in excess of an organism's needs are fated for removal in a
Publikováno v:
Journal of the American College of Toxicology. 14:40-60
In vitro studies were carried out to investigate whether target organ susceptibility to benzene-induced solid tumor formation is governed by tissue-specific differences in metabolism. The ability of several target and nontarget tissues to deconjugate
Autor:
Jeffrey Coble, Lawrence K. Low, Hwai-Jong Cheng, Regina L. Faulkner, Xiao-Bo Liu, Edward G. Jones
Publikováno v:
Neural Development, Vol 3, Iss 1, p 21 (2008)
Neural Development
Neural development, vol 3, iss 1
Neural Development
Neural development, vol 3, iss 1
Background The development of the corticospinal tract (CST) in higher vertebrates relies on a series of axon guidance decisions along its long projection pathway. Several guidance molecules are known to be involved at various decision points to regul
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(23)
Neurons in the developing CNS tend to send out long axon collaterals to multiple target areas. For these neurons to attain specific connections, some of their axon collaterals are subsequently pruned—a process called stereotyped axon pruning. One o
Autor:
Mike I. H. Comber, David W. Roberts, Ovanes G. Mekenyan, Petra S. Kern, Grace Patlewicz, Charlotte Bernhard Madsen, Lawrence K. Low, Jay Russell Niemelä, S. Dimitrov, Gergana Dimitrova, Paul T. Bailey, Eva Bay Wedebye, Richard D. Phillips, Aynur O. Aptula
Publikováno v:
Technical University of Denmark Orbit
The TImes MEtabolism Simulator platform used for predicting skin sensitization (TIMES-SS) is a hybrid expert system that was developed at Bourgas University using funding and data from a consortium comprised of industry and regulators. TIMES-SS encod
Autor:
Thomas F. Parkerton, Mike I. H. Comber, Todor Pavlov, O. Mekenyan, R Bias, P Reuschenbach, S. Dimitrov, Lawrence K. Low, C Lee, M Silvani, D Nedelcheva
Publikováno v:
SAR and QSAR in environmental research. 18(5-6)
Biodegradation plays a key role in the environmental risk assessment of organic chemicals. The need to assess biodegradability of a chemical for regulatory purposes supports the development of a model for predicting the extent of biodegradation at di
Autor:
Ovanes G. Mekenyan, Grace Patlewicz, Paul T. Bailey, Charlotte Bernhard Madsen, David W. Roberts, Eva Bay Wedebye, Petra S. Kern, Lawrence K. Low, S. Dimitrov, Jay Russell Niemelä, Mike I. H. Comber, Gergana Dimitrova, Aynur O. Aptula, Richard D. Phillips
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 48(2)
The TImes MEtabolism Simulator platform used for predicting Skin Sensitization (TIMES-SS) is a hybrid expert system that was developed at Bourgas University using funding and data from a Consortium comprising industry and regulators. The model was de
Autor:
Hwai-Jong Cheng, Lawrence K. Low
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 361(1473)
Regressive events play a key role in modifying neural connectivity in early development. An important regressive event is the pruning of neuronal processes. Pruning is a strategy often used to selectively remove exuberant neuronal branches and connec