Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Lawrence K. Lee"'
Publikováno v:
Small Structures, Vol 5, Iss 4, Pp n/a-n/a (2024)
Deoxyribonucleic acid (DNA) origami enables the synthesis of bespoke nanoscale structures suitable for diverse applications. Effective design requires preventing uncontrolled aggregation, while still facilitating directed multi‐subunit assembly. Un
Externí odkaz:
https://doaj.org/article/b36b6c4e9c22475da8ac1d2f53c55fde
Autor:
Sophie Hertel, Richard E Spinney, Stephanie Y Xu, Thomas E Ouldridge, Richard G Morris, Lawrence K Lee
Publikováno v:
Nucleic Acids Research. 50:7829-7841
The kinetics of DNA hybridization are fundamental to biological processes and DNA-based technologies. However, the precise physical mechanisms that determine why different DNA sequences hybridize at different rates are not well understood. Secondary
Autor:
James W. P. Brown, Rokiah G. Alford, James C. Walsh, Richard E. Spinney, Stephanie Y. Xu, Sophie Hertel, Jonathan F. Berengut, Lisanne M. Spenkelink, Antoine M. van Oijen, Till Böcking, Richard G. Morris, Lawrence K. Lee
Publikováno v:
ACS nano. 16(4)
Biomolecular complexes can form stable assemblies yet can also rapidly exchange their subunits to adapt to environmental changes. Simultaneously allowing for both stability and rapid exchange expands the functional capacity of biomolecular machines a
Autor:
Sophie Hertel, Richard E. Spinney, Stephanie Y. Xu, Thomas E. Ouldridge, Richard G. Morris, Lawrence K. Lee
The kinetics of DNA hybridisation are fundamental to biological processes and DNA-based technologies. However, the precise physical mechanisms that determine why different DNA sequences hybridise at different rates are not well understood. Secondary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a37f5fba40e873f43b13da03d98ffd1
https://doi.org/10.1101/2021.12.17.473246
https://doi.org/10.1101/2021.12.17.473246
Autor:
Katharina Gaus, Daniel J. Nieves, Geva Hilzenrat, Lawrence K. Lee, Matthew A. B. Baker, Jonathan F. Berengut
Publikováno v:
Nanoscale. 11:12460-12464
Quantitative PAINT (qPAINT) is a useful method for counting well-separated molecules within nanoscale assemblies. But whether cross-reactivity in densely-packed arrangements perturbs measurements is unknown. Here we establish that qPAINT measurements
Autor:
Thomas E. Ouldridge, Jonathan F. Berengut, Chak Kui Wong, Julian C. Berengut, Jonathan P. K. Doye, Lawrence K. Lee
Publikováno v:
ACS nano. 14(12)
Biology demonstrates how a near infinite array of complex systems and structures at many scales can originate from the self-assembly of component parts on the nanoscale. But to fully exploit the benefits of self-assembly for nanotechnology, a crucial
Autor:
Lawrence K. Lee, Jonathan F. Berengut, Jonathan P. K. Doye, Domen Prešern, Julian C. Berengut, Akihiro Kawamoto, Madeleine J Wainwright, Juanfang Ruan
Publikováno v:
Nucleic Acids Research
DNA origami allows for the synthesis of nanoscale structures and machines with nanometre precision and high yields. Tubular DNA origami nanostructures are particularly useful because their geometry facilitates a variety of applications including nano
Autor:
Jonathan F. Berengut, Lawrence K. Lee, Daniel J. Nieves, Geva Hilzenrat, Matthew A. B. Baker, Katharina Gaus
Quantitative PAINT (qPAINT) is a useful method for counting well-separated molecules within nanoscale assemblies. But whether cross-reactivity in densely-packed arrangements perturbs measurements is unknown. Here we establish that qPAINT measurements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7e20706214561329847632b049253b
Autor:
Anthony P. Duff, Robert M.G. Hynson, Lorraine A Ganuelas, Adelle C.F. Coster, Alastair G. Stewart, Lawrence K. Lee, Matthew A. B. Baker, Eleni Giannoulatou, Katharina Gaus, Joshua W. K. Ho, Walid Al-Zyoud, Till Böcking, Dali Liu
Publikováno v:
Nucleic Acids Research
Mechanisms for transcription factor recognition of specific DNA base sequences are well characterized and recent studies demonstrate that the shape of these cognate binding sites is also important. Here, we uncover a new mechanism where the transcrip
Autor:
Katherine E. Dunn, Andrew E. Whitten, Andrew J. Turberfield, Robert M.G. Hynson, Matthew A. B. Baker, Anthony P. Duff, Jonathan Bath, Florence Benn, Lawrence K. Lee, Andrew Tuckwell, Jonathan F. Berengut
Publikováno v:
Baker, M A B, Tuckwell, A J, Berengut, J F, Bath, J, Benn, F, Duff, A P, Whitten, A E, Dunn, K E, Hynson, R M, Turberfield, A J & Lee, L K 2018, ' Dimensions and Global Twist of Single-Layer DNA Origami Measured by Small-Angle X-ray Scattering ', ACS Nano, vol. 12, no. 6, pp. 5791-5799 . https://doi.org/10.1021/acsnano.8b01669
ACS Nano
ACS Nano
The rational design of complementary DNA sequences can be used to create nanostructures that self-assemble with nanometer precision. DNA nanostructures have been imaged by atomic force microscopy and electron microscopy. Small-angle X-ray scattering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1160ca7a8685ecb0799a23f4b7305be1
https://www.pure.ed.ac.uk/ws/files/74660333/Baker_and_Tuckwell_et_al_ACS_Nano_Main_Text_and_Figures_revised.pdf
https://www.pure.ed.ac.uk/ws/files/74660333/Baker_and_Tuckwell_et_al_ACS_Nano_Main_Text_and_Figures_revised.pdf