Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Lawrence J. Mulligan"'
Autor:
Lawrence J. Mulligan, Julian Thrash, Ludmil Mitrev, Douglas Folk, Alyssa Exarchakis, Daniel Ewert, Jeffrey C. Hill
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
IntroductionThis study evaluated the hypothesis that vascular aging (VA) reduces ventricular contractile function and mechanical efficiency (ME) using the left ventricular pressure-volume (PV) construct.MethodsA previously published in-silico computa
Externí odkaz:
https://doaj.org/article/d334352faaca4cee8c98450c95fd1b07
Autor:
Lawrence J. Mulligan, Justin Ungerleider, Adam Friedman, Benjamin Sanders, Julian Thrash, Daniel Ewert, Ludmil Mitrev, Jeffrey C. Hill
Publikováno v:
Physiological Reports, Vol 12, Iss 3, Pp n/a-n/a (2024)
Abstract Mean arterial pressure and cardiac output provide insufficient guidance for the management of intraoperative hypotension (IOH). In silico models offer additional insights into acute changes in hemodynamic parameters that may be encountered d
Externí odkaz:
https://doaj.org/article/54ff743c87a443c38ad814d86ddc609c
Publikováno v:
Journal of Cardiac Failure. 29:568-569
Autor:
Imad Ahmado, Lawrence J. Mulligan, Jagdesh Kandala, Gaurav A. Upadhyay, Jagmeet P. Singh, Lindsay Riedl, Abhishek Bose, Henry Gewirtz, Ram Padmanabhan
Publikováno v:
Journal of Cardiovascular Electrophysiology. 25:507-513
Role of Ischemia and Scar in CRT Patients with CAD Introduction Cardiac resynchronization therapy (CRT) recipients with ischemic cardiomyopathy (ICM) have scar segments that may limit ventricular resynchronization and clinical response. The impact of
Autor:
Kiran Patel, Tarek Haddad, Russell E A Smith, Robin J. Taylor, Paul W X Foley, Fraz Umar, Berthold Stegemann, Lawrence J. Mulligan, Sanjay K Prasad, Francisco Leyva
Publikováno v:
Journal of the American College of Cardiology. 60:1659-1667
ObjectivesThe aim of this study was to determine whether left ventricular (LV) midwall fibrosis, detected by midwall hyperenhancement (MWHE) on late gadolinium enhancement cardiovascular magnetic resonance (CMR) imaging, predicts mortality and morbid
Autor:
Jeffrey H. Omens, Roy C. P. Kerckhoffs, James W. Covell, Lawrence J. Mulligan, Elliot J. Howard, Andrew D. McCulloch
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 301:H1447-H1455
Recently, attention has been focused on comparing left ventricular (LV) endocardial (ENDO) with epicardial (EPI) pacing for cardiac resynchronization therapy. However, the effects of ENDO and EPI lead placement at multiple sites have not been studied
Autor:
Jeremy N. Ruskin, Faisal M. Merchant, Lawrence J. Mulligan, Michael H. Picard, Mary Orencole, E. Kevin Heist, Lindsay Riedl, David McCarty, Jagmeet P. Singh, Dan Blendea, K. Veena Nandigam
Publikováno v:
Pacing and Clinical Electrophysiology. 33:575-582
Background: Both anatomic interlead separation and left ventricle lead electrical delay (LVLED) have been associated with outcomes following cardiac resynchronization therapy (CRT). However, the relationship between interlead distance and electrical
Autor:
Roy C. P. Kerckhoffs, Lawrence J. Mulligan, Elliot J. Howard, Stuart G. Campbell, Jazmin Aguado-Sierra, Jeffrey H. Omens, Benjamin A. Coppola, Andrew D. McCulloch
Publikováno v:
Experimental Physiology. 94:541-552
The excitation-contraction coupling properties of cardiac myocytes isolated from different regions of the mammalian left ventricular wall have been shown to vary considerably, with uncertain effects on ventricular function. We embedded a cell-level e
Publikováno v:
Medical Image Analysis. 13:362-369
To study the impact of biventricular pacing (BiV) and scar size on left ventricular (LV) regional and global function using a detailed finite element model of three-dimensional electromechanics in the failing canine heart.Cardiac resynchronization th
Autor:
Roy C. P. Kerckhoffs, Lawrence J. Mulligan, Jeffrey H. Omens, Sanjiv M. Narayan, Andrew D. McCulloch
Publikováno v:
Heart Failure Clinics. 4:371-378
Advances in computer power, novel diagnostic and therapeutic medical technologies, and an increasing knowledge of pathophysiology from gene to organ systems make it increasingly feasible to apply multiscale patient-specific modeling based on proven d