Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Lawrence J. Fischer"'
Publikováno v:
Molecular Nutrition & Food Research. 50:934-944
The cancer bioassay for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) conducted by the Dow Chemical company in the mid 70s has been used extensively for conducting quantitative cancer risk assessments for human exposure to TCDD. More recently the Nation
Publikováno v:
Environmental Health Perspectives
High levels of maternal fish consumption during pregnancy have been associated with longer gestation (Borod et al. 1999; Olsen and Secher 1990, 2002; Olsen et al. 1989, 1991, 1992, 2000; Reddy et al. 1994), increased birth weight (Borod et al. 1999;
Autor:
Thomas F.X. Collins, Ronald H. Gray, R. Woodrow Setzer, Ulrike Luderer, Kimberley A. Treinen, George P. Daston, Andrew F. Olshan, Roel Vermeulen, Franklin E. Mirer, Lawrence J. Fischer
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 77:110-193
Autor:
Jeanne Manson, Michael J. Brabec, Judy Buelke-Sam, Gary P. Carlson, Robert E. Chapin, John B. Favor, Lawrence J. Fischer, Dale Hattis, Peter S.J. Lees, Sally Perreault-Darney, Joe Rutledge, Thomas J. Smith, Raymond R. Tice, Peter Working
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 74:17-113
Jeanne Manson, Michael J. Brabec, Judy Buelke-Sam, Gary P. Carlson, Robert E. Chapin, John B. Favor, Lawrence J. Fischer, Dale Hattis, Peter S.J. Lees, Sally Perreault-Darney, Joe Rutledge, Thomas J. Smith, Raymond R. Tice and Peter Working Universit
Publikováno v:
Toxicological Sciences. 79:258-265
The antihistaminic, antiserotonergic drug cyproheptadine (CPH) is known to inhibit insulin synthesis in vivo and in vitro. This inhibition of insulin synthesis occurs without a commensurate decrease in preproinsulin mRNA (PPImRNA) levels, suggesting
Autor:
Lawrence J. Fischer, Margaret A. Wagner, John F. Quensen, Stephen Boyd, Mahmoud A. Mousa, Patricia E. Ganey
Publikováno v:
Environmental Toxicology and Chemistry. 19:1311-1316
Bioremediation of polychlorinated hiphenyls (PCBs) by anaerobic microhial dechlorination occurring naturally in the subsurface and in engineered systems results in mixtures of lower-chlorinated, primarily ortho-substituted biphenyls. The purpose of t
Publikováno v:
Toxicology and Applied Pharmacology. 159:194-203
Polychlorinated biphenyls (PCBs) are environmental contaminants that induce release of insulin in rat insulinoma cells, RINm5F (Fischer et al., Life Sci. (1996) 59, 2041–2049). In the present study the mechanisms of this effect were investigated us
Autor:
Michael A. Kamrin, Lawrence J. Fischer
Publikováno v:
Regulatory Toxicology and Pharmacology. 29:175-181
During the past two decades, there have been a number of efforts to harmonize the advice given by different jurisdictions to consumers of sport-caught fish from the Great Lakes. Five years ago, an eight-state task force arrived at consensus recommend
Autor:
Prasada Rao S. Kodavanti, Patricia E. Ganey, Isaac N. Pessah, Richard F. Seegal, Lawrence J. Fischer
Publikováno v:
Toxicological Sciences. 41:49-61
Research into the mechanism of toxicity of PCBs has focused on the Ah receptor. However, it is becoming increasingly clear that certain ortho-chlorine-substituted, non-coplanar PCB congeners having low affinity for the Ah receptor exhibit important b
Autor:
B V Madhukar, Mahmoud A. Mousa, John P. Giesy, Stephen Boyd, J F Quensen rd, Patricia E. Ganey, Karen Chou, Lawrence J. Fischer
Publikováno v:
Environmental Health Perspectives
The reductive dechlorination of polychlorinated biphenyls (PCBs) by anaerobic bacteria has recently been established as an important environmental fate of these compounds. This process removes chlorines directly from the biphenyl ring with replacemen