Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lawrence Humphreys"'
Autor:
José David Celdrán, Lawrence Humphreys, Desirée González, Cristina Soto-Sánchez, Gema Martínez-Navarrete, Iván Maldonado, Idoia Gallego, Ilia Villate-Beitia, Myriam Sainz-Ramos, Gustavo Puras, José Luis Pedraz, Eduardo Fernández
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1860 (2023)
Gene therapy and optogenetics are becoming promising tools for treating several nervous system pathologies. Currently, most of these approaches use viral vectors to transport the genetic material inside the cells, but viruses present some potential r
Externí odkaz:
https://doaj.org/article/5e6b8f583616410d9d5f3e0d80d488ce
Autor:
Miguel Sanchez-Martos, Gema Martinez-Navarrete, Adela Bernabeu-Zornoza, Lawrence Humphreys, Eduardo Fernandez
Publikováno v:
Nanomaterials, Vol 11, Iss 7, p 1756 (2021)
Cationic polypeptides and cationic polymers have cell-penetrating capacities and have been used in gene transfer studies. In this study, we investigate the capability of a polymer of d-lysine (PDL), a chiral form of α–Poly-lysine, as a possible no
Externí odkaz:
https://doaj.org/article/18601a124ac0413e84e0a8174e34835a
Autor:
Fernández, José David Celdrán, Lawrence Humphreys, Desirée González, Cristina Soto-Sánchez, Gema Martínez-Navarrete, Iván Maldonado, Idoia Gallego, Ilia Villate-Beitia, Myriam Sainz-Ramos, Gustavo Puras, José Luis Pedraz, Eduardo
Publikováno v:
Pharmaceutics; Volume 15; Issue 7; Pages: 1860
Gene therapy and optogenetics are becoming promising tools for treating several nervous system pathologies. Currently, most of these approaches use viral vectors to transport the genetic material inside the cells, but viruses present some potential r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::fa8ea398f778fdce5c9eedcab475b4ab
Autor:
Gema Martínez-Navarrete, Eduardo Fernández, Miguel Sanchez-Martos, Adela Bernabeu-Zornoza, Lawrence Humphreys
Publikováno v:
Nanomaterials
Volume 11
Issue 7
Nanomaterials, Vol 11, Iss 1756, p 1756 (2021)
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname
Volume 11
Issue 7
Nanomaterials, Vol 11, Iss 1756, p 1756 (2021)
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname
Cationic polypeptides and cationic polymers have cell-penetrating capacities and have been used in gene transfer studies. In this study, we investigate the capability of a polymer of d-lysine (PDL), a chiral form of α–Poly-lysine, as a possible no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a976e9b5ec50b7352b67ffcd5eaefb
Autor:
Lawrence Humphreys, Joaquín Rueda, Diego Delgado, José Manuel Ferrández, Eduardo Fernández, Alejandro Garcia Moll, Alicia R. Gascón
Publikováno v:
Neurocomputing. 114:9-14
Since the initial demonstration of nerve excitation and the subsequent action potential generation by Hodgkin and Huxley in 1952, most efforts in modulating or restoring neural activity to cure diseases or injury have concentrated on using neural int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::309386d9f34727d07d8c4ef69b5943b2
https://doi.org/10.1016/j.neucom.2012.08.046
https://doi.org/10.1016/j.neucom.2012.08.046
Publikováno v:
Scientific Reports
The neuronal synapse is comprised of several distinct zones, including presynaptic vesicle zone (SVZ), active zone (AZ) and postsynaptic density (PSD). While correct relative positioning of these zones is believed to be essential for synaptic functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a146546f71ab3d95b294e94bc58ba05
https://pubmed.ncbi.nlm.nih.gov/26951792
https://pubmed.ncbi.nlm.nih.gov/26951792
Publikováno v:
Scientific Reports. 6
Scientific Reports 6: Article number: 2270310.1038/srep22703; published online: March082016; updated: May312016 This Article contains errors. In the Results section, “In contrast to the cortical neurons12, activity blockade did not result in a decr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52a642977ffe0f0b7106e5a800ca4ca6
https://doi.org/10.1038/srep26422
https://doi.org/10.1038/srep26422
Publikováno v:
Glebov, O O, Cox, S, Humphreys, L & Burrone, J 2016, ' Neuronal activity controls transsynaptic geometry ', Scientific Reports, vol. 6, 22703 . https://doi.org/10.1038/srep22703
Scientific Reports
Scientific Reports
The neuronal synapse is comprised of several distinct zones, including presynaptic vesicle zone (SVZ), active zone (AZ) and postsynaptic density (PSD). While correct relative positioning of these zones is believed to be essential for synaptic functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eba92f1487e5d54a4a32b8692b6d764a
https://kclpure.kcl.ac.uk/en/publications/04bd1b08-d86d-4497-a7d6-677c8565272b
https://kclpure.kcl.ac.uk/en/publications/04bd1b08-d86d-4497-a7d6-677c8565272b
Autor:
Christopher N. G. Anderson, Seth G. N. Grant, Luis M. Valor, Paul Charlesworth, Lawrence Humphreys
Publikováno v:
Proceedings of the National Academy of Sciences. 104:4658-4663
Global biological datasets generated by genomics, transcriptomics, and proteomics provide new approaches to understanding the relationship between the genome and the synapse. Combined transcriptome analysis and multielectrode recordings of neuronal n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683e07b78d8af04426f79ace251cf632
https://doi.org/10.1073/pnas.0609071104
https://doi.org/10.1073/pnas.0609071104
Autor:
Ariadna Díaz-Tahoces, Antonio Martínez-Álvarez, Eduardo Fernández, Alejandro García-Moll, Jose Angel Bolea, Lawrence Humphreys
Publikováno v:
Artificial Computation in Biology and Medicine ISBN: 9783319189130
IWINAC (1)
IWINAC (1)
One of the many important functions the brain carries out is interpreting the external world. For this, one sense that most mammals rely on is vision. The first stage of the visual system is the image processing whose capture takes place in the retin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74eaadf34fbab2abcffd7d9f8bdfda68
https://doi.org/10.1007/978-3-319-18914-7_23
https://doi.org/10.1007/978-3-319-18914-7_23