Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Lawrence H Cheung"'
Autor:
Ana Alvarez de Cienfuegos, Lawrence H Cheung, Khalid A Mohamedali, Timothy G Whitsett, Jeffrey A Winkles, Walter N Hittelman, Michael G Rosenblum
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Antibody-drug conjugates are an exceptional and useful therapeutic tool for multiple diseases, particularly for cancer treatment. We previously showed that the fusion of the serine protease granzyme B (GrB), the effector molecule or T and
Externí odkaz:
https://doaj.org/article/12c629aa49a34d43add526d6194f842b
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6691 (2009)
BACKGROUND: There is a need for drug delivery systems (DDS) that can enhance cytosolic delivery of anti-cancer drugs trapped in the endo-lysosomal compartments. Exposure of cells to specific photosensitizers followed by light exposure (photochemical
Externí odkaz:
https://doaj.org/article/ff68eee718fe483184c85fb9101cdc9d
Autor:
Michael G. Rosenblum, Gregory P. Adams, Chun Li, Kim Boland, Lawrence H. Cheung, John W. Marks, Xiaoxia Wen, Walter N. Hittelman, Chiyi Xiong, Stephen I. Rudnick, Qian Huang, James D. Marks, Yu Cao
PDF file - 1631KB, Competitive cytotoxicity of the scFv/rGel in the presence of free Her2/neu ECD.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0375c8fc8ae771cf5b7dcb7d8b877ba
https://doi.org/10.1158/1535-7163.22498744
https://doi.org/10.1158/1535-7163.22498744
Autor:
Michael G. Rosenblum, Nhan L. Tran, Jeffrey A. Winkles, Walter N. Hittelman, Yuan Qi, Xiudong Lei, Janine LoBello, Lawrence H. Cheung, Mary Migliorini, Yu Cao, Ana Maria Gonzalez-Angulo, Khalid A. Mohamedali, Hong Zhou
Supplementary Figures 1-8. Supplementary Figure 1: TWEAK is internalized and degraded following binding to Fn14-positive cells Supplementary Figure 2: Surface plasmon resonance analysis of TWEAK Supplementary Figure 3: GrB-TWEAK specifically internal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f699c8a82be2f270e9b2b2f6c66f0b
https://doi.org/10.1158/1535-7163.22501878.v1
https://doi.org/10.1158/1535-7163.22501878.v1
Autor:
Michael G. Rosenblum, Gregory P. Adams, Chun Li, Kim Boland, Lawrence H. Cheung, John W. Marks, Xiaoxia Wen, Walter N. Hittelman, Chiyi Xiong, Stephen I. Rudnick, Qian Huang, James D. Marks, Yu Cao
PDF file - 1215KB, Enzymatic activities of AST and LDH in the serum of mice with or without tumors, treated with rGel, MH3-B1/rGel or B1D3/rGel.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa6eb57746e83a9d2821898ca3fa9e1
https://doi.org/10.1158/1535-7163.22498732
https://doi.org/10.1158/1535-7163.22498732
Autor:
Michael G. Rosenblum, Gregory P. Adams, Chun Li, Kim Boland, Lawrence H. Cheung, John W. Marks, Xiaoxia Wen, Walter N. Hittelman, Chiyi Xiong, Stephen I. Rudnick, Qian Huang, James D. Marks, Yu Cao
PDF file - 1877KB, Statistical comparisons of Tissue-to-Muscle Ratio (tumor or liver to muscle ratio) of IRDye800-MH3-B1/rGel and IRDye800-B1D3/rGel after 24h (A) and 72h (B) injection to BT474 M1 xenograft tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa2ae15289b7e5f5eb22fd068fa49be
https://doi.org/10.1158/1535-7163.22498735.v1
https://doi.org/10.1158/1535-7163.22498735.v1
Autor:
Michael G. Rosenblum, Nhan L. Tran, Jeffrey A. Winkles, Walter N. Hittelman, Yuan Qi, Xiudong Lei, Janine LoBello, Lawrence H. Cheung, Mary Migliorini, Yu Cao, Ana Maria Gonzalez-Angulo, Khalid A. Mohamedali, Hong Zhou
Supplementary materials and methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dda76b441c2c569bfa40e6b02eda224
https://doi.org/10.1158/1535-7163.22501869.v1
https://doi.org/10.1158/1535-7163.22501869.v1
Autor:
Michael G. Rosenblum, Gregory P. Adams, Chun Li, Kim Boland, Lawrence H. Cheung, John W. Marks, Xiaoxia Wen, Walter N. Hittelman, Chiyi Xiong, Stephen I. Rudnick, Qian Huang, James D. Marks, Yu Cao
PDF file - 1372KB, Quantification of Her2/neu level shed from Her2/neu positive cells. A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688ffa20c53209af9b1184843cc9941c
https://doi.org/10.1158/1535-7163.22498741
https://doi.org/10.1158/1535-7163.22498741
Supplementary Figures - PDF file 791K, Supplementary Figure 1. Representative image showing selective detection of CD-31+ pixels using MetaMorph 7.7 imaging software. The original image is shown in Figure 6B. Supplementary Figure 2. Original whole ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9130f4a6762da51322bfecbe0a8eff57
https://doi.org/10.1158/1535-7163.22498407.v1
https://doi.org/10.1158/1535-7163.22498407.v1
Autor:
Michael G. Rosenblum, Gregory P. Adams, Chun Li, Kim Boland, Lawrence H. Cheung, John W. Marks, Xiaoxia Wen, Walter N. Hittelman, Chiyi Xiong, Stephen I. Rudnick, Qian Huang, James D. Marks, Yu Cao
PDF file - 4112KB, Competitive internalization assay of 20nM immunotoxins with different concentration of the Her2/neu ECD on BT474 M1 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae80aa1df81be5fedd16ca539effcb86
https://doi.org/10.1158/1535-7163.22498747
https://doi.org/10.1158/1535-7163.22498747