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pro vyhledávání: '"Lawrence G. Raisz"'
Basic principles - cell biology biochemistry bone re-modelling and mineral homeostasis the hormones of bone other systemic hormones that influence bone metabolism local regulators of bone molecular mechanisms of metabolic bone diseases pharmacologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e246d847c36e8ba929b5abda9f8ad5bf
https://doi.org/10.1016/c2015-1-01622-2
https://doi.org/10.1016/c2015-1-01622-2
Autor:
Lawrence G. Raisz
Publikováno v:
Journal of periodontology. 50
Autor:
Anne M. Kenny, Richard Feinn, Jane E. Kerstetter, Lawrence G. Raisz, T. V. Rajan, K. Kuruvilla
Publikováno v:
Osteoporosis International. 22:217-221
We evaluated the effect of BMD on fracture risk prediction using FRAX® among Asian Indian men when used in conjunction with clinical risk factors. A majority of our subjects were either osteopenic or osteoporotic, and their fracture risk increased w
Publikováno v:
Journal of Bone and Mineral Research. 4:313-324
We have developed a bone organ culture system that mineralizes in vitro. Fetal rat parietal bones (20 days old) were cultured in a chemically defined serum-free medium containing physiological 3 mM phosphate. During 5 days in culture, calcium content
Autor:
Bradley N. Delman, Hiroshi Kawaguchi, Lawrence G. Raisz, Cynthia B. Alander, Olga Voznesensky, Carol C. Pilbeam
Publikováno v:
Journal of Bone and Mineral Research. 10:406-414
Prostaglandins (PGs) have been postulated to amplify their own production by stimulating cyclic adenosine monophosphate activity, which in turn stimulates PG production. We examined regulation of messenger RNA levels for the inducible and constitutiv
Publikováno v:
Journal of Bone and Mineral Research. 9:1935-1943
We previously showed that prostaglandin E2 (PGE2) can selectively inhibit collagen synthesis and gene transcription in the immortalized rat osteoblastic clonal cell line Py1a, particularly in the presence of insulin-like growth factor I (IGF-I). In t
Publikováno v:
Journal of Bone and Mineral Research. 4:449-458
Chronic low doses of hPTH-(1–34) stimulate bone growth in rats in vivo. The objective of these studies was to determine if the anabolic effect of hPTH-(1–34) on rat bone in vivo is dependent on an initial stimulation of resorption by blocking res
Publikováno v:
Journal of Bone and Mineral Research. 6:1339-1344
1,25-Dihydroxyvitamin D3 [1,25-(OH)2D3] was tested for its effects on prostaglandin E2 (PGE2) production and bone resorption in cultured mouse parietal bones. We found that at 24 h 1,25-(OH)2D3 increased 45Ca release but did not affect PGE2 productio
Publikováno v:
Journal of Bone and Mineral Research. 6:1037-1042
Potassium peroxydiphosphate (KPDP) is a slowly hydrolyzed pyrophosphate analog that can release hydrogen peroxide during hydrolysis. We tested its effects on the resorption of cultured fetal rat long bones as measured by the release of previously inc
Publikováno v:
Journal of Bone and Mineral Research. 9:247-253
Thyroid hormones can stimulate bone resorption both directly and indirectly by increasing endogenous prostaglandin (PG) synthesis. Because 3,5,3'-triiodothyroacetic acid (Triac, Tiratricol) can bind to nuclear thyroid hormone receptors with high affi