Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Lawrence E. Thibault"'
Publikováno v:
The Neuroscientist. 4:202-215
Diffuse axonal injury (DAI) is a frequent form of traumatic brain injury in which a clinical spectrum of in creasing injury severity is paralleled by progressively increasing amounts of axonal damage in the brain. When less severe, DAI is associated
Publikováno v:
Journal of Neuroscience Research. 52:220-229
A biomechanical in vitro model of traumatic brain injury was used to examine cellular response to physical insults and the underlying mechanisms that lead to cell dysfunction. A cell shearing injury device was used to deform human NTera-2 neurons at
Autor:
Torg Js, Brian Sennett, Naranja Rj, Thomas A. Corcoran, Helene Pavlov, Priano S, Lawrence E. Thibault
Publikováno v:
Journal of Neurosurgery. 87:843-850
✓ One hundred ten cases of the transient neurological phenomenon, cervical cord neurapraxia (CCN), are presented. The authors established a classification system for CCN, developed a new computerized measurement technique for magnetic resonance (MR
Autor:
Lynne E. Bilston, Lawrence E. Thibault
Publikováno v:
International Journal of Crashworthiness. 2:207-218
This paper describes the construction and validation of a physical model of the human cervical spinal column. The model incorporates a model spinal cord whose deformation may be measured during a simulated impact. The mechanical properties of the mod
The Biochemical Pathway Mediating the Proliferative Response of Bone Cells to a Mechanical Stimulus*
Autor:
Adam S. Landsman, Lawrence E. Thibault, Thomas M. Reilly, John L. Williams, J. Rush S. Fisher, Stuart E. Levine, Carl T. Brighton, John R. Corsetti
Publikováno v:
The Journal of Bone & Joint Surgery. 78:1337-47
Calvarial bone cells of rats were subjected to either a cyclic biaxial strain of 0.17 per cent (1700 microstrain) or a hydrostatic pressure of 2.5, five, or ten pounds per square inch (17.2, 34.5, or sixty-nine kilopascals). The frequency was held co
Publikováno v:
International Journal of Impact Engineering. 15:535-560
Summary A review of research on brain trauma mechanisms operative during head impact is presented from a clinically relevant biomechanical perspective. Emphasis is placed on microscopic mechanisms, gleaned from isolated neural tissue and cellular bio
Autor:
Joseph S. Torg, Lawrence E. Thibault
Publikováno v:
Operative Techniques in Sports Medicine. 1:183-186
Research findings and clinical experience obtained over the past 20 years have clearly established the principles of brain resuscitation in the management of closed head injuries. It is proposed that with regard to resulting morbidity, the same patho
Publikováno v:
Journal of Biomechanical Engineering. 115:160-168
When bovine pulmonary artery endothelial cells in culture are subjected to mechanical strain, their physiology is altered. Experimentally, this mechanical strain is generated by increased tension in the substrate to which the cells are attached and r
Publikováno v:
Journal of Biomechanics. 25:917-923
The head injury criterion (HIC) is currently the government-accepted head injury indicator. The HIC is not injury-specific, does not relate to injury severity, nor does it take into account variations in the brain mass or load direction. This report