Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lawrence C. Sellin"'
Autor:
Kathleen M. Coakley, Joseph J. McArdle, Kormakur Hognason, Joseph G. Potian, Lawrence C. Sellin
Publikováno v:
Neuropharmacology. 50:345-353
Effectiveness against chloroquine-resistant Plasmodia makes mefloquine a widely used antimalarial drug. However, mefloquine's neurologic effects offset this therapeutic advantage. Cellular actions which might contribute to the neurologic effects of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec711856709f7f94da5b015506cbb31
https://doi.org/10.1016/j.neuropharm.2005.09.011
https://doi.org/10.1016/j.neuropharm.2005.09.011
Autor:
Joseph J. McArdle, Joseph G. Potian, Kathleen M. Coakley, Mary C. Quinones-Lopez, Kormakur Hognason, Lawrence C. Sellin, Clint A. Rosenfeld, Lester G. Sultatos
Publikováno v:
Neuropharmacology. 49(8)
Mefloquine is effective against drug-resistant Plasmodium falciparum. This property, along with its unique pharmacokinetic profile, makes mefloquine a widely prescribed antimalarial drug. However, mefloquine has neurologic effects which offset its th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd249a8f002297f1204c198ce844f4ab
https://pubmed.ncbi.nlm.nih.gov/16081111
https://pubmed.ncbi.nlm.nih.gov/16081111
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 34(2)
The actions of the K+ channel blocker, 3,4-diaminopyridine (3,4-DAP), were studied in the rat extensor digitorum longus (EDL) muscle following local inhibition of neuromuscular transmission by botulinum neurotoxin (BoNT). Local paralysis of the EDL m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8c028956174e026400d590bd8f079b
https://pubmed.ncbi.nlm.nih.gov/8711757
https://pubmed.ncbi.nlm.nih.gov/8711757
Publikováno v:
Pharmacologytoxicology. 70(6 Pt 1)
The neuromuscular effects of a peptide toxin (peptide I) from venom of Trimeresurus wagleri were investigated using the rat extensor digitorum longus muscle/peroneal nerve preparation. Sub-micromolar concentrations depressed endplate currents (EPCs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ab4ceed15fca3d262413db41930647
https://pubmed.ncbi.nlm.nih.gov/1359525
https://pubmed.ncbi.nlm.nih.gov/1359525
Autor:
Lawrence C. Sellin, Nick Sperelakis
Publikováno v:
Experimental Neurology. 62:605-617
The resting membrane potential (Em) of skeletal muscle fibers from dystrophic mice was depolarized about 14 mV compared to normal muscles. By experiments done in the presence and absence of ouabain, it was determined that the contribution of the elec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f76521696f454395c1ad14377fd6b8
https://doi.org/10.1016/0014-4886(78)90272-8
https://doi.org/10.1016/0014-4886(78)90272-8
Autor:
Lawrence C. Sellin, Joseph J. McArdle
Publikováno v:
Experimental Neurology. 55:483-492
The extensor digitorum longus muscle (EDL) of the rat was denervated bilaterally by crushing the right and left deep peroneal nerves. Five days later, a Silastic cuff containing 0.1% colchicine was implanted around the left sciatic nerve (experimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e623b1e16e61187fb311cb4e2477495
https://doi.org/10.1016/0014-4886(77)90016-4
https://doi.org/10.1016/0014-4886(77)90016-4
Autor:
Lawrence C. Sellin
Publikováno v:
Military Medicine. 149:12-16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24ac2dbb3b3b46482aab55174f520e62
https://doi.org/10.1093/milmed/149.1.12
https://doi.org/10.1093/milmed/149.1.12
Autor:
Lawrence C. Sellin
Publikováno v:
Trends in Pharmacological Sciences. 6:80-82
In this review, Lawrence Sellin describes the botulinal neurotoxins which occur as seven immunologically distinct types A–G and may bind to a ‘proteoglycan component' on the extracellular face of the nerve terminal membrane. Following binding the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78246adb76a6acdfab3276e1286e8b08
https://doi.org/10.1016/0165-6147(85)90033-1
https://doi.org/10.1016/0165-6147(85)90033-1
Autor:
Lawrence C. Sellin
Botulism results from the action of a protein neurotoxin (mol. wt. congruent to 150,000) produced by the bacterium Clostridium botulinum, of which there are eight known strains. Botulinum neurotoxin is the most potent biological toxin known, having a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d11a37ac689a4ef2e345e1899846cee
https://doi.org/10.21236/ada094643
https://doi.org/10.21236/ada094643
Publikováno v:
Experimental neurology. 56(1)
Male rats were made hyperthyroid by daily injections by Na-3,3′,5′-triiodo- l -thyronine (T3). Twenty-four hours after the 10th injection, the fast-twitch extensor digitorum longus (extensor) and the slow-twitch soleus muscles were excised from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b32ef5db1327458c4666d0e35bbf70
https://pubmed.ncbi.nlm.nih.gov/862688
https://pubmed.ncbi.nlm.nih.gov/862688