Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Lawrence C. Rosenberg"'
Publikováno v:
Imagination and Healing ISBN: 9781315227450
Imagination and Healing
Imagination and Healing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91bf7e9595e5a1c46d69a534db7b2f42
https://doi.org/10.4324/9781315227450-8
https://doi.org/10.4324/9781315227450-8
Publikováno v:
Journal of Biological Chemistry. 274:12454-12460
Decorin is ubiquitously distributed in the extracellular matrix of mammals and a member of the proteoglycan family characterized by a core protein dominated by leucine-rich repeat motifs. We show here that decorin extracted from bovine tissues under
Autor:
Mirela Ionescu, F Nelson, G L Fraser, Sheila Laverty, A. Robin Poole, Leif Dahlberg, Isabelle Pidoux, Paul Dieppe, Lawrence C. Rosenberg, Michael Tanzer, Brooks E, A. Reiner
Publikováno v:
Journal of Clinical Investigation. 102:2115-2125
There is evidence to suggest that the synthesis of type II collagen is increased in osteoarthritis (OA). Using an immunoassay, we show that the content of the C-propeptide of type II procollagen (CPII), released extracellularly from the newly synthes
Autor:
R. Lalic, Carolyn Webber, Lawrence C. Rosenberg, A. Cartman, A R Poole, E. De Miguel, J.-Y. Leroux, Alexei Guerassimov, Yiping Zhang
Publikováno v:
Journal of Clinical Investigation. 101:1678-1686
Our previous work showed that the proteoglycan aggrecan can induce erosive polyarthritis and spondylitis in BALB/c mice, and that the G1 domain of the proteoglycan aggrecan (G1) is the arthritogenic region. In this study, two T cell epitopes residing
Autor:
A. Robin Poole, Mirela Ionescu, Earl R. Bogoch, Lawrence C. Rosenberg, Peter J. Roughley, A Reiner
Publikováno v:
Journal of Orthopaedic Research. 14:681-689
The study was designed to determine the contents and distributions of the proteoglycans decorin and biglycan in adult human femoral condylar cartilage and whether these may change in osteoarthritis. New radioimmunoassays were established using peptid
Publikováno v:
Journal of Orthopaedic Research. 14:334-339
Previous work has shown that alterations in proteoglycan aggregates are among the first changes detected with aging, disuse, and degeneration of articular cartilage, yet the cause or causes of these alterations remain unknown. To determine if differe
Autor:
Lawrence C. Rosenberg, Joanne U. Gaw, Peter J. Neame, Thomas J. Koob, Frank Barry, Janette U. Gaw
Publikováno v:
Journal of Biological Chemistry. 270:20516-20524
In the hyaluronan binding region (HABR) peptide of aggrecan, there is a marked increase in the level of keratan sulfate (KS) during aging. To determine the sites of KS attachment, KS-containing peptides were prepared from HABRs from immature and matu
Publikováno v:
Wound Repair and Regeneration. 2:270-276
Previous studies have shown that a simple analog of extracellular matrix delays wound contraction and, if seeded with keratinocytes, inhibits scar synthesis by inducing partial regeneration of the dermis and the epidermis in full-thickness skin wound
Publikováno v:
Microscopy Research and Technique. 28:398-408
Biochemical and biophysical studies have shown that the composition and sedimentation velocity of cartilage proteoglycans change with age, but these investigations cannot demonstrate the alterations in molecular structure responsible for these change