Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Lawrence C. Myers"'
Autor:
Jeffrey M Hollomon, Zhongle Liu, Scott F Rusin, Nicole P Jenkins, Allia K Smith, Katja Koeppen, Arminja N Kettenbach, Lawrence C Myers, Deborah A Hogan
Publikováno v:
PLoS Genetics, Vol 18, Iss 1, p e1009622 (2022)
Ssn3, also known as Cdk8, is a member of the four protein Cdk8 submodule within the multi-subunit Mediator complex involved in the co-regulation of transcription. In Candida albicans, the loss of Ssn3 kinase activity affects multiple phenotypes inclu
Externí odkaz:
https://doaj.org/article/54bd89527e8c488da2f49df4c9139036
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006373 (2016)
Filamentous growth is a hallmark of C. albicans pathogenicity compared to less-virulent ascomycetes. A multitude of transcription factors regulate filamentous growth in response to specific environmental cues. Our work, however, suggests the evolutio
Externí odkaz:
https://doaj.org/article/382f276dae3343bcb2c56ea266b5e36d
Publikováno v:
PLoS Pathogens, Vol 11, Iss 2, p e1004614 (2015)
Externí odkaz:
https://doaj.org/article/5c3a28664e984bd684574e8710c2a37b
Autor:
Zhongle Liu, Lawrence C. Myers, Jeffrey M. Hollomon, Smith Ak, Deborah A. Hogan, Nicole P. Jenkins, Scott F. Rusin, Katja Koeppen, Arminja N. Kettenbach
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 18, Iss 1, p e1009622 (2022)
PLoS Genetics, Vol 18, Iss 1, p e1009622 (2022)
Ssn3, also known as Cdk8, is a member of the four protein Cdk8 submodule within the multi-subunit Mediator complex involved in the co-regulation of transcription. In Candida albicans, the loss of Ssn3 kinase activity affects multiple phenotypes inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38219b429c875eb2f7d778e5d986133
https://doi.org/10.1101/2021.06.10.447844
https://doi.org/10.1101/2021.06.10.447844
Autor:
John Haran, Hannah Boyle, Karsten Hokamp, Tim Yeomans, Zhongle Liu, Michael Church, Alastair B Fleming, Matthew Z Anderson, Judith Berman, Lawrence C Myers, Derek J Sullivan, Gary P Moran
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004658 (2014)
The TLO genes are a family of telomere-associated ORFs in the fungal pathogens Candida albicans and C. dubliniensis that encode a subunit of the Mediator complex with homology to Med2. The more virulent pathogen C. albicans has 15 copies of the gene
Externí odkaz:
https://doaj.org/article/7d031443077a424cacf2e2504d266711
Autor:
Allia K Lindsay, Diana K Morales, Zhongle Liu, Nora Grahl, Anda Zhang, Sven D Willger, Lawrence C Myers, Deborah A Hogan
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004567 (2014)
Candida albicans biofilm formation is a key virulence trait that involves hyphal growth and adhesin expression. Pyocyanin (PYO), a phenazine secreted by Pseudomonas aeruginosa, inhibits both C. albicans biofilm formation and development of wrinkled c
Externí odkaz:
https://doaj.org/article/5580a5a459da42388b7870b257149720
Autor:
Zhongle Liu, Lawrence C Myers
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38416 (2012)
The Mediator complex transmits activation signals from DNA bound transcription factors to the core transcription machinery. In addition to its canonical role in transcriptional activation, recent studies have demonstrated that S. cerevisiae Mediator
Externí odkaz:
https://doaj.org/article/00dc4b2459e74f6499a135a2047d1d70
Publikováno v:
Current genetics. 65(3)
Mediator complex has recently emerged as an important regulator of gene expression in pathogenic fungi. Mediator is a multi-subunit complex of polypeptides involved in transcriptional activation in eukaryotes, with roles including preinitiation compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a66840146f3a0af43e9bd852a9b300d
https://pubmed.ncbi.nlm.nih.gov/30637479
https://pubmed.ncbi.nlm.nih.gov/30637479
Farnesol, a quorum-sensing molecule, inhibits Candida albicans hyphal formation, affects its biofilm formation and dispersal, and impacts its stress response. Several aspects of farnesol's mechanism of action remain incompletely uncharacterized. Amon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270d4f31a3fee7624ddcf07f9ef18ba0
https://europepmc.org/articles/PMC6201089/
https://europepmc.org/articles/PMC6201089/
Farnesol, a quorum-sensing molecule, inhibits C. albicans hyphal formation, affects its biofilm formation and dispersal, and impacts its stress response. Several aspects of farnesol’s mechanism of action remain incompletely uncharacterized. Among t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefd2f20a05057ed7ff490c92d24f82d
https://doi.org/10.1101/320028
https://doi.org/10.1101/320028