Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lawrence C. Huang"'
Autor:
Lawrence C. Huang, John C. Crabbe, Jason P. Schlumbohm, Gian D. Greenberg, Wyatt R. Hack, Pamela Metten, Stephanie E. Spence
Publikováno v:
Alcohol (Fayetteville, N.Y.). 68
Despite acceptance that risk for alcohol-use disorder (AUD) has a large genetic component, the identification of genes underlying various components of risk for AUD has been hampered in humans, in part by the heterogeneity of expression of the phenot
Autor:
Angela R. Ozburn, Jason P. Schlumbohm, John C. Crabbe, Lawrence C. Huang, Amanda M. Barkley-Levenson, Stephanie E. Spence, Wyatt R. Hack, Pamela Metten
Publikováno v:
Pharmacology, biochemistry, and behavior. 160
Background There is a serious public health need for better understanding of alcohol use disorder disease mechanisms and for improved treatments. At this writing, only three drugs are approved by the Food and Drug Administration as medications to tre
Autor:
Amanda M. Barkley-Levenson, Pamela Metten, Andy J. Cameron, Stephanie E. Spence, Lawrence C. Huang, Matthew M. Ford, Jason P. Schlumbohm, John C. Crabbe, Tamara J. Phillips, John K. Belknap
Publikováno v:
Genes, Brain and Behavior. 13:236-246
Drinking in the dark (DID) is a limited access ethanol-drinking phenotype in mice. High Drinking in the Dark (HDID-1) mice have been bred for 27 selected generations (S27) for elevated blood ethanol concentrations (BECs) after a 4-h period of access
Autor:
Lawrence C. Huang, Andy J. Cameron, Jason P. Schlumbohm, John C. Crabbe, Stephanie E. Spence, Pamela Metten, Amanda M. Barkley-Levenson
Publikováno v:
Alcohol. 47:381-389
Withdrawal Seizure-Prone (WSP) and Withdrawal Seizure-Resistant (WSR) mouse lines were bidirectionally selectively bred, respectively, to have severe or mild ethanol withdrawal handling-induced convulsions (HICs) after cessation of 3 days of ethanol
Autor:
John C. Crabbe, Lawrence C. Huang, Stephanie E. Spence, Jason P. Schlumbohm, Gian D. Greenberg, Angela R. Ozburn, Pamela Metten
Withdrawal after chronic ethanol (EtOH) affects body temperature, goal-directed behavior and motor function in mice and increases general central nervous system excitability. Nest-building tests have been used to assay these states but to this point
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eeea54f18f652e6a17811acd24231d1
https://europepmc.org/articles/PMC5456259/
https://europepmc.org/articles/PMC5456259/
Autor:
John C. Crabbe, Lawrence C. Huang, Lauren C. Kruse, Stephanie E. Spence, Andy J. Cameron, Jason P. Schlumbohm, Pamela Metten, Alexandre M. Colville
Publikováno v:
Alcoholism: Clinical and Experimental Research. 36:1152-1161
Mouse lines are being selectively bred in replicate for high blood ethanol concentrations (BECs) achieved after limited access of ethanol (EtOH) drinking early in the circadian dark phase. High Drinking in the Dark-1 (HDID-1) mice are in selected gen
Autor:
Andy J. Cameron, Jason P. Schlumbohm, John C. Crabbe, Lawrence C. Huang, Pamela Metten, Justin S. Rhodes, Stephanie E. Spence, Amanda M. Barkley-Levenson, Deborah A. Finn
Ethanol Withdrawal-Associated Drinking and Drinking in the Dark: Common and Discrete Genetic Contributions Individual mice differ in the dose of ethanol they will ingest voluntarily when it is offered during limited access periods in the circadian da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5317e30bcdde4ee02ac160408d8aff0f
https://europepmc.org/articles/PMC3923583/
https://europepmc.org/articles/PMC3923583/
Publikováno v:
Alcohol and alcoholism (Oxford, Oxfordshire). 47(5)
Aims: Intermittent access (IA) to an alcohol (ethanol) solution can lead rats to higher ethanol intakes than continuous access, and a recent report showed increased drinking in C57BL/6J mice offered 20% ethanol vs. water 3X/week (Prior studies have o
Autor:
Lawrence C. Huang, Alexandre M. Colville, Andy J. Cameron, Jason P. Schlumbohm, Pamela Metten, John C. Crabbe, Lauren C. Kruse, Stephanie E. Spence
Publikováno v:
Alcoholism, clinical and experimental research. 36(7)
Background Mouse lines are being selectively bred in replicate for high blood ethanol concentrations (BECs) achieved after a short period of ethanol (EtOH) drinking early in the circadian dark phase. High Drinking in the Dark-1 (HDID-1) mice were in