Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lawrence C. Creemer"'
Autor:
Frank J. Wessels, Yap Maurice C, Natalie C. Giampietro, Gerrit J. deBoer, Lawrence C. Creemer, Lambert William Thomas, Scott Castetter, Yelena Adelfinskaya
Publikováno v:
Pest Management Science. 73:752-760
BACKGROUND The adrenergic mode of action was investigated for the development of potential new insecticides. Clonidine-related analogs were tested against Myzus persicae (Sulzer) and Bemisia tabaci (Gennadius). Clonidine analogs lack translation owin
Autor:
Qiang Yang, Lawrence C. Creemer, Peter L. Johnson, James A. Knobelsdorf, Benjamin M. Nugent, Carl V. De Amicis, Sarah Ryan, Elizabeth O. McCusker, Gregory T. Whiteker, Nakyen Choy, Beth A. Lorsbach, Nicole M. Hewlett, Fangzheng Li, Belgin Canturk, Nicholas R. Babij, Michelle Smith
Publikováno v:
Organic Process Research & Development. 20:661-667
The 1H and 13C NMR chemical shifts of 48 industrially preferred solvents in six commonly used deuterated NMR solvents (CDCl3, acetone-d6, DMSO-d6, acetonitrile-d3, methanol-d4, and D2O) are reported. This work supplements the compilation of NMR data
Autor:
Lawrence C, Creemer, Natalie C, Giampietro, William, Lambert, Maurice C, Yap, Gerrit J, deBoer, Yelena, Adelfinskaya, Scott, Castetter, Frank J, Wessels
Publikováno v:
Pest management science. 73(4)
The adrenergic mode of action was investigated for the development of potential new insecticides. Clonidine-related analogs were tested against Myzus persicae (Sulzer) and Bemisia tabaci (Gennadius). Clonidine analogs lack translation owing to a poss
Publikováno v:
Organic Process Research & Development. 8:593-596
The preparation of Elanco Animal Health immunopotentiator (S)-ethyl-1-(2-thiopheneacetyl)-3-piperidinecarboxylate (1) is described. The synthesis includes a new resolution of racemic ethyl nipecotate with dibenzoyl-l-tartaric acid. The resolved salt
Publikováno v:
The Journal of Antibiotics. 53:171-178
In an effort to increase the insecticidal activity of the spinosyn family of naturally occurring macrolides, the 2'-, 3'- and 4'-O-desmethyl-O-acetyl analogs and the 2'-, 3'-, and 4'-O-desmethoxy analogs have been synthesized. These analogs were prep
Autor:
J. M. Greene, David A. Preston, Lawrence C. Creemer, F. T. Counter, Jonathan W. Paschal, R L Clemens, J G Amos, William E. Alborn, K A Sullivan, Herbert A. Kirst
Publikováno v:
Antimicrobial Agents and Chemotherapy. 39:1436-1441
Dirithromycin is the 9-N,11-O-oxazine adduct formed from 9(S)-erythromycylamine and 2-(2-methoxyethoxy)acetaldehyde in which the methoxyethoxymethyl substituent on the oxazine ring possesses the R configuration. Epidirithromycin is its isomer in whic
Autor:
Stephen H. Larsen, Jorge Rios Steiner, Jonathan W. Paschal, Jon Clardy, Herbert A. Kirst, John L. Occolowitz, Lawrence C. Creemer, Emil B. Lobkovsky
Publikováno v:
The Journal of Antibiotics. 48:990-996
A new member of the spiroketal-containing macrolide class of fermentation-derived natural products was isolated from mycelial extracts of Streptomyces diastatochromogenes. The principal component, A82548A, was shown to possess a 22-membered macrolide
Autor:
Donnis M. Berry, John L. Occolowitz, Julie A. Wind, Jonathan W. Paschal, Lawrence C. Creemer, Alvin L. Donoho, Herbert A. Kirst
Publikováno v:
Journal of Agricultural and Food Chemistry. 42:1219-1222
Two substances, designated T-1 and T-2, were isolated during metabolism studies with tilmicosin, a new veterinary macrolide antibiotic. By combination of mass spectrometry and NMR spectroscopy, T-1 was identified as N-demethyltilmicosin and T-2 was a
Autor:
Emil B. Lobkovsky, John L. Occolowitz, Jon Clardy, Jonathan W. Paschal, Stephen H. Larsen, Lawrence C. Creemer, Herbert A. Kirst, J. L. Rios Steiner
Publikováno v:
ChemInform. 27
Publikováno v:
ChemInform. 28
New C-11 esters of the fermentation product wortmannin have been synthesized, with some of them further derivatized at C-17. The new esters show greater inhibition of isolated phosphatidylinositol 3-kinase and increased cell cytotoxicity in a rapidly