Zobrazeno 1 - 10
of 328
pro vyhledávání: '"Lawrence B Schwartz"'
Autor:
Qian Wang, Christin M Lepus, Harini Raghu, Laurent L Reber, Mindy M Tsai, Heidi H Wong, Ericka von Kaeppler, Nithya Lingampalli, Michelle S Bloom, Nick Hu, Eileen E Elliott, Francesca Oliviero, Leonardo Punzi, Nicholas J Giori, Stuart B Goodman, Constance R Chu, Jeremy Sokolove, Yoshihiro Fukuoka, Lawrence B Schwartz, Stephen J Galli, William H Robinson
Publikováno v:
eLife, Vol 8 (2019)
Osteoarthritis is characterized by articular cartilage breakdown, and emerging evidence suggests that dysregulated innate immunity is likely involved. Here, we performed proteomic, transcriptomic, and electron microscopic analyses to demonstrate that
Externí odkaz:
https://doaj.org/article/a7082ff767514c069f8232e435419a7c
Autor:
Do-Kyun Kim, Michael A Beaven, Joseph M Kulinski, Avanti Desai, Geethani Bandara, Yun Bai, Calman Prussin, Lawrence B Schwartz, Hirsh Komarow, Dean D Metcalfe, Ana Olivera
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162831 (2016)
Neoplastic accumulation of mast cells in systemic mastocytosis (SM) associates with activating mutations in the receptor tyrosine kinase KIT. Constitutive activation of tyrosine kinase oncogenes has been linked to imbalances in oxidant/antioxidant me
Externí odkaz:
https://doaj.org/article/3e0167753f844c6f8eb86c65501568f3
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114944 (2014)
The human tryptase locus on chromosome 16 contains one gene encoding only β-tryptase and another encoding either β-tryptase or the homologous α-tryptase, providing α:β gene ratios of 0:4, 1:3 or 2:2 in the diploid genome, these genotypes being o
Externí odkaz:
https://doaj.org/article/61412c8a2bc24ea488907b33baf8f8ff
Autor:
Peter Valent, Cem Akin, Karin Hartmann, Ivan Alvarez-Twose, Knut Brockow, Olivier Hermine, Marek Niedoszytko, Juliana Schwaab, Jonathan J. Lyons, Melody C. Carter, Hanneke Oude Elberink, Joseph H. Butterfield, Tracy I. George, Georg Greiner, Celalettin Ustun, Patrizia Bonadonna, Karl Sotlar, Gunnar Nilsson, Mohamad Jawhar, Frank Siebenhaar, Sigurd Broesby-Olsen, Selim Yavuz, Roberta Zanotti, Magdalena Lange, Boguslaw Nedoszytko, Gregor Hoermann, Mariana Castells, Deepti H. Radia, Javier I. Muñoz-Gonzalez, Wolfgang R. Sperr, Massimo Triggiani, Hanneke C. Kluin-Nelemans, Stephen J. Galli, Lawrence B. Schwartz, Andreas Reiter, Alberto Orfao, Jason Gotlib, Michel Arock, Hans-Peter Horny, Dean D. Metcalfe
Publikováno v:
HemaSphere, Vol 5, Iss 11, p e646 (2021)
Mastocytosis is a hematologic neoplasm characterized by expansion and focal accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone marrow (BM), spleen, liver, and gastrointestinal tract. The World Health Organization c
Externí odkaz:
https://doaj.org/article/baa6c70f9bed4d09abd7657782291f35
Autor:
Jack Chovanec, Ilker Tunc, Jason Hughes, Joseph Halstead, Allyson Mateja, Yihui Liu, Michael P. O’Connell, Jiwon Kim, Young Hwan Park, Qinlu Wang, Quang Le, Mehdi Pirooznia, Neil N. Trivedi, Yun Bai, Yuzhi Yin, Amy P. Hsu, Joshua McElwee, Sheryce Lassiter, Celeste Nelson, Judy Bandoh, Thomas DiMaggio, Julij Šelb, Matija Rijavec, Melody C. Carter, Hirsh D. Komarow, Vito Sabato, Joshua Steinberg, Kurt M. Hafer, Elizabeth Feuille, Christopher S. Hourigan, Justin Lack, Paneez Khoury, Irina Maric, Roberta Zanotti, Patrizia Bonadonna, Lawrence B. Schwartz, Joshua D. Milner, Sarah C. Glover, Didier G. Ebo, Peter Korošec, George H. Caughey, Erica H. Brittain, Ben Busby, Dean D. Metcalfe, Jonathan J. Lyons
Publikováno v:
Blood Advances. 7:1796-1810
Serum tryptase is a biomarker used to aid in the identification of certain myeloid neoplasms, most notably systemic mastocytosis, where basal serum tryptase (BST) levels >20 ng/mL are a minor criterion for diagnosis. Although clonal myeloid neoplasms
Autor:
Dean D. Metcalfe, Michel Arock, Hans-Peter Horny, Daniel A. Arber, K. Frank Austen, Stephen J. Galli, Petri T. Kovanen, Carsten Bindslev-Jensen, Sigurd Broesby-Olsen, Lawrence B. Schwartz, Alberto Orfao, Jason Gotlib, Knut Brockow, Massimo Triggiani, Celalettin Ustun, Hanneke C. Kluin-Nelemans, Tracy I. George, Luis Escribano, Wolfgang R. Sperr, Karl Sotlar, Olivier Hermine, Andreas Reiter, Gunnar Nilsson, Karin Hartmann, Cem Akin, Peter Valent
Supplemental Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fab2d00479074d7bcf5ce853e37e67b
https://doi.org/10.1158/0008-5472.22416261
https://doi.org/10.1158/0008-5472.22416261
Autor:
Dean D. Metcalfe, Michel Arock, Hans-Peter Horny, Daniel A. Arber, K. Frank Austen, Stephen J. Galli, Petri T. Kovanen, Carsten Bindslev-Jensen, Sigurd Broesby-Olsen, Lawrence B. Schwartz, Alberto Orfao, Jason Gotlib, Knut Brockow, Massimo Triggiani, Celalettin Ustun, Hanneke C. Kluin-Nelemans, Tracy I. George, Luis Escribano, Wolfgang R. Sperr, Karl Sotlar, Olivier Hermine, Andreas Reiter, Gunnar Nilsson, Karin Hartmann, Cem Akin, Peter Valent
Mastocytosis is a term used to denote a heterogeneous group of conditions defined by the expansion and accumulation of clonal (neoplastic) tissue mast cells in various organs. The classification of the World Health Organization (WHO) divides the dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642976114b1689d5e447040d93c61f30
https://doi.org/10.1158/0008-5472.c.6509508.v1
https://doi.org/10.1158/0008-5472.c.6509508.v1
Autor:
Lawrence B. Schwartz
Publikováno v:
Inflammatory Mechanisms in Allergic Diseases ISBN: 9780429134432
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef9fb28c3cd79be9021636c8011ddccb
https://doi.org/10.1201/9780429134432-32
https://doi.org/10.1201/9780429134432-32
Autor:
Lawrence B. Schwartz
Publikováno v:
Inflammatory Mechanisms in Allergic Diseases ISBN: 9780429134432
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8ed0b5f7f886cc453a90efdf054d4ae
https://doi.org/10.1201/9780429134432-4
https://doi.org/10.1201/9780429134432-4