Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Lawrence B Blyn"'
Autor:
David Metzgar, Mark W Frinder, Richard E Rothman, Stephen Peterson, Karen C Carroll, Sean X Zhang, Gideon D Avornu, Megan A Rounds, Heather E Carolan, Donna M Toleno, David Moore, Thomas A Hall, Christian Massire, Gregory S Richmond, Jose R Gutierrez, Rangarajan Sampath, David J Ecker, Lawrence B Blyn
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158186 (2016)
Bloodstream infection (BSI) and sepsis are rising in incidence throughout the developed world. The spread of multi-drug resistant organisms presents increasing challenges to treatment. Surviving BSI is dependent on rapid and accurate identification o
Externí odkaz:
https://doaj.org/article/be6f3a69455042f39f8a2c976a4b37c3
Autor:
Elena Jordana-Lluch, Heather E Carolan, Montserrat Giménez, Rangarajan Sampath, David J Ecker, M Dolores Quesada, Josep M Mòdol, Fernando Arméstar, Lawrence B Blyn, Lendell L Cummins, Vicente Ausina, Elisa Martró
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62108 (2013)
Achieving a rapid microbiological diagnosis is crucial for decreasing morbidity and mortality of patients with a bloodstream infection, as it leads to the administration of an appropriate empiric antimicrobial therapy. Molecular methods may offer a r
Externí odkaz:
https://doaj.org/article/c6faf736f9f94ab7bb80ca75ec953927
Autor:
Rangarajan Sampath, Niveen Mulholland, Lawrence B Blyn, Christian Massire, Chris A Whitehouse, Nicole Waybright, Courtney Harter, Joseph Bogan, Mary Sue Miranda, David Smith, Carson Baldwin, Mark Wolcott, David Norwood, Rachael Kreft, Mark Frinder, Robert Lovari, Irene Yasuda, Heather Matthews, Donna Toleno, Roberta Housley, David Duncan, Feng Li, Robin Warren, Mark W Eshoo, Thomas A Hall, Steven A Hofstadler, David J Ecker
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e36528 (2012)
Technology for comprehensive identification of biothreats in environmental and clinical specimens is needed to protect citizens in the case of a biological attack. This is a challenge because there are dozens of bacterial and viral species that might
Externí odkaz:
https://doaj.org/article/77b131fc90ce4ade82f71978c2d64786
Autor:
Mark W Eshoo, Chris A Whitehouse, Aysegul Nalca, Scott Zoll, Joseph A Ecker, Thomas A Hall, Thuy-Trang D Pennella, David D Duncan, Anjali Desai, Emily K Moradi, Karl Rudnick, Brian Libby, Raymond Ranken, Rangarajan Sampath, Steven A Hofstadler, David J Ecker, Lawrence B Blyn
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6342 (2009)
The genus Orthopoxvirus contains several species of related viruses, including the causative agent of smallpox (Variola virus). In addition to smallpox, several other members of the genus are capable of causing human infection, including monkeypox, c
Externí odkaz:
https://doaj.org/article/a068ef0d979f4587a7b9c9cca7ee0ee9
Autor:
Rangarajan Sampath, Kevin L Russell, Christian Massire, Mark W Eshoo, Vanessa Harpin, Lawrence B Blyn, Rachael Melton, Cristina Ivy, Thuy Pennella, Feng Li, Harold Levene, Thomas A Hall, Brian Libby, Nancy Fan, Demetrius J Walcott, Raymond Ranken, Michael Pear, Amy Schink, Jose Gutierrez, Jared Drader, David Moore, David Metzgar, Lynda Addington, Richard Rothman, Charlotte A Gaydos, Samuel Yang, Kirsten St George, Meghan E Fuschino, Amy B Dean, David E Stallknecht, Ginger Goekjian, Samuel Yingst, Marshall Monteville, Magdi D Saad, Chris A Whitehouse, Carson Baldwin, Karl H Rudnick, Steven A Hofstadler, Stanley M Lemon, David J Ecker
Publikováno v:
PLoS ONE, Vol 2, Iss 5, p e489 (2007)
Effective influenza surveillance requires new methods capable of rapid and inexpensive genomic analysis of evolving viral species for pandemic preparedness, to understand the evolution of circulating viral species, and for vaccine strain selection. W
Externí odkaz:
https://doaj.org/article/c99229be3506447dbf48c58321babbdc
Autor:
Gina Hong, Deanna A. Sutton, Christian Massire, Marissa J. White, Xinglun Liang, Brian L. Wickes, Jianmin Fu, Noah Lechtzin, Robert Lovari, Nathan P. Wiederhold, Richard S. Lee, Natalie E. West, Lawrence B. Blyn, Sean X. Zhang, Robin K. Avery, Heather Miller
Publikováno v:
Journal of Cystic Fibrosis. 16:e3-e7
Background Disseminated fungal infections are a known serious complication in individuals with cystic fibrosis (CF) following orthotopic lung transplantation. Aspergillus fumigatus and Scedosporium species are among the more common causes of invasive
Autor:
Richard E. Rothman, Bei Jia, Christian Massire, Sean X. Zhang, Heather E. Carolan, Heather Miller, Franco R. D'Alessio, Donna Toleno, Lawrence B. Blyn, David Metzgar, Robert Lovari
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 97:114988
The incidence of invasive fungal infections is on the rise worldwide due to the growth of the immunocompromised population. We report here the use of a diagnostic assay that utilizes a universal extraction method, broad spectrum PCR amplification and
Autor:
Thomas G. Laffler, David Metzgar, Lawrence B. Blyn, Donna Toleno, David J. Ecker, Teresa Wakefield, Karen C. Carroll, Natalie J. Kennel, Jose R. Gutierrez, Gregory S. Richmond, Andrea Bacconi, Richard E. Rothman, Christian Massire, Rangarajan Sampath, Heather E. Carolan, Mark Frinder, Michelle A. Baroldi, Megan A. Rounds, Stephen Peterson
Publikováno v:
Journal of Clinical Microbiology. 52:3164-3174
The rapid identification of bacteria and fungi directly from the blood of patients with suspected bloodstream infections aids in diagnosis and guides treatment decisions. The development of an automated, rapid, and sensitive molecular technology capa
Autor:
Michelle A. Toro, David J. Ecker, Rangarajan Sampath, Charles W. Stratton, Mark W. Eshoo, Thomas G. Laffler, Criziel D. Quinn, Lawrence B. Blyn, Lendell L. Cummins, Yi-Wei Tang, Donna Toleno, Colt M. McClain, Megan A. Rounds, Heather E. Carolan
Publikováno v:
Journal of Clinical Microbiology. 51:3535-3541
A prospective study was performed to determine the value of direct molecular testing of whole blood for detecting the presence of culturable and unculturable bacteria and yeasts in patients with suspected bloodstream infections. A total of 464 adult
Autor:
Christian Massire, Lawrence B. Blyn, Steven A. Hofstadler, Thomas A. Hall, Rangarajan Sampath, David J. Ecker, Mark W. Eshoo
Publikováno v:
Molecular Microbiology. :343-351
This chapter describes about a new technology for the identification of microbes and molecular identification of drug resistance using a platform known commercially as the Ibis T5000 universal biosensor. The PCR/electrospray ionization-mass spectrome