Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lawrence A. Schriefer"'
Autor:
Lisa J. Funkhouser-Jones, Rui Xu, Georgia Wilke, Yong Fu, Lawrence A. Schriefer, Heyde Makimaa, Rachel Rodgers, Elizabeth A. Kennedy, Kelli L. VanDussen, Thaddeus S. Stappenbeck, Megan T. Baldridge, L. David Sibley
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112680- (2023)
Summary: Cryptosporidiosis is a leading cause of life-threatening diarrhea in young children in resource-poor settings. To explore microbial influences on susceptibility, we screened 85 microbiota-associated metabolites for their effects on Cryptospo
Externí odkaz:
https://doaj.org/article/59e6a266f8ee48cab18b8af576086baf
Autor:
Dylan Lawrence, Danielle E. Campbell, Lawrence A. Schriefer, Rachel Rodgers, Forrest C. Walker, Marissa Turkin, Lindsay Droit, Miles Parkes, Scott A. Handley, Megan T. Baldridge
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
As our understanding of the importance of the human microbiota in health and disease grows, so does our need to carefully resolve and delineate its genomic content. 16S rRNA gene-based analyses yield important insights into taxonomic composition, and
Externí odkaz:
https://doaj.org/article/e1bda58c8870482f9ff965914e9590d2
Autor:
Somya Aggarwal, Forrest C Walker, James S Weagley, Broc T McCune, Xiaofen Wu, Lawrence A Schriefer, Heyde Makimaa, Dylan Lawrence, Pratyush Sridhar, Megan T Baldridge
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1011961 (2024)
Noroviruses (NoVs) are a leading cause of viral gastroenteritis. Despite global clinical relevance, our understanding of how host factors, such as antiviral cytokines interferons (IFNs), modulate NoV population dynamics is limited. Murine NoV (MNoV)
Externí odkaz:
https://doaj.org/article/156a71645a0f4958af0295641a001002
Autor:
Meagan E. Sullender, Linley R. Pierce, Mridula Annaswamy Srinivas, Stacey L. Crockett, Bria F. Dunlap, Rachel Rodgers, Lawrence A. Schriefer, Elizabeth A. Kennedy, Brittany M. Stewart, John G. Doench, Megan T. Baldridge, Robert C. Orchard
Publikováno v:
J Virol
Noroviruses are a leading cause of gastroenteritis worldwide, yet the molecular mechanisms of how host antiviral factors restrict norovirus infection are poorly understood. Here, we present a CRISPR activation screen that identifies mouse genes which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f03f77c585ba294e32b009f5ad006e3
https://doi.org/10.1128/jvi.00707-22
https://doi.org/10.1128/jvi.00707-22
Autor:
W. Alexander Stinson, Elizabeth A. Kennedy, Derek J. Platt, Wei Qian, Lawrence A. Schriefer, Jonathan J. Miner, Stefan T. Peterson, Dylan Lawrence, Rachel Rodgers, Amber M. Menos, Megan T. Baldridge, Cathrine A. Miner
Publikováno v:
Cell reports
SUMMARY STING modulates immunity by responding to bacterial and endogenous cyclic dinucleotides (CDNs). Humans and mice with STING gain-of-function mutations develop a syndrome known as STING-associated vasculopathy with onset in infancy (SAVI), whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30017299760c3324fb18e616fe2cf347
https://pubmed.ncbi.nlm.nih.gov/33979608
https://pubmed.ncbi.nlm.nih.gov/33979608
Autor:
Alexa N. Roth, Lawrence A. Schriefer, Cassandra E Thompson, Rachel Rodgers, Megan T. Baldridge, Jonathan J. Miner, Yuhao Li, Ebrahim Hassan, Stephanie M. Karst, Forrest C. Walker, Dylan Lawrence, Carla Blum-Johnston, Sanghyun Lee, Vincent R. Graziano, Broc T. McCune, Gowri Kalugotla, Larissa Lushniak, Stefan T. Peterson, Craig B. Wilen, Timothy J. Nice
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 3, p e1009402 (2021)
PLoS Pathogens, Vol 17, Iss 3, p e1009402 (2021)
Interferons (IFNs) are key controllers of viral replication, with intact IFN responses suppressing virus growth and spread. Using the murine norovirus (MNoV) system, we show that IFNs exert selective pressure to limit the pathogenic evolutionary pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8a8abf6cf93b20b07d2c4ab51b77be
https://pubmed.ncbi.nlm.nih.gov/33705489
https://pubmed.ncbi.nlm.nih.gov/33705489
Publikováno v:
Genome Research. 14:2457-2468
We report the identification of three new transcription regulatory elements that are associated with muscle gene expression in the nematodeCaenorhabditis elegans. Starting from a subset of well-characterized nematode muscle genes, we identified conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64acc2150b985e32241ff6ac9fd21a57
https://doi.org/10.1101/gr.2961104
https://doi.org/10.1101/gr.2961104
Publikováno v:
The Journal of Cell Biology
In C. elegans, assembly of hypodermal hemidesmosome-like structures called fibrous organelles is temporally and spatially coordinated with the assembly of the muscle contractile apparatus, suggesting that signals are exchanged between these cell type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ec506e7a85f52736db33a518402871
http://europepmc.org/articles/PMC2150558
http://europepmc.org/articles/PMC2150558
Autor:
Zheng Zuo, Lawrence A. Schriefer, Ankit Gupta, Ryan G. Christensen, Scot A. Wolfe, Gary D. Stormo
Publikováno v:
Nucleic Acids Research
We examine the use of high-throughput sequencing on binding sites recovered using a bacterial one-hybrid (B1H) system and find that improved models of transcription factor (TF) binding specificity can be obtained compared to standard methods of seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86077605d8dffa29783ab3273bddc250
https://pubmed.ncbi.nlm.nih.gov/21507886
https://pubmed.ncbi.nlm.nih.gov/21507886
Publikováno v:
Genetics. 184(1)
Mutations in the unc-82 locus of Caenorhabditis elegans were previously identified by screening for disrupted muscle cytoskeleton in otherwise apparently normal mutagenized animals. Here we demonstrate that the locus encodes a serine/threonine kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8705febe13e9918bd8b580746abb0222
https://pubmed.ncbi.nlm.nih.gov/19901071
https://pubmed.ncbi.nlm.nih.gov/19901071