Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Lawrence A. Menahan"'
Autor:
Lawrence A. Menahan, Richard L. Drake, Richard E. Peterson, Christopher K. Kelling, Marc J. van Rafelghemp
Publikováno v:
Journal of Biochemical Toxicology. 1:23-37
Perfluorodecanoic acid (PFDA) administration to adult male rats increased both the activity of hepatic malic enzyme and liver weight in a dose-dependent manner. Hepatomegaly and augmented activity of malic enzyme in liver were apparent within one day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7de3f4403b88c4a057bbf7d3663ed56
https://doi.org/10.1002/jbt.2570010304
https://doi.org/10.1002/jbt.2570010304
Publikováno v:
Toxicology and Applied Pharmacology. 91:497-501
Mechanical responses of isolated atria to (-)-isoproterenol and activities of myocardial pyruvate kinase and citrate synthase, enzymes involved in energy metabolism, were assessed in rats 7 days after 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c130871f13c0445aab0be19c0d50f42f
https://doi.org/10.1016/0041-008x(87)90072-x
https://doi.org/10.1016/0041-008x(87)90072-x
Publikováno v:
Toxicology Letters. 40:57-69
Energy metabolism and body composition were investigated in perfluorodecanoic acid (PFDA)-treated rats (single i.p. dose of 20, 40 or 80 mg/kg) and their respective pair-fed counterparts 7 days after dosing. Cumulative feed intake and body weight wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0a4304def024b66e53141963e87d08
https://doi.org/10.1016/0378-4274(88)90183-x
https://doi.org/10.1016/0378-4274(88)90183-x
Publikováno v:
Endocrinology. 107:671-676
Obese mice (C57BL/6J ob/ob) and their lean littermates were studied at various ages from immediately post weaning until 62 weeks of age, at which mortality increased markedly. Several age-related changes were noted. 1) Plasma glucose levels were elev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacc510a9099203b20d185c1b8f2ddaf
https://doi.org/10.1210/endo-107-3-671
https://doi.org/10.1210/endo-107-3-671
Publikováno v:
Life Sciences. 22:1033-1041
The active form (PDHa) and total activity of pyruvate dehydrogenase (PDH) were measured in homogenates from heart muscle, epididymal fat pads and liver of genetically obese hyperglycemic mice and compared with similar data derived from lean controls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3e89c466597c2b25482b206b7c0e11
https://doi.org/10.1016/0024-3205(78)90272-2
https://doi.org/10.1016/0024-3205(78)90272-2
Publikováno v:
Analytical Biochemistry. 113:379-385
A simple and sensitive assay for the quantitative determination of acetoacetyl-CoA (AcAc-CoA) in liver and heart is described. The method is based on incorporation of [ 14 C]acetyl-CoA into acid-stable nonvolatile material in the presence of avian HM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a1c08b05e24b28ed988b04d51fe4bd
https://doi.org/10.1016/0003-2697(81)90092-0
https://doi.org/10.1016/0003-2697(81)90092-0
Autor:
Lawrence A. Menahan
Publikováno v:
Mechanisms of Ageing and Development. 24:353-366
Changes of the pyruvate dehydrogenase complex in liver and epididymal fat pad were examined longitudinally in obese mice (C57BL/6J-ob/ob) and their lean controls as a function of age. Total pyruvate dehydrogenase in liver was expressed on several ref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10e7aaa7c600119681634fa72fe82c6
https://doi.org/10.1016/0047-6374(84)90120-9
https://doi.org/10.1016/0047-6374(84)90120-9
Publikováno v:
Fundamental and Applied Toxicology. 6:89-97
Efficiency of energy utilization was evaluated temporally in 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD, 50 μg/kg)-treated male Sprague-Dawley rats (275–300 g), their pair-fed counterparts, and a group with ad libitum access to ground feed. TCDD-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d773c931d1ad3dd7ca5d842ccc53c35a
https://doi.org/10.1016/0272-0590(86)90267-8
https://doi.org/10.1016/0272-0590(86)90267-8
Publikováno v:
Diabetologia. 14:47-51
Withdrawal of exogenous insulin and a subsequent fast (24 h) of alloxan diabetic rats stimulated rates of gluconeogenesis, urogenesis, ketogenesis, and amino acid release by in situ perfused livers when compared to those from normal, fasted rats. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8cf7b4085bdba654d81d39acd7d915
https://doi.org/10.1007/bf00429707
https://doi.org/10.1007/bf00429707
Autor:
Lawrence A. Menahan, Robert G. Kemp
Publikováno v:
Mechanisms of Ageing and Development. 20:195-203
Enzymatic activities of thymocytes isolated from Swiss albino mice were studied at various ages from immediately post weaning until 100 weeks of age, approaching the life expectancy of these animals. Between 5 and 10 weeks of age, the activities of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1aa811d7e0661c0c4abedebf358741
https://doi.org/10.1016/0047-6374(82)90087-2
https://doi.org/10.1016/0047-6374(82)90087-2