Efficacy and Safety of an Octreotide Implant in the Treatment of Patients With Acromegaly

Autor: Carla Chieffo, David M. Cook, Lawrence A. Frohman, Qinfang Xiang

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 98:4047-4054

Context: Acromegaly is caused by excessive GH secretion and IGF-I overproduction. The goals of treatment are to reduce GH and IGF-I values to normal and relieve the associated symptoms. Objective: The purpose of this article was to demonstrate that a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5314c91e196ee9047c6ca5ce99a89e2
https://doi.org/10.1210/jc.2013-2262

Treatment of pituitary-dependent Cushing's disease with the multireceptor ligand somatostatin analog pasireotide (SOM230): a multicenter, phase II trial

Autor: Jérôme Bertherat, Pamela U. Freda, Ashley B. Grossman, James W. Findling, Ke Hu, A. Tabarin, Yibin Wang, Beverly M. K. Biller, J. E. Glusman, Martin Reincke, William H. Ludlam, Peter J. Snyder, C. H. Darby, Lawrence A. Frohman, Shlomo Melmed, B. Atkinson, Marco Boscaro, Stephan Petersenn

Context: There is currently no medical therapy for Cushing’s disease that targets the pituitary adenoma. Availability of such a medical therapy would be a valuable therapeutic option for the management of this disorder. Objective: Our objective was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0faabd1d6dd1957bf689615dd03d571d
https://doi.org/10.1210/jc.2008-1008

Contributors

Autor: Lloyd Paul Aiello, Kyriaki S. Alatzoglou, Erik K. Alexander, Carolyn A. Allan, Bruno Allolio, Nobuyuki Amino, Bradley D. Anawalt, Peter Angelos, Valerie A. Arboleda, Richard J. Auchus, Lloyd Axelrod, Rebecca S. Bahn, H.W. Gordon Baker, MD, PhD, FRACP, Shlomi Barak, Randall B. Barnes, Andreas Barthel, Murat Bastepe, Emma K. Beardsley, Paolo Beck-Peccoz, Graeme I. Bell, Wenya Linda Bi, John P. Bilezikian, Manfred Blum, Steen J. Bonnema, Stefan R. Bornstein, Roger Bouillon, Andrew J.M. Boulton, Glenn D. Braunstein, F. Richard Bringhurst, Frank J. Broekmans, Marcello D. Bronstein, Edward M. Brown, Wendy A. Brown, Serdar E. Bulun, Henry B. Burch, Henry G. Burger, Richard O. Burney, Morton G. Burt, Enrico Cagliero, Glenda G. Callender, Maria Luiza Avancini Caramori, Robert M. Carey, Tobias Carling, Francesco Cavagnini, Jerry D. Cavallerano, Etienne Challet, Shu Jin Chan, R. Jeffrey Chang, Roland D. Chapurlat, V. Krishna Chatterjee, Francesco Chiofalo, Luca Chiovato, Kyung J. Cho, Emily Christison-Lagay, Daniel Christophe, George P. Chrousos, John A. Cidlowski, David R. Clemmons, Robert V. Considine, Marco Conti, Georges Copinschi, Kyle D. Copps, Michael A. Cowley, Leona Cuttler, Mehul T. Dattani, Stephen N. Davis, Mario De Felice, Leslie J. De Groot, David M. de Kretser, Ralph A. DeFronzo, Ahmed J. Delli, Marie B. Demay, Michael C. Dennedy, Roberto Di Lauro, Rosemary Dineen, Su Ann Ding, Sean F. Dinneen, Daniel J. Drucker, Jacques E. Dumont, Kathleen M. Dungan, Ian F. Dunn, Michael J. Econs, David A. Ehrmann, Graeme Eisenhofer, Berrin Ergun-Longmire, Erica A. Eugster, Sadaf I. Farooqi, Martin Fassnacht, Bart C.J.M. Fauser, Gianfranco Fenzi, Ele Ferrannini, David M. Findlay, Courtney Anne Finlayson, Delbert A. Fisher, Isaac R. Francis, Mason W. Freeman, Lawrence A. Frohman, Mark Frydenberg, Peter J. Fuller, Jason L. Gaglia, Gianluigi Galizia, Thomas J. Gardella, Katharine C. Garvey, Harry K. Genant, Michael S. German, Evelien F. Gevers, Francesca Pecori Giraldi, Linda C. Giudice, Andrea Giustina, Anna Glasier, Francis H. Glorieux, Allison B. Goldfine, Louis J. Gooren, David F. Gordon, Karen A. Gregerson, Raymon H. Grogan, Milton D. Gross, Ashley B. Grossman, Matthias Gruber, Valeria C. Guimarães, Mark Gurnell, Nadine G. Haddad, Daniel J. Haisenleder, David J. Handelsman, John B. Hanks, Mark J. Hannon, Erika Harno, Matthias Hebrok, Mark P. Hedger, Laszlo Hegedüs, Jerrold J. Heindel, Arturo Hernandez, Maria K. Herndon, Ken K.Y. Ho, Nelson D. Horseman, Ieuan A. Hughes, Christopher J. Hupfeld, Hero K. Hussain, Valeria Iodice, Benjamin C. James, J. Larry Jameson, Glenville Jones, Nathalie Josso, Harald Jüppner, Agata Juszczak, Jeffrey Kalish, Edwin L. Kaplan, Niki Karavitaki, Monika Karczewska-Kupczewska, Ahmed Khattab, David C. Klein, Ronald Klein, Gunnar Kleinau, Michaela Koontz, John J. Kopchick, Peter Kopp, Irina Kowalska, Stephen M. Krane, Knut Krohn, Henry M. Kronenberg, Elizabeth M. Lamos, Andrea Lania, Sue Lynn Lau, Edward R. Laws, John H. Lazarus, Diana L. Learoyd, Harold E. Lebovitz, Åke Lenmark, Edward O. List, Kate Loveland, David A. Low, Paolo E. Macchia, Noel K. Maclaren, Geraldo Madeiros-Neto, Carine Maenhaut, Christa Maes, Katharina M. Main, Carl D. Malchoff, Diana M. Malchoff, Rayaz A. Malik, Susan J. Mandel, Christos S. Mantzoros, Eleftheria Maratos-Flier, Michele Marino, John C. Marshall, T. John Martin, Thomas F.J. Martin, Christopher J. Mathias, Elizabeth A. McGee, Travis McKenzie, Robert I. McLachlan, Juris J. Meier, Shlomo Melmed, Boyd E. Metzger, Heino F.L. Meyer-Bahlburg, Robert P. Millar, Walter L. Miller, Madhusmita Misra, Mark E. Molitch, Molly B. Moravek, Damian G. Morris, Sapna Nagar, Jon Nakamoto, Maria I. New, Lynnette K. Nieman, John H. Nilson, Georgia Ntali, Moira O’Bryan, Stephen O’Rahilly, Kjell Öberg, Jerrold M. Olefsky, Matthew T. Olson, Karel Pacak, Furio Pacini, Shetal H. Padia, Ralf Paschke, Francisco J. Pasquel, Katherine Wesseling Perry, Luca Persani, Louis H. Philipson, Christian Pina, Frank B. Pomposelli, John T. Potts, Charmian A. Quigley, Marcus O. Quinkler, Christine Campion Quirk, Ewa Rajpert-De Meyts, Eric Ravussin, David W. Ray, Samuel Refetoff, Ravi Retnakaran, Rodolfo A. Rey, Christopher J. Rhodes, E. Chester Ridgway, Gail P. Risbridger, Robert A. Rizza, Bruce G. Robinson, Pierre P. Roger, Michael G. Rosenfeld, Robert L. Rosenfield, Peter Rossing, Robert T. Rubin, Ileana G.S. Rubio, Neil B. Ruderman, Jose Russo, Irma H. Russo, Isidro B. Salusky, Nanette Santoro, Kathleen M. Scully, Patrick M. Sexton, Gerald I. Shulman, Paolo S. Silva, Shonni J. Silverberg, Frederick R. Singer, Niels E. Skakkebaek, Malgorzata E. Skaznik-Wikiel, Dorota Skowronska-Krawczyk, Carolyn L. Smith, Philip W. Smith, Roger Smith, Steven R. Smith, Peter J. Snyder, Donald L. St. Germain, René St-Arnaud, Donald F. Steiner, Paul M. Stewart, Marek Strączkowski, Jerome F. Strauss, Dennis M. Styne, Karena L. Swan, Ronald S. Swerdloff, Lyndal J. Tacon, Javier A. Tello, Rajesh V. Thakker, Christopher J. Thompson, Henri J.L.M. Timmers, Jorma Toppari, Michael L. Traub, Michael A. Tsoukas, Robert Udelsman, Guillermo E. Umpierrez, Greet Van den Berghe, Gilbert Vassart, Ashley H. Vernon, Eric Vilain, Theo J. Visser, Paolo Vitti, Geoffrey A. Walford, Christina Wang, Anthony P. Weetman, Nancy L. Weigel, Gordon C. Weir, Roy E. Weiss, Anne White, Kenneth E. White, Morris F. White, Michael P. Whyte, Wilmar M. Wiersinga, Holger S. Willenberg, Joseph I. Wolfsdorf, Fredric E. Wondisford, Ka Kit Wong, John J. Wysolmerski, Mabel Yau, Morag J. Young, Lisa M. Younk, Run Yu, Tony Yuen, Martha A. Zeiger, Bernard Zinman, R. Thomas Zoeller

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::052e98fd342096e0bba7cb16e76034dd
https://doi.org/10.1016/b978-0-323-18907-1.01002-7

Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects

Autor: Lawrence A. Frohman, John J. Kopchick, Juan Ding, Lucila Sackmann-Sala

Publikováno v: Growth Hormone & IGF Research. 19:471-477

Objective To identify biomarkers of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) action in human serum. Background The search for new markers of GH activity has received extensive attention given that the current biomarkers (IGF-1, IG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebafc3672743a77bda145c77de0ee9a2
https://doi.org/10.1016/j.ghir.2009.03.001

Synthesis and biological evaluation of mouse growth hormone-releasing factor

Autor: Mushtaq Ahmad, Thomas R. Downs, Edgar P. Heimer, Theodore Lambros, Lawrence A. Frohman, Arthur Felix

Publikováno v: International Journal of Peptide and Protein Research. 37:552-555

The recently described mouse growth hormone-releasing factor (mGRF) was synthesized by the solid phase procedure, purified by 2 stages of preparative high performance liquid chromatography and fully characterized. The biologic activity of the 42-amin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a960d6a2994c24fed181340c8b0ab87
https://doi.org/10.1111/j.1399-3011.1991.tb00774.x