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Autor:
Laty G. Thiam, Kirsty McHugh, Aboubacar Ba, Rebecca Li, Yicheng Guo, Mariama N. Pouye, Awa Cisse, Dimitra Pipini, Fatoumata Diallo, Seynabou D. Sene, Saurabh D. Patel, Alassane Thiam, Bacary D. Sadio, Alassane Mbengue, Inés Vigan-Womas, Zizhang Sheng, Lawrence Shapiro, Simon J. Draper, Amy K. Bei
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Vaccines to the Plasmodium falciparum reticulocyte binding-like protein homologue 5 (PfRH5) target the blood-stage of the parasite life cycle. PfRH5 has the potential to trigger the production of strain-transcendent antibodies and has proven
Externí odkaz:
https://doaj.org/article/e107ccb140a3481e807421a3633b07ca
Publikováno v:
Society. 59:195-197
Autor:
Richard Quintana-Feliciano, Jithesh Kottur, Mi Ni, Rikhia Ghosh, Leslie Salas-Estrada, Goran Ahlsen, Olga Rechkoblit, Lawrence Shapiro, Marta Filizola, Gang Fang, Aneel K. Aggarwal
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Burkholderia cenocepacia is an opportunistic and infective bacterium containing an orphan DNA methyltransferase called M.BceJIV with roles in regulating gene expression and motility of the bacterium. M.BceJIV recognizes a GTWWAC motif (where
Externí odkaz:
https://doaj.org/article/2beb0819c5a6441cae69edcef87014d6
Autor:
Qian Wang, Ian A. Mellis, Jerren Ho, Anthony Bowen, Theresa Kowalski-Dobson, Riccardo Valdez, Phinikoula S. Katsamba, Madeline Wu, Caitlin Lee, Lawrence Shapiro, Aubree Gordon, Yicheng Guo, David D. Ho, Lihong Liu
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
The recently dominant SARS-CoV-2 Omicron JN.1 has evolved into multiple sublineages, with recurrent spike mutations R346T, F456L, and T572I, some of which exhibit growth advantages, such as KP.2 and KP.3. We investigated these mutations in JN.1, exam
Externí odkaz:
https://doaj.org/article/bc84833b02134f64ae87a0a39aa1751b
Autor:
Manxue Jia, Hanjun Zhao, Nicholas C. Morano, Hong Lu, Yin-Ming Lui, Haijuan Du, Jordan E. Becker, Kwok-Yung Yuen, David D. Ho, Peter D. Kwong, Lawrence Shapiro, Kelvin Kai-Wang To, Xueling Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Avian influenza A virus H7N9 causes severe human infections with >30% fatality. Currently, there is no H7N9-specific prevention or treatment for humans. Here, from a 2013 H7N9 convalescent case in Hong Kong, we isolate four hemagglutinin (HA
Externí odkaz:
https://doaj.org/article/83d250f54cd64895b1f4e8c2f5942319
Autor:
Jianliang Xu, Tongqing Zhou, Krisha McKee, Baoshan Zhang, Cuiping Liu, Alexandra F. Nazzari, Amarendra Pegu, Chen‐Hsiang Shen, Jordan E. Becker, Michael F. Bender, Payton Chan, Anita Changela, Ridhi Chaudhary, Xuejun Chen, Tal Einav, Young Do Kwon, Bob C. Lin, Mark K. Louder, Jonah S. Merriam, Nicholas C. Morano, Sijy O'Dell, Adam S. Olia, Reda Rawi, Ryan S. Roark, Tyler Stephens, I‐Ting Teng, Emily Tourtellott‐Fogt, Shuishu Wang, Eun Sung Yang, Lawrence Shapiro, Yaroslav Tsybovsky, Nicole A. Doria‐Rose, Rafael Casellas, Peter D. Kwong
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Broadly neutralizing antibodies are proposed as therapeutic and prophylactic agents against HIV‐1, but their potency and breadth are less than optimal. This study describes the immunization of a llama with the prefusion‐stabilized HIV‐
Externí odkaz:
https://doaj.org/article/2af27b428ce0453586e0f60b99fd2446
Autor:
Weber, Arne M.
Publikováno v:
Zeitschrift für philosophische Forschung, 2011 Jan 01. 65(4), 610-614.
Externí odkaz:
http://dx.doi.org/10.3196/004433011798806916
Autor:
Glenn B. Siniscalchi
Publikováno v:
The Catholic Biblical Quarterly. 81:554-556
Autor:
Adam S. Olia, Madhu Prabhakaran, Darcy R. Harris, Crystal Sao-Fong Cheung, Rebecca A. Gillespie, Jason Gorman, Abigayle Hoover, Nicholas C. Morano, Amine Ourahmane, Abhinaya Srikanth, Shuishu Wang, Weiwei Wu, Tongqing Zhou, Sarah F. Andrews, Masaru Kanekiyo, Lawrence Shapiro, Adrian B. McDermott, Peter D. Kwong
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The VH6-1 class of antibodies includes some of the broadest and most potent antibodies that neutralize influenza A virus. Here, we elicit and isolate anti-idiotype antibodies against germline versions of VH6-1 antibodies, use these to sort human leuk
Externí odkaz:
https://doaj.org/article/086e3f3dbf7c436b9fc0aa65fce2326a