Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Lawrence, Korngut"'
Autor:
Hans-Peter Müller, Agessandro Abrahao, Christian Beaulieu, Michael Benatar, Annie Dionne, Angela Genge, Richard Frayne, Simon J. Graham, Summer Gibson, Lawrence Korngut, Collin Luk, Robert C. Welsh, Lorne Zinman, Jan Kassubek, Sanjay Kalra
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103633- (2024)
Objective: The corticospinal tract (CST) reveals progressive microstructural alterations in ALS measurable by DTI. The aim of this study was to evaluate fractional anisotropy (FA) along the CST as a longitudinal marker of disease progression in ALS.
Externí odkaz:
https://doaj.org/article/0e55aa75241840ef90189c0899f2aef4
Autor:
Vanessa Rangel Miller, Heather Richbourg, Jerry Vockley, Omid Japalaghi, Moeenaldeen AlSayed, Mark Kiel, Stephanie Monteleone, Peter Baker, II, Sean Daugherty, Aneal Khan, Lawrence Korngut, Deborah Marsden, Ana Morales, Nicole Miller
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 100909- (2024)
Externí odkaz:
https://doaj.org/article/c9ad9e85b1844cc888a0a8552e78d684
Autor:
Marziye Eshghi, Yana Yunusova, Kathryn P. Connaghan, Bridget J. Perry, Marc F. Maffei, James D. Berry, Lorne Zinman, Sanjay Kalra, Lawrence Korngut, Angela Genge, Annie Dionne, Jordan R. Green
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Although speech declines rapidly in some individuals with amyotrophic lateral sclerosis (ALS), longitudinal changes in speech have rarely been characterized. The study objectives were to model the rate of decline in speaking rate and speech
Externí odkaz:
https://doaj.org/article/d1d83f13de6d4055a49c73802aecdbd7
Autor:
Michael Pugliese, Kylie Tingley, Andrea Chow, Nicole Pallone, Maureen Smith, Alvi Rahman, Pranesh Chakraborty, Michael T. Geraghty, Julie Irwin, Laure Tessier, Stuart G. Nicholls, Martin Offringa, Nancy J. Butcher, Ryan Iverson, Tammy J. Clifford, Sylvia Stockler, Brian Hutton, Karen Paik, Jessica Tao, Becky Skidmore, Doug Coyle, Kathleen Duddy, Sarah Dyack, Cheryl R. Greenberg, Shailly Jain Ghai, Natalya Karp, Lawrence Korngut, Jonathan Kronick, Alex MacKenzie, Jennifer MacKenzie, Bruno Maranda, John J. Mitchell, Murray Potter, Chitra Prasad, Andreas Schulze, Rebecca Sparkes, Monica Taljaard, Yannis Trakadis, Jagdeep Walia, Beth K. Potter, Canadian Inherited Metabolic Diseases Research Network
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-15 (2020)
Abstract Background Inherited metabolic diseases (IMDs) are a group of individually rare single-gene diseases. For many IMDs, there is a paucity of high-quality evidence that evaluates the effectiveness of clinical interventions. Clinical effectivene
Externí odkaz:
https://doaj.org/article/ca64ab0b801a44c5b984cecb91d4a8b8
Autor:
Komal Bharti, Simon J. Graham, Michael Benatar, Hannah Briemberg, Sneha Chenji, Nicolas Dupré, Annie Dionne, Richard Frayne, Angela Genge, Lawrence Korngut, Collin Luk, Lorne Zinman, Sanjay Kalra, for the Canadian ALS Neuroimaging Consortium (CALSNIC)
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Amyotrophic lateral sclerosis (ALS) is a multisystem neurodegenerative disorder characterized by progressive degeneration of upper motor neurons and lower motor neurons, and frontotemporal regions resulting in impaired bulbar, limb, and cognitive fun
Externí odkaz:
https://doaj.org/article/70ccadd2366f47ac9f86a27e1714a364
Autor:
Komal Bharti, Muhammad Khan, Christian Beaulieu, Simon J. Graham, Hannah Briemberg, Richard Frayne, Angela Genge, Lawrence Korngut, Lorne Zinman, Sanjay Kalra
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102385- (2020)
Amyotrophic lateral sclerosis (ALS) is characterized primarily by motor neuron but also frontotemporal lobar degeneration. Although the cerebellum is involved in both motor and cognitive functions, little is known of its role in ALS. We targeted the
Externí odkaz:
https://doaj.org/article/bff5b75c03904357af75770f43d5fbe6
Autor:
Libby Wood, Guillaume Bassez, Corinne Bleyenheuft, Craig Campbell, Louise Cossette, Aura Cecilia Jimenez-Moreno, Yi Dai, Hugh Dawkins, Jorge Alberto Diaz Manera, Celine Dogan, Rasha el Sherif, Barbara Fossati, Caroline Graham, James Hilbert, Kristinia Kastreva, En Kimura, Lawrence Korngut, Anna Kostera-Pruszczyk, Christopher Lindberg, Bjorn Lindvall, Elizabeth Luebbe, Anna Lusakowska, Radim Mazanec, Giovani Meola, Liannna Orlando, Masanori P. Takahashi, Stojan Peric, Jack Puymirat, Vidosava Rakocevic-Stojanovic, Miriam Rodrigues, Richard Roxburgh, Benedikt Schoser, Sonia Segovia, Andriy Shatillo, Simone Thiele, Ivailo Tournev, Baziel van Engelen, Stanislav Vohanka, Hanns Lochmüller
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-11 (2018)
Abstract Background Myotonic Dystrophy is the most common form of muscular dystrophy in adults, affecting an estimated 10 per 100,000 people. It is a multisystemic disorder affecting multiple generations with increasing severity. There are currently
Externí odkaz:
https://doaj.org/article/cc2d675314b54dc3be1bfaec5e0a7e85
Autor:
Beth K. Potter, Brian Hutton, Tammy J. Clifford, Nicole Pallone, Maureen Smith, Sylvia Stockler, Pranesh Chakraborty, Pauline Barbeau, Chantelle M. Garritty, Michael Pugliese, Alvi Rahman, Becky Skidmore, Laure Tessier, Kylie Tingley, Doug Coyle, Cheryl R. Greenberg, Lawrence Korngut, Alex MacKenzie, John J. Mitchell, Stuart Nicholls, Martin Offringa, Andreas Schulze, Monica Taljaard, In collaboration with the Canadian Inherited Metabolic Diseases Research Network
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background Inherited metabolic diseases (IMD) are a large group of rare single-gene disorders that are typically diagnosed early in life. There are important evidence gaps related to the comparative effectiveness of therapies for IMD, which
Externí odkaz:
https://doaj.org/article/935184723f7a4133894c758541043d09
Publikováno v:
Tuesday, April 25.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d92fa96de14ba82ee3dc1e63e0dd1a7
https://doi.org/10.1212/wnl.0000000000203257
https://doi.org/10.1212/wnl.0000000000203257
Autor:
Corey T, McMillan, Joanne, Wuu, Katya, Rascovsky, Stephanie, Cosentino, Murray, Grossman, Lauren, Elman, Colin, Quinn, Luis, Rosario, Jessica H, Stark, Volkan, Granit, Hannah, Briemberg, Sneha, Chenji, Annie, Dionne, Angela, Genge, Wendy, Johnston, Lawrence, Korngut, Christen, Shoesmith, Lorne, Zinman, Sanjay, Kalra, Michael, Benatar
Publikováno v:
Amyotroph Lateral Scler Frontotemporal Degener
OBJECTIVE: Amyotrophic lateral sclerosis (ALS) is a multi-system disorder characterized primarily by motor neuron degeneration, but may be accompanied by cognitive dysfunction. Statistically appropriate criteria for establishing cognitive impairment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc2e3624c281be53e3f4a2845c4c27a
https://doi.org/10.1080/21678421.2022.2039713
https://doi.org/10.1080/21678421.2022.2039713