Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Lawrence, Helson"'
Autor:
Muhammed Majeed, Lawrence Helson
Publikováno v:
Anticancer Research. 39:3423-3427
Current clinical failure to cure primary glioblastoma multiforme in virtually all adult patients is due to genetic aberrations, molecular heterogeneity, and clonal evolution of tumor stem and differentiated cells within the core tumor, leading to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d203af05f57028ac3bc9de34a58f81
https://doi.org/10.21873/anticanres.13487
https://doi.org/10.21873/anticanres.13487
Radiation-induced Demyelination and Remyelination in the Central Nervous System: A Literature Review
Autor:
Lawrence Helson
Publikováno v:
Anticancer Research. 38:4999-5002
Therapeutic radiation applied to the central nervous system concomitant with or followed by surgery and chemotherapy induces significant pathologic demyelination depending upon tumor volume, dosage, field of treatment, and age of patient, with conseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466a158c0485e63f4aa58ac48c796c98
https://doi.org/10.21873/anticanres.12818
https://doi.org/10.21873/anticanres.12818
Publikováno v:
Anticancer Research. 37:2159-2171
The failure of chemotherapy and radiation therapy to achieve long-term remission or cure in patients with glioblastoma (GBM) is, in a large part, due to the suppression of the immune system induced by the tumors themselves. These tumors adapt to trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea3df27d68e46b6d32adadec7a3d4ec
https://doi.org/10.21873/anticanres.11551
https://doi.org/10.21873/anticanres.11551
Autor:
Lawrence Helson, Muhammed Majeed
Publikováno v:
Biomedical Journal of Scientific & Technical Research. 22
Glioblastoma multiforme is characterized by tumor cell heterogeneity, and by recurrent invasive tumors following conventional radiation, cytotoxic drugs, and limited ablative surgery [1-5]...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a49b9fd7733ed112f80a547e726f719
https://doi.org/10.26717/bjstr.2019.22.003748
https://doi.org/10.26717/bjstr.2019.22.003748
Autor:
Annie Bouchard, Amalendu Prakash Ranjan, Muhammed Majeed, Jamboor K. Vishwanatha, Andrew Gdowski, Anindita Mukerjee, Lawrence Helson
Publikováno v:
Journal of Biomedical Nanotechnology. 12:679-688
Non-small-cell lung cancer therapy is a challenge due to poor prognosis and low survival rate. There is an acute need for advanced therapies having higher drug efficacy, low immunogenicity and fewer side effects which will markedly improve patient co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c86bec573e03e8c393b034ab063dc46
https://doi.org/10.1166/jbn.2016.2207
https://doi.org/10.1166/jbn.2016.2207
Autor:
Albert Licollari, Lawrence Helson, Richard Greil, Aimin Tan, Muhammad Majeed, Brigitta Vcelar, Gordon T. Bolger
Publikováno v:
Anticancer research. 37(7)
Background/aim The aim of this study was to investigate the distribution of curcumin (in the form of Lipocurc™) and its major metabolite tetrahydrocurcumin (THC) in Beagle dog and human red blood cells, peripheral blood mononuclear cells (PBMC) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73253c68f99971bd9b61a49903b4b64
https://pubmed.ncbi.nlm.nih.gov/28668837
https://pubmed.ncbi.nlm.nih.gov/28668837
Autor:
Lawrence Helson
Publikováno v:
BioFactors. 39:21-26
Curcumin interacts with a large number of extra- and intracellular targets in a biphasic dose-dependent manner. It controls inflammation, oxidative stress, cell survival, cell secretion, homeostasis, and proliferation. Its mechanisms of action are ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4234409727b8f1770ca428e9554ba319
https://doi.org/10.1002/biof.1080
https://doi.org/10.1002/biof.1080
Publikováno v:
Brain injury. 30(9)
Background: Pro-inflammatory cytokines play an essential role in maintenance of normal brain function as well as in repair after traumatic brain injuries (TBI). However, massive and uncontrolled release of these cytokines, particularly interleukin (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7382d1338d46fcc44d0b9b2a5b6a0290
https://pubmed.ncbi.nlm.nih.gov/27261102
https://pubmed.ncbi.nlm.nih.gov/27261102
Autor:
Albert Licollari, Lawrence Helson, George M. Shopp, Aimin Tan, John C. Fanaras, Yanxin Wu, Molly Wong, Gordon T. Bolger
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1028
Tetrahydrocurcumin (THC), a major metabolite of curcumin, is often quantified by LC-MS or LC-MS/MS using acidic mobile phases due to the concern of its instability in a basic medium. However, acidic mobile phases often lead to poor chromatography (e.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d9b84f56147e17ca3de6b4f25b03a1
https://pubmed.ncbi.nlm.nih.gov/27327398
https://pubmed.ncbi.nlm.nih.gov/27327398
Autor:
Burkhard, Kloesch, Lukas, Gober, Silvia, Loebsch, Brigitta, Vcelar, Lawrence, Helson, Guenter, Steiner
Publikováno v:
In vivo (Athens, Greece). 30(4)
The polyphenol curcumin is produced in the rhizome of Curcuma longa and exhibits potent anti-inflammatory, antioxidant, and chemopreventive activities. Due to the fact that curcumin is poorly soluble in water, many delivery systems have been develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08f4c3105e7a73086461c2b28fe658e0
https://pubmed.ncbi.nlm.nih.gov/27381602
https://pubmed.ncbi.nlm.nih.gov/27381602