Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lawrence, Chinn"'
Publikováno v:
PEC Innovation, Vol 2, Iss , Pp 100153- (2023)
Objective: Patient comprehension of informed consent and demonstration of procedural understanding is often lacking in anesthesiology. The purpose of this study was to determine if patient communication in anesthesiology is being conducted effectivel
Externí odkaz:
https://doaj.org/article/fe4f579ea928488ab5ebd28f01b87b56
Autor:
Edward Htun van der Horst, Lawrence Chinn, Min Wang, Timothy Velilla, Hoang Tran, Yarrow Madrona, Andrew Lam, May Ji, Timothy C. Hoey, Aaron K. Sato
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 4, Pp 355-364 (2009)
The receptor tyrosine kinase MET is a major component controlling the invasive growth program in embryonic development and in invasive malignancies. The discovery of therapeutic antibodies against MET has been difficult, and antibodies that compete w
Externí odkaz:
https://doaj.org/article/6b20f7361f4546d4aaef41486f071992
Autor:
Edward Htun van der Horst, Brendon T. Frank, Lawrence Chinn, Angela Coxon, Shyun Li, Fanny Polesso, Anthony Slavin, Astrid Ruefli-Brasse, Holger Wesche
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 4, Pp 340-346 (2008)
Midkine (MDK) is a heparin-binding growth factor involved in growth, survival, migration, and differentiation of various target cells and dysregulation of MDK signaling is implicated in a variety of inflammatory diseases and cancers. Although MDK has
Externí odkaz:
https://doaj.org/article/536b22dbcd454592b9a9dd88e9acc18f
Autor:
Randall L. Halcomb, Amanda Valdiosera, David Y. Jackson, Lawrence Chinn, Jonathan S. Melnick, Migone Thi Sau, Mark R. Flory, Derrick Houser, Edward H. van der Horst, Maureen Fitch-Bruhns, Simeon Bowers, Edward Ha, Jorge Monteon, Jan Willem Theunissen, Gary Probst, Tiffany Wong, Paul W. Sauer, Zoia Levashova, Kristy Venstrom, Abel Bermudez, Sindy Liao-Chan, Christopher R. Behrens
Publikováno v:
Mol Pharm
Conventional antibody–drug conjugates (ADCs) are heterogeneous mixtures of chemically distinct molecules that vary in both drugs/antibody (DAR) and conjugation sites. Suboptimal properties of heterogeneous ADCs have led to new site-specific conjuga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d883318e923b6b79e4a53f04cf24bb2c
https://doi.org/10.1021/acs.molpharmaceut.5b00432
https://doi.org/10.1021/acs.molpharmaceut.5b00432
Publikováno v:
Open Journal of Anesthesiology. :1-7
Background: As much as 80% of US adults search online for health related information. The value of the information is limited by the patients’ ability to comprehend it. Despite the recommendation by the American Medical Association (AMA) to provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8af528f74c38454193f58edd42793127
https://doi.org/10.4236/ojanes.2014.41001
https://doi.org/10.4236/ojanes.2014.41001
Autor:
Min Wang, Timothy Velilla, Timothy Hoey, Yarrow Madrona, Andrew Lam, Aaron K. Sato, May Ji, Edward Thein Htun van der Horst, Lawrence Chinn, Hoang Tran
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 4, Pp 355-364 (2009)
The receptor tyrosine kinase MET is a major component controlling the invasive growth program in embryonic development and in invasive malignancies. The discovery of therapeutic antibodies against MET has been difficult, and antibodies that compete w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1bf38d06b212c2014b68352a6024c6
http://www.sciencedirect.com/science/article/pii/S147655860980064X
http://www.sciencedirect.com/science/article/pii/S147655860980064X
Autor:
Gregory M, Hayes, Belinda, Cairns, Zoia, Levashova, Lawrence, Chinn, Myra, Perez, Jan-Willem, Theunissen, Sindy, Liao-Chan, Abel, Bermudez, Mark R, Flory, Karl J, Schweighofer, Edward, H van der Horst
Publikováno v:
American journal of translational research. 7(6)
Soft tissue sarcoma (STS) is a heterogenous tumor arising from the embryonic mesoderm represented by approximately 50 histological subtypes. Effective therapeutic intervention is lacking for recurrent, late stage and metastatic disease. CD39, a cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fb25e0153d13a8f2d5c3b6112897862
https://pubmed.ncbi.nlm.nih.gov/26279761
https://pubmed.ncbi.nlm.nih.gov/26279761
Autor:
Astrid Strelow, Timothy Hoey, Holger Wesche, Scott Powers, Jessica Orf, Anthony J. Slavin, Shyun Li, Minqing Rong, Ken Q. C. Nguyen, Lawrence Chinn, Yan Degenhardt, Edward H. van der Horst, Lei-Hoon See
Publikováno v:
Proceedings of the National Academy of Sciences. 102:15901-15906
Metastasis of primary tumors leads to a very poor prognosis for patients suffering from cancer. Although it is well established that not every tumor will eventually metastasize, it is less clear whether primary tumors acquire genetic alterations in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e1f8a12c6493944521e0017dd61dd7
https://doi.org/10.1073/pnas.0508014102
https://doi.org/10.1073/pnas.0508014102
Autor:
Mark H. Ginsberg, Edward H. van der Horst, Hoang Tran, Dana Duey, Belinda Cairns, Lawrence Chinn, Joseph Zachwieja, Timothy Velilla, Joseph M. Cantor, John Lippincott, Gregory M. Hayes, Zoia Levashova
Publikováno v:
International Journal of Cancer
CD98 is expressed on several tissue types and specifically upregulated on fast‐cycling cells undergoing clonal expansion. Various solid (e.g., nonsmall cell lung carcinoma) as well as hematological malignancies (e.g., acute myeloid leukemia) overex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16df9b6475e72321d5a7500d0e694fed
https://pubmed.ncbi.nlm.nih.gov/25556716
https://pubmed.ncbi.nlm.nih.gov/25556716
Publikováno v:
Cancer Research. 76:LB-250
Lung cancer is the leading cause of cancer-related deaths in the world. 85% of these cancers are non-small cell lung cancers (NSCLC) and the majority of these patients being diagnosed with advanced disease. Although standard of care initially shows c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ebd4ace84ea278b02c1022986fcc2f2
https://doi.org/10.1158/1538-7445.am2016-lb-250
https://doi.org/10.1158/1538-7445.am2016-lb-250